Publications by authors named "Marcin Ratajewski"

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Identification of a Novel Indolizine RORγT Inverse Agonist Using the AI-Driven Drug Design Platform.
Rafał A Bachorz, Joanna Pastwińska, Michael S Lawless, David W Miller, Anna Sałkowska, Marcin Ratajewski

ACS Med Chem Lett· July 2025

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Staphylococcus aureus α-hemolysin induces DNA methylation changes in human Th1 cells.
Iwona Karwaciak, Joanna Pastwińska, Anna Sałkowska, Kaja Karaś, Marta Sobalska-Kwapis, Marcin Ratajewski

Immunol Res· June 2025

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The cyclin-dependent kinase inhibitor AT7519 is a human RORγt agonist.
Kaja Karaś, Joanna Pastwińska, Anna Sałkowska, Iwona Karwaciak, Rafał A Bachorz, Marcin Ratajewski

Immunol Cell Biol· March 2025

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IL-17B Inhibits Hepatocellular Carcinoma Cell Proliferation.
Joanna Pastwińska, Iwona Karwaciak, Kaja Karaś, Daria Grabarczyk, Anna Sałkowska, Marcin Ratajewski

Arch Immunol Ther Exp (Warsz)· January 2025

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Epigenetic regulation of the human gene.
Kaja Karaś, Joanna Pastwińska, Anna Sałkowska, Iwona Karwaciak, Marcin Ratajewski

Biochem Biophys Rep· December 2024

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Evaluation of the activity of cardiac glycosides on RORγ and RORγT nuclear receptors.
Iwona Karwaciak, Joanna Pastwińska, Anna Sałkowska, Rafał A Bachorz, Marcin Ratajewski

Arch Biochem Biophys· September 2024

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α-Hemolysin from Staphylococcus aureus Changes the Epigenetic Landscape of Th17 Cells.
Joanna Pastwińska, Iwona Karwaciak, Kaja Karaś, Anna Sałkowska, Katarzyna Chałaśkiewicz, Marcin Ratajewski

Immunohorizons· September 2024

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QSPRmodeler - An open source application for molecular predictive analytics.
Rafał A Bachorz, Damian Nowak, Marcin Ratajewski

Front Bioinform· September 2024

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RORγT agonists as immune modulators in anticancer therapy.
Joanna Pastwińska, Iwona Karwaciak, Kaja Karaś, Rafał A Bachorz, Marcin Ratajewski

Biochim Biophys Acta Rev Cancer· November 2023

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The application of machine learning methods to the prediction of novel ligands for ROR/RORT receptors.
Rafał A Bachorz, Joanna Pastwińska, Damian Nowak, Kaja Karaś, Iwona Karwaciak, Marcin Ratajewski

Comput Struct Biotechnol J· October 2023

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Anti-hepatocellular carcinoma activity of the cyclin-dependent kinase inhibitor AT7519.
Kaja Karaś, Iwona Karwaciak, Katarzyna Chałaśkiewicz, Anna Sałkowska, Joanna Pastwińska, Marcin Ratajewski

Biomed Pharmacother· August 2023

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Trichostatin A inhibits expression of the human SLC2A5 gene via SNAI1/SNAI2 transcription factors and sensitizes colon cancer cells to platinum compounds.
Katarzyna Chałaśkiewicz, Kaja Karaś, Małgorzata Zakłos-Szyda, Iwona Karwaciak, Joanna Pastwińska, Marcin Ratajewski

Eur J Pharmacol· June 2023

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Targeting EGFR in melanoma - The sea of possibilities to overcome drug resistance.
Joanna Pastwińska, Kaja Karaś, Iwona Karwaciak, Marcin Ratajewski

Biochim Biophys Acta Rev Cancer· July 2022

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Chlorpromazine, a Clinically Approved Drug, Inhibits SARS-CoV-2 Nucleocapsid-Mediated Induction of IL-6 in Human Monocytes.
Iwona Karwaciak, Kaja Karaś, Anna Sałkowska, Joanna Pastwińska, Marcin Ratajewski

Molecules· June 2022

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Hypoxia modulates human mast cell adhesion to hyaluronic acid.
Joanna Pastwińska, Aurelia Walczak-Drzewiecka, Elżbieta Kozłowska, Enjuro Harunari, Marcin Ratajewski

Immunol Res· April 2022

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Cyanobacterial cell-wall components as emerging environmental toxicants - detection and holistic monitoring by cellular signaling biosensors.
Ilona Gągała-Borowska, Iwona Karwaciak, Dorota Jaros, Marcin Ratajewski, Mikołaj Kokociński

Sci Total Environ· February 2022

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Identification of Corosolic and Oleanolic Acids as Molecules Antagonizing the Human RORγT Nuclear Receptor Using the Calculated Fingerprints of the Molecular Similarity.
Joanna Pastwińska, Kaja Karaś, Anna Sałkowska, Iwona Karwaciak, Katarzyna Chałaśkiewicz, Marcin Ratajewski

Int J Mol Sci· February 2022

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Phenolics-Rich Extracts of Dietary Plants as Regulators of Fructose Uptake in Caco-2 Cells via GLUT5 Involvement.
Małgorzata Zakłos-Szyda, Nina Pietrzyk, Agnieszka Kowalska-Baron, Adriana Nowak, Katarzyna Chałaśkiewicz, Marcin Ratajewski

Molecules· August 2021

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Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism.
Iwona Karwaciak, Anna Sałkowska, Kaja Karaś, Jarosław Dastych, Marcin Ratajewski

Int J Mol Sci· May 2021

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Recombinant immunotoxin targeting GPC3 is cytotoxic to H446 small cell lung cancer cells.
Ewelina Rodakowska, Aurelia Walczak-Drzewiecka, Marta Borowiec, Michal Gorzkiewicz, Joanna Grzesik, Marcin Ratajewski

Oncol Lett· March 2021

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Nucleocapsid and Spike Proteins of the Coronavirus SARS-CoV-2 Induce in Monocytes and Macrophages-Potential Implications for Cytokine Storm Syndrome.
Iwona Karwaciak, Anna Sałkowska, Kaja Karaś, Jarosław Dastych, Marcin Ratajewski

Vaccines (Basel)· January 2021

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Hypoxia regulates human mast cell adhesion to fibronectin via the PI3K/AKT signaling pathway.
Joanna Pastwińska, Aurelia Walczak-Drzewiecka, Magdalena Łukasiak, Marcin Ratajewski, Jarosław Dastych

Cell Adh Migr· December 2020

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SARS-CoV-2 Proteins Induce in Th1 Lymphocytes Generated from CD4+ Cells from Healthy, Unexposed Polish Donors.
Anna Sałkowska, Iwona Karwaciak, Kaja Karaś, Jarosław Dastych, Marcin Ratajewski

Vaccines (Basel)· November 2020

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Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells.
Magdalena Niemira, Barbara Borowa-Mazgaj, Samuel B Bader, Adrianna Moszyńska, Marcin Ratajewski

Biomedicines· August 2020

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Identification of Novel Molecular Markers of Human Th17 Cells.
Anna Sałkowska, Kaja Karaś, Iwona Karwaciak, Aurelia Walczak-Drzewiecka, Mariusz Krawczyk, Marcin Ratajewski

Cells· July 2020

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