Publications by authors named "Marcel Scheepstra"

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Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen.
Koen F W Hekking, Sergio Maroto, Kees van Kekem, Frank S Haasjes, Jack C Slootweg, Marcel Scheepstra

J Med Chem· February 2024

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Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists.
Femke A Meijer, Richard G Doveston, Rens M J M de Vries, Gaël M Vos, Alex A A Vos, Marcel Scheepstra

J Med Chem· January 2020

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Bivalent Ligands for Protein Degradation in Drug Discovery.
Marcel Scheepstra, Koen F W Hekking, Luc van Hijfte, Rutger H A Folmer

Comput Struct Biotechnol J· January 2019

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Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization.
Marcel Scheepstra, Sebastian A Andrei, Rens M J M de Vries, Femke A Meijer, Jian-Nong Ma

ACS Chem Neurosci· September 2017

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Designed Spiroketal Protein Modulation.
Marcel Scheepstra, Sebastian A Andrei, M Yagiz Unver, Anna K H Hirsch, Seppe Leysen

Angew Chem Int Ed Engl· May 2017

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Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor-Nuclear Receptor Related 1 Protein Dimer Activation.
Henrik Sundén, Anja Schäfer, Marcel Scheepstra, Seppe Leysen, Marcus Malo

J Med Chem· February 2016

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Identification of an allosteric binding site for RORγt inhibition.
Marcel Scheepstra, Seppe Leysen, Geert C van Almen, J Richard Miller, Jennifer Piesvaux

Nat Commun· December 2015

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Subtype-specific modulation of estrogen receptor-coactivator interaction by phosphorylation.
Inga M Tharun, Lidia Nieto, Christian Haase, Marcel Scheepstra, Mark Balk

ACS Chem Biol· February 2015

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A natural-product switch for a dynamic protein interface.
Marcel Scheepstra, Lidia Nieto, Anna K H Hirsch, Sascha Fuchs, Seppe Leysen

Angew Chem Int Ed Engl· June 2014

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Cucurbit[8]uril induced heterodimerization of methylviologen and naphthalene functionalized proteins.
Dana A Uhlenheuer, Jacqui F Young, Hoang D Nguyen, Marcel Scheepstra, Luc Brunsveld

Chem Commun (Camb)· June 2011

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