Publications by authors named "Marc S Robillard"

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Click-to-Release for Controlled Immune Cell Activation: Tumor-Targeted Unmasking of an IL12 Prodrug.
Martijn H den Brok, Kim E de Roode, Luc H M Zijlmans, Laurens H J Kleijn, Marleen H M E van Stevendaal, Marc S Robillard

Pharmaceuticals (Basel)· September 2025

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Toward Realization of Bioorthogonal Chemistry in the Clinic.
Kim E de Roode, Raffaella Rossin, Marc S Robillard

Top Curr Chem (Cham)· March 2025

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Ortho-functionalized pyridinyl-tetrazines break the inverse correlation between click reactivity and cleavage yields in click-to-release chemistry.
Ron M Versteegen, Raffaella Rossin, Ivo A W Filot, Freek J M Hoeben, Arthur H A M van Onzen, Marc S Robillard

Commun Chem· December 2024

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Author Correction: Ortho-functionalized pyridinyl-tetrazines break the inverse correlation between click reactivity and cleavage yields in click-to-release chemistry.
Ron M Versteegen, Raffaella Rossin, Ivo A W Filot, Freek J M Hoeben, Arthur H A M van Onzen, Marc S Robillard

Commun Chem· December 2024

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A Concise Synthetic Approach to Highly Reactive Click-to-Release Trans-Cyclooctene Linkers.
Bing Liu, Wolter Ten Hoeve, Ron M Versteegen, Raffaella Rossin, Laurens H J Kleijn, Marc S Robillard

Chemistry· August 2023

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Click-to-Release: Cleavable Radioimmunoimaging with [Zr]Zr-DFO--Cyclooctene-Trastuzumab Increases Tumor-to-Blood Ratio.
Maria Vlastara, Raffaella Rossin, Freek J M Hoeben, Kim E de Roode, Milou Boswinkel, Marc S Robillard

Theranostics· August 2023

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Bioorthogonal chemistry.
Samuel L Scinto, Didier A Bilodeau, Robert Hincapie, Wankyu Lee, Sean S Nguyen, Marc S Robillard

Nat Rev Methods Primers· April 2021

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Fluorogenic Bifunctional trans-Cyclooctenes as Efficient Tools for Investigating Click-to-Release Kinetics.
Mark A R de Geus, Elmer Maurits, Alexi J C Sarris, Thomas Hansen, Max S Kloet, Marc S Robillard

Chemistry· August 2020

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Bioorthogonal Tetrazine Carbamate Cleavage by Highly Reactive -Cyclooctene.
Arthur H A M van Onzen, Ron M Versteegen, Freek J M Hoeben, Ivo A W Filot, Raffaella Rossin, Marc S Robillard

J Am Chem Soc· June 2020

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-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging.
E Johanna L Stéen, Jesper T Jørgensen, Kerstin Johann, Kamilla Nørregaard, Barbara Sohr, Marc S Robillard

ACS Nano· January 2020

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Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging.
Patricia E Edem, Jean-Philippe Sinnes, Stefanie Pektor, Nicole Bausbacher, Raffaella Rossin, Marc S Robillard

EJNMMI Res· May 2019

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Tetrazine- trans-Cyclooctene Chemistry Applied to Fabricate Self-Assembled Fluorescent and Radioactive Nanoparticles for in Vivo Dual Mode Imaging.
Arthur H A M van Onzen, Raffaella Rossin, Albertus P H J Schenning, Klaas Nicolay, Lech-Gustav Milroy, Marc S Robillard

Bioconjug Chem· March 2019

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Author Correction: Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice.
Raffaella Rossin, Ron M Versteegen, Jeremy Wu, Alisher Khasanov, Hans J Wessels, Marc S Robillard

Nat Commun· January 2019

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Click-to-Release from trans-Cyclooctenes: Mechanistic Insights and Expansion of Scope from Established Carbamate to Remarkable Ether Cleavage.
Ron M Versteegen, Wolter Ten Hoeve, Raffaella Rossin, Mark A R de Geus, Henk M Janssen, Marc S Robillard

Angew Chem Int Ed Engl· August 2018

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Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans-Cyclooctene-Modified Epitopes.
Anouk M F van der Gracht, Mark A R de Geus, Marcel G M Camps, Tracy J Ruckwardt, Alexi J C Sarris, Marc S Robillard

ACS Chem Biol· June 2018

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Fluorescence- and multispectral optoacoustic imaging for an optimized detection of deeply located tumors in an orthotopic mouse model of pancreatic carcinoma.
Joanna Napp, Marieke A Stammes, Jing Claussen, Hendrica A J M Prevoo, Cornelis F M Sier, Marc S Robillard

Int J Cancer· May 2018

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Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice.
Raffaella Rossin, Ron M Versteegen, Jeremy Wu, Alisher Khasanov, Hans J Wessels, Marc S Robillard

Nat Commun· May 2018

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DOTA-tetrazine probes with modified linkers for tumor pretargeting.
Tilman Läppchen, Raffaella Rossin, Tiemen R van Mourik, Guillaume Gruntz, Freek J M Hoeben, Marc S Robillard

Nucl Med Biol· December 2017

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Metal-Free Cycloaddition Chemistry Driven Pretargeted Radioimmunotherapy Using α-Particle Radiation.
Manankumar A Shah, Xiuli Zhang, Raffaella Rossin, Marc S Robillard, Darrell R Fisher

Bioconjug Chem· December 2017

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Triggered Drug Release from an Antibody-Drug Conjugate Using Fast "Click-to-Release" Chemistry in Mice.
Raffaella Rossin, Sander M J van Duijnhoven, Wolter Ten Hoeve, Henk M Janssen, Laurens H J Kleijn, Marc S Robillard

Bioconjug Chem· July 2016

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Bioresponsive probes for molecular imaging: concepts and in vivo applications.
Sander M J van Duijnhoven, Marc S Robillard, Sander Langereis, Holger Grüll

Contrast Media Mol Imaging· May 2016

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Diabody Pretargeting with Click Chemistry In Vivo.
Sander M J van Duijnhoven, Raffaella Rossin, Sandra M van den Bosch, Michael P Wheatcroft, Peter J Hudson, Marc S Robillard

J Nucl Med· September 2015

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Development of Radiolabeled Membrane Type-1 Matrix Metalloproteinase Activatable Cell Penetrating Peptide Imaging Probes.
Sander M J van Duijnhoven, Marc S Robillard, Klaas Nicolay, Holger Grüll

Molecules· July 2015

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Novel analogs of antitumor agent calixarene 0118: Synthesis, cytotoxicity, click labeling with 2-[(18)F]fluoroethylazide, and in vivo evaluation.
Tilman Läppchen, Ruud P M Dings, Raffaella Rossin, Justine F Simon, Ton J Visser, Marc S Robillard

Eur J Med Chem· January 2015

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Pretargeted imaging using bioorthogonal chemistry in mice.
Raffaella Rossin, Marc S Robillard

Curr Opin Chem Biol· August 2014

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