Publications by authors named "Marcella Nesi"

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Identification of unprecedented ATP-competitive choline kinase inhibitors.
Francesca Quartieri, Marcella Nesi, Nilla R Avanzi, Daniela Borghi, Elena Casale

Bioorg Med Chem Lett· November 2021

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Correction to Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
Maria Menichincheri, Elena Ardini, Paola Magnaghi, Nilla Avanzi, Patrizia Banfi, Marcella Nesi

J Med Chem· September 2019

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Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
Maria Menichincheri, Elena Ardini, Paola Magnaghi, Nilla Avanzi, Patrizia Banfi, Marcella Nesi

J Med Chem· April 2016

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Novel pyrrole carboxamide inhibitors of JAK2 as potential treatment of myeloproliferative disorders.
Maria Gabriella Brasca, Paola Gnocchi, Marcella Nesi, Nadia Amboldi, Nilla Avanzi

Bioorg Med Chem· May 2015

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Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors.
Maria Gabriella Brasca, Marcella Nesi, Nilla Avanzi, Dario Ballinari, Tiziano Bandiera

Bioorg Med Chem· September 2014

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Crystal structures of anaplastic lymphoma kinase in complex with ATP competitive inhibitors.
Roberto T Bossi, M Beatrice Saccardo, Elena Ardini, Maria Menichincheri, Luisa Rusconi, Marcella Nesi

Biochemistry· August 2010

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Optimization of 6,6-dimethyl pyrrolo[3,4-c]pyrazoles: Identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing.
Maria Gabriella Brasca, Clara Albanese, Rachele Alzani, Raffaella Amici, Nilla Avanzi, Marcella Nesi

Bioorg Med Chem· March 2010

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6-Substituted pyrrolo[3,4-c]pyrazoles: an improved class of CDK2 inhibitors.
Maria Gabriella Brasca, Clara Albanese, Raffaella Amici, Dario Ballinari, Luca Corti, Marcella Nesi

ChemMedChem· June 2007

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A practical synthesis of the major 3-hydroxy-2-pyrrolidinone metabolite of a potent CDK2/cyclin A inhibitor.
Marcella Nesi, Daniela Borghi, Maria Gabriella Brasca, Francesco Fiorentini, Paolo Pevarello

Bioorg Med Chem Lett· June 2006

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3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 2. Lead optimization.
Paolo Pevarello, Maria Gabriella Brasca, Paolo Orsini, Gabriella Traquandi, Antonio Longo, Marcella Nesi

J Med Chem· April 2005

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