Publications by authors named "Marc-Jan van Goethem"

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Notch signaling is a driver of glandular stem cell activity and regenerative migration after damage.
Davide Cinat, Rufina Maturi, Jeremy P Gunawan, Anne L Jellema-de Bruin, Laura Kracht, Marc-Jan van Goethem

EMBO J· November 2025

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IFN-I signaling enhances salivary gland stem and progenitor cell activity after irradiation.
Davide Cinat, Ryan van der Wal, Mirjam Baanstra, Abel Soto-Gamez, Rufina Maturi, Marc-Jan van Goethem

Sci Signal· November 2025

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Feasibility study of a compact proton-radiography system based on a scintillator screen.
Francesco Olivari, Marc-Jan van Goethem, Sytze Brandenburg, Emiel R van der Graaf

Phys Med· August 2025

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Development and validation of cost-effective multi-sample hypoxia chambers for proton ultra-high dose rate organoid irradiations.
Rutger Jan Cornelis de Koster, Jeremy Putra Gunawan, Hans Peters, Johan Bussink, Lara Barazzuol, Marc-Jan van Goethem

Clin Transl Radiat Oncol· July 2025

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Sparing of the Heart Facilitates Recovery From Cardiopulmonary Side Effects After Thoracic Irradiation.
Julia Wiedemann, Sai K Paruchuru, Lisette E den Boef, Uilke Brouwer, Herman H W Silljé, Marc-Jan van Goethem

Int J Radiat Oncol Biol Phys· January 2025

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Radiation-induced DNA double-strand breaks in cortisol exposed fibroblasts as quantified with the novel foci-integrated damage complexity score (FIDCS).
Wilhelmina E Radstake, Alessio Parisi, Silvana Miranda, Kiran Gautam, Randy Vermeesen, Marc-Jan van Goethem

Sci Rep· May 2024

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Proton therapy induces a local microglial neuroimmune response.
Daniëlle C Voshart, Myrthe Klaver, Yuting Jiang, Hilmar R J van Weering, Fleur van Buuren-Broek, Marc-Jan van Goethem

Radiother Oncol· April 2024

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Impact of proton therapy on the DNA damage induction and repair in hematopoietic stem and progenitor cells.
Simon Sioen, Oniecha Vanhove, Barbara Vanderstraeten, Carlos De Wagter, Monique Engelbrecht, Marc-Jan Van Goethem

Sci Rep· October 2023

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A Monte-Carlo-based study of a single-2D-detector proton-radiography system.
Francesco Olivari, Marc-Jan van Goethem, Sytze Brandenburg, Emiel R van der Graaf

Phys Med· August 2023

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The Effects of Combined Exposure to Simulated Microgravity, Ionizing Radiation, and Cortisol on the Wound Healing Process.
Wilhelmina E Radstake, Kiran Gautam, Silvana Miranda, Randy Vermeesen, Kevin Tabury, Marc-Jan van Goethem

Cells· January 2023

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Investigating the lateral dose response functions of point detectors in proton beams.
Jana Kretschmer, Leonie Brodbek, Hui Khee Looe, Emiel van der Graaf, Marc Jan van Goethem

Phys Med Biol· July 2022

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A simple microscopy setup for visualizing cellular responses to DNA damage at particle accelerator facilities.
Haibin Qian, Ron A Hoebe, Michel R Faas, Marc Jan van Goethem, Emiel R van der Graaf

Sci Rep· July 2021

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Feasibility of quasi-prompt PET-based range verification in proton therapy.
Ikechi Ozoemelam, Emiel van der Graaf, Marc-Jan van Goethem, Maciej Kapusta, Nan Zhang

Phys Med Biol· December 2020

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Validation of linear energy transfer computed in a Monte Carlo dose engine of a commercial treatment planning system.
Dirk Wagenaar, Linh T Tran, Arturs Meijers, Gabriel Guterres Marmitt, Kevin Souris, Marc-Jan van Goethem

Phys Med Biol· January 2020

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In vitro biological response of cancer and normal tissue cells to proton irradiation not affected by an added magnetic field.
Peter W Nagle, Marc-Jan van Goethem, Marco Kempers, Harry Kiewit, Antje Knopf

Radiother Oncol· August 2019

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Lack of DNA Damage Response at Low Radiation Doses in Adult Stem Cells Contributes to Organ Dysfunction.
Peter W Nagle, Nynke A Hosper, Lara Barazzuol, Anne L Jellema, Mirjam Baanstra, Marc-Jan van Goethem

Clin Cancer Res· December 2018

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Comparative study of the effects of different radiation qualities on normal human breast cells.
Dajana Juerß, Monique Zwar, Ulrich Giesen, Ralf Nolte, Stephan Kriesen, Marc-Jan van Goethem

Radiat Oncol· September 2017

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Improving proton therapy by metal-containing nanoparticles: nanoscale insights.
Thomas Schlathölter, Pierre Eustache, Erika Porcel, Daniela Salado, Lenka Stefancikova, Marc-Jan van Goethem

Int J Nanomedicine· October 2016

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The In Vitro Response of Tissue Stem Cells to Irradiation With Different Linear Energy Transfers.
Peter W Nagle, Nynke A Hosper, Emily M Ploeg, Marc-Jan van Goethem, Sytze Brandenburg

Int J Radiat Oncol Biol Phys· May 2016

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Proton Radiography With Timepix Based Time Projection Chambers.
Aleksandra K Biegun, Jan Visser, Tom Klaver, Nafiseh Ghazanfari, Marc-Jan van Goethem

IEEE Trans Med Imaging· April 2016

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Relative electron density determination using a physics based parameterization of photon interactions in medical DECT.
Joanne K van Abbema, Marc-Jan van Goethem, Marcel J W Greuter, Arjen van der Schaaf, Sytze Brandenburg

Phys Med Biol· May 2015

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High and low LET radiation differentially induce normal tissue damage signals.
Maarten Niemantsverdriet, Marc-Jan van Goethem, Reinier Bron, Wytse Hogewerf, Sytze Brandenburg

Int J Radiat Oncol Biol Phys· July 2012

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Development of a facility for high-precision irradiation of cells with carbon ions.
Marc-Jan van Goethem, Maarten Niemantsverdriet, Sytze Brandenburg, Johannes A Langendijk, Robert P Coppes

Med Phys· January 2011

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