Publications by authors named "Marcela Mrhalova"

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Functional validation of somatic variability in and for prediction of platinum sensitivity and prognosis in epithelial ovarian carcinoma patients.
Al Obeed Allah Mohammad, Ali Esraa, Krus Ivona, Holý Petr, Haničinec Vojtěch

Cancer Biol Ther· December 2025

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Integrative miRNOMe profiling reveals the miR-195-5p-CHEK1 axis and its impact on luminal breast cancer outcomes.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová

Mol Oncol· November 2025

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A case series of newly described rare mesenchymal tumors of the knee and the role of molecular testing in their histopathological diagnosis.
Jan Balko, William Golas, Petr Skapa, Jaromir Hacek, Lenka Krskova, Marcela Mrhalova

Pathol Res Pract· November 2025

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Molecular impact of NOTCH signaling dysregulation on ovarian cancer progression, chemoresistance, and taxane response.
Kamila Koucka, Alzbeta Spalenkova, Karolina Seborova, Tereza Tesarova, Marie Ehrlichova, Marcela Mrhalova

Biomed Pharmacother· October 2025

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Targeted DNA sequencing of high-grade serous ovarian carcinoma reveals association of TP53 mutations with platinum resistance when combined with gene expression.
Petr Holý, Viktor Hlaváč, Karolína Šeborová, Simona Šůsová, Tereza Tesařová

Int J Cancer· July 2024

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Telomere length as a predictor of therapy response and survival in patients diagnosed with ovarian carcinoma.
Kristyna Tomasova, Karolina Seborova, Michal Kroupa, Josef Horak, Miriam Kavec, Marcela Mrhalova

Heliyon· July 2024

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Molecular Screening in Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma: Anaplastic Lymphoma Kinase Analysis, Next-Generation Sequencing Fusion Gene Detection, and T-Cell Receptor Immunoprofiling.
Marketa Kalinova, Marcela Mrhalova, Edita Kabickova, Michael Svaton, Aneta Skotnicova

Mod Pathol· March 2024

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Integrative analysis of mRNA and miRNA expression profiles and somatic variants in oxysterol signaling in early-stage luminal breast cancer.
Petr Holý, Veronika Brynychová, Karolína Šeborová, Vojtěch Haničinec, Renata Koževnikovová

Mol Oncol· October 2023

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Complex molecular profile of DNA repair genes in epithelial ovarian carcinoma patients with different sensitivity to platinum-based therapy.
Karolina Seborova, Viktor Hlavac, Petr Holy, Sunniva S Bjørklund, Thomas Fleischer, Marcela Mrhalova

Front Oncol· December 2022

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Whole-exome sequencing of epithelial ovarian carcinomas differing in resistance to platinum therapy.
Viktor Hlaváč, Petr Holý, Radka Václavíková, Lukáš Rob, Martin Hruda

Life Sci Alliance· October 2022

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Germline and somatic genetic variability of oxysterol-related genes in breast cancer patients with early disease of the luminal subtype.
Petr Holý, Viktor Hlaváč, Pavel Ostašov, Veronika Brynychová, Renata Koževnikovová

Biochimie· August 2022

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Determination of biological behavior of solitary fibrous tumors: correlation of expression of Ki-67, TPX2 and TERT mRNA subunit level and NAB2-STAT6 fusion compared to morphological aspects of SFTs.
Lenka Krsková, Igor Odintsov, Ondřej Fabián, Petra Hroudová, Marcela Mrhalová

Neoplasma· January 2022

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The Role of TRIP6, ABCC3 and CPS1 Expression in Resistance of Ovarian Cancer to Taxanes.
Karolina Seborova, Alzbeta Kloudova-Spalenkova, Kamila Koucka, Petr Holy, Marie Ehrlichova, Marcela Mrhalova

Int J Mol Sci· December 2021

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Next generation sequencing - a science tool or routine pathology?
Lenka Krsková, Markéta Kalinová, Tereza Němečková, Barbora Šípalová, Marcela Mrhalová

Cesk Patol· September 2021

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Development of high‑resolution melting analysis for ABCB1 promoter methylation: Clinical consequences in breast and ovarian carcinoma.
Radka Vaclavikova, Jovana Klajic, Veronika Brynychova, Katerina Elsnerova, Grethe I G Alnaes, Marcela Mrhalova

Oncol Rep· August 2019

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Expression of oxysterol pathway genes in oestrogen-positive breast carcinomas.
Alzbeta Kloudova, Veronika Brynychova, Radka Vaclavikova, David Vrana, Jiri Gatek, Marcela Mrhalova

Clin Endocrinol (Oxf)· June 2017

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A t(4;19) pediatric undifferentiated sarcoma with a novel variant of the CIC-DUX4 fusion transcript.
Lenka Krskova, Eva Stejskalova, Edita Kabickova, Marcela Mrhalova, Roman Kodet

Pathol Res Pract· March 2017

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Transcript expression and genetic variability analysis of caspases in breast carcinomas suggests CASP9 as the most interesting target.
Veronika Brynychova, Viktor Hlavac, Marie Ehrlichova, Radka Vaclavikova, Vlasta Nemcova-Furstova, Marcela Mrhalova

Clin Chem Lab Med· January 2017

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Genetic and functional analyses do not explain the association of high PRC1 expression with poor survival of breast carcinoma patients.
Veronika Brynychova, Marie Ehrlichova, Viktor Hlavac, Vlasta Nemcova-Furstova, Vaclav Pecha, Marcela Mrhalova

Biomed Pharmacother· October 2016

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The role of cytochromes p450 and aldo-keto reductases in prognosis of breast carcinoma patients.
Viktor Hlaváč, Veronika Brynychová, Radka Václavíková, Marie Ehrlichová, David Vrána

Medicine (Baltimore)· December 2014

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[A complex diagnostic approach in lymphomas: practical aspect in short case reports].
Markéta Kalinová, Marcela Mrhalová, Lenka Krsková, Helena Jungbauerová, Alena Kalfusová

Cesk Patol· July 2014

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[Soft tissue tumors - the view of the molecular biologist].
Lenka Krsková, Marcela Mrhalová, Markéta Kalinová, Vít Campr, Linda Capková

Cesk Patol· July 2014

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[Fluorescence in situ hybridization on histologic sections].
Marcela Mrhalová, Roman Kodet

Cesk Patol· October 2013

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The association of taxane resistance genes with the clinical course of ovarian carcinoma.
Marie Ehrlichova, Beatrice Mohelnikova-Duchonova, Jiri Hrdy, Veronika Brynychova, Marcela Mrhalova

Genomics· August 2013

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Importance of transcript levels of caspase-2 isoforms S and L for breast carcinoma progression.
Veronika Brynychová, Viktor Hlaváč, Marie Ehrlichová, Radka Václavíková, Václav Pecha

Future Oncol· March 2013

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