Publications by authors named "Marcella Rocchetti"

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YAP1 reactivation in cardiomyocytes following ECM remodelling contributes to the development of contractile force and sarcomere maturation.
Vladimir Vinarsky, Stefania Pagliari, Bacel Aldabash, Fabiana Martino, Cristina Mazzotti, Marcella Rocchetti

Cell Death Discov· November 2025

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Hypokalemia and bradycardia unmask the loss-of-function phenotype of a Brugada Syndrome SCN5A mutation.
Anthony Frosio, Procolo Marchese, Giorgia Bertoli, David Molla, Martina Arici, Marcella Rocchetti

Europace· July 2025

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Development of Small-molecule SERCA2a Stimulators: A Novel Class of Ino-lusitropic Agents.
Antonio Zaza, Marcella Rocchetti

Eur Cardiol· June 2025

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Selective SERCA2a activator as a candidate for chronic heart failure therapy.
Martina Arici, Shih-Che Hsu, Mara Ferrandi, Paolo Barassi, Carlotta Ronchi, Marcella Rocchetti

J Transl Med· January 2024

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A dynamic clamping approach using in silico IK1 current for discrimination of chamber-specific hiPSC-derived cardiomyocytes.
Claudia Altomare, Chiara Bartolucci, Luca Sala, Carolina Balbi, Jacopo Burrello, Marcella Rocchetti

Commun Biol· March 2023

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Istaroxime Metabolite PST3093 Selectively Stimulates SERCA2a and Reverses Disease-Induced Changes in Cardiac Function.
Martina Arici, Mara Ferrandi, Paolo Barassi, Shih-Che Hsu, Eleonora Torre, Marcella Rocchetti

J Pharmacol Exp Ther· January 2023

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Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging.
Edoardo Lazzarini, Alessandra Maria Lodrini, Martina Arici, Sara Bolis, Sara Vagni, Marcella Rocchetti

Theranostics· July 2022

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Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure.
Andrea Luraghi, Mara Ferrandi, Paolo Barassi, Martina Arici, Shih-Che Hsu, Marcella Rocchetti

J Med Chem· May 2022

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Liraglutide preserves CD34 stem cells from dysfunction Induced by high glucose exposure.
Annalisa Sforza, Vera Vigorelli, Erica Rurali, Gianluca Lorenzo Perrucci, Elisa Gambini, Marcella Rocchetti

Cardiovasc Diabetol· April 2022

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SERCA2a stimulation by istaroxime improves intracellular Ca2+ handling and diastolic dysfunction in a model of diabetic cardiomyopathy.
Eleonora Torre, Martina Arici, Alessandra Maria Lodrini, Mara Ferrandi, Paolo Barassi, Marcella Rocchetti

Cardiovasc Res· March 2022

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Generation and characterization of the human induced pluripotent stem cell (hiPSC) line NCUFi001-A from a patient carrying KCNQ1 G314S mutation.
Luca Lavra, Fiorenza Magi, Alessandra Ulivieri, Alessandra Morgante, Marianna Paulis, Marcella Rocchetti

Stem Cell Res· July 2021

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Targeting GRP receptor: Design, synthesis and preliminary biological characterization of new non-peptide antagonists of bombesin.
Alessandro Palmioli, Gabriella Nicolini, Farida Tripodi, Alexandre Orsato, Cecilia Ceresa, Marcella Rocchetti

Bioorg Chem· April 2021

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Structural and Electrophysiological Changes in a Model of Cardiotoxicity Induced by Anthracycline Combined With Trastuzumab.
Claudia Altomare, Alessandra Maria Lodrini, Giuseppina Milano, Vanessa Biemmi, Edoardo Lazzarini, Marcella Rocchetti

Front Physiol· April 2021

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MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes.
Yee-Ki Lee, Luca Sala, Manuela Mura, Marcella Rocchetti, Matteo Pedrazzini

Cardiovasc Res· February 2021

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NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis.
Carlotta Ronchi, Joyce Bernardi, Manuela Mura, Manuela Stefanello, Beatrice Badone, Marcella Rocchetti

Cardiovasc Res· January 2021

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Human iPSC modelling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes.
Patrizia Benzoni, Giulia Campostrini, Sara Landi, Valeria Bertini, Eleonora Marchina, Marcella Rocchetti

Cardiovasc Res· May 2020

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Human Induced Pluripotent Stem Cells Derived from a Cardiac Somatic Source: Insights for an In-Vitro Cardiomyocyte Platform.
Alessandra Maria Lodrini, Lucio Barile, Marcella Rocchetti, Claudia Altomare

Int J Mol Sci· January 2020

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Action potential contour contributes to species differences in repolarization response to β-adrenergic stimulation.
Luca Sala, Bence Hegyi, Chiara Bartolucci, Claudia Altomare, Marcella Rocchetti

Europace· September 2018

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Role of the β-adrenergic receptor subtype in catecholamine-induced myocardial remodeling.
Gizem Kayki Mutlu, Ebru Arioglu Inan, Irem Karaomerlioglu, V Melih Altan, Nilgun Yersal, Marcella Rocchetti

Mol Cell Biochem· September 2018

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Tissue specificity of mitochondrial adaptations in rats after 4 weeks of normobaric hypoxia.
Alessandra Ferri, Alice Panariti, Giuseppe Miserocchi, Marcella Rocchetti, Gaia Buoli Comani

Eur J Appl Physiol· August 2018

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Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Marcella Rocchetti, Luca Sala, Lisa Dreizehnter, Lia Crotti, Daniel Sinnecker

Cardiovasc Res· April 2017

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Late sodium current and intracellular ionic homeostasis in acute ischemia.
Carlotta Ronchi, Eleonora Torre, Riccardo Rizzetto, Joyce Bernardi, Marcella Rocchetti

Basic Res Cardiol· March 2017

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Peptidomimetic Targeting of Cavβ2 Overcomes Dysregulation of the L-Type Calcium Channel Density and Recovers Cardiac Function.
Francesca Rusconi, Paola Ceriotti, Michele Miragoli, Pierluigi Carullo, Nicolò Salvarani, Marcella Rocchetti

Circulation· August 2016

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Respiratory metabolism and calorie restriction relieve persistent endoplasmic reticulum stress induced by calcium shortage in yeast.
Stefano Busti, Valeria Mapelli, Farida Tripodi, Rossella Sanvito, Fulvio Magni, Marcella Rocchetti

Sci Rep· June 2016

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IKr Impact on Repolarization and Its Variability Assessed by Dynamic Clamp.
Claudia Altomare, Chiara Bartolucci, Luca Sala, Joyce Bernardi, Gaspare Mostacciuolo, Marcella Rocchetti

Circ Arrhythm Electrophysiol· October 2015

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