Publications by authors named "Marco Linari"

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Multiple pathways of the actin-myosin cycle in energy transduction and the release of orthophosphate in muscle.
Marco Caremani, Irene Pertici, Ilaria Morotti, Pasquale Bianco, Massimo Reconditi, Marco Linari

Front Physiol· November 2025

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Creatine transporter (SLC6A8) knockout mice exhibit reduced muscle performance, disrupted mitochondrial Ca homeostasis, and severe muscle atrophy.
Irene Pertici, Donato D'Angelo, Denis Vecellio Reane, Massimo Reconditi, Ilaria Morotti, Marco Linari

Cell Death Dis· February 2025

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The Mechanism of Modulation of Cardiac Force by Temperature.
Ilaria Morotti, Matteo Marcello, Giulia Sautariello, Irene Pertici, Pasquale Bianco, Marco Linari

Int J Mol Sci· January 2025

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An integrated picture of the structural pathways controlling the heart performance.
Ilaria Morotti, Marco Caremani, Matteo Marcello, Irene Pertici, Caterina Squarci, Marco Linari

Proc Natl Acad Sci U S A· December 2024

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Force and kinetics of fast and slow muscle myosin determined with a synthetic sarcomere-like nanomachine.
Valentina Buonfiglio, Irene Pertici, Matteo Marcello, Ilaria Morotti, Marco Caremani, Marco Linari

Commun Biol· March 2024

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Sarcomere level mechanics of the fast skeletal muscle of the medaka fish larva.
Matteo Marcello, Viviana Cetrangolo, Ilaria Morotti, Caterina Squarci, Marco Caremani, Marco Linari

Am J Physiol Cell Physiol· February 2024

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Dependence of myosin filament structure on intracellular calcium concentration in skeletal muscle.
Marco Caremani, Luca Fusi, Massimo Reconditi, Gabriella Piazzesi, Theyencheri Narayanan, Marco Linari

J Gen Physiol· December 2023

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Matching Mechanics and Energetics of Muscle Contraction Suggests Unconventional Chemomechanical Coupling during the Actin-Myosin Interaction.
Irene Pertici, Lorenzo Bongini, Marco Caremani, Massimo Reconditi, Marco Linari

Int J Mol Sci· August 2023

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Titin activates myosin filaments in skeletal muscle by switching from an extensible spring to a mechanical rectifier.
Caterina Squarci, Pasquale Bianco, Massimo Reconditi, Irene Pertici, Marco Caremani, Marco Linari

Proc Natl Acad Sci U S A· February 2023

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The force of the myosin motor sets cooperativity in thin filament activation of skeletal muscles.
Marco Caremani, Matteo Marcello, Ilaria Morotti, Irene Pertici, Caterina Squarci, Marco Linari

Commun Biol· November 2022

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Myosin motors that cannot bind actin leave their folded OFF state on activation of skeletal muscle.
Massimo Reconditi, Elisabetta Brunello, Luca Fusi, Marco Linari, Vincenzo Lombardi

J Gen Physiol· November 2021

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Dependence of thick filament structure in relaxed mammalian skeletal muscle on temperature and interfilament spacing.
Marco Caremani, Luca Fusi, Marco Linari, Massimo Reconditi, Gabriella Piazzesi

J Gen Physiol· March 2021

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Orthophosphate increases the efficiency of slow muscle-myosin isoform in the presence of omecamtiv mecarbil.
Serena Governali, Marco Caremani, Cristina Gallart, Irene Pertici, Ger Stienen, Marco Linari

Nat Commun· July 2020

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Straightening Out the Elasticity of Myosin Cross-Bridges.
Marco Linari, Gabriella Piazzesi, Irene Pertici, Jody A Dantzig, Yale E Goldman

Biophys J· March 2020

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Myopalladin promotes muscle growth through modulation of the serum response factor pathway.
Maria Carmela Filomena, Daniel L Yamamoto, Marco Caremani, Vinay K Kadarla, Giuseppina Mastrototaro, Marco Linari

J Cachexia Sarcopenia Muscle· February 2020

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Low temperature traps myosin motors of mammalian muscle in a refractory state that prevents activation.
Marco Caremani, Elisabetta Brunello, Marco Linari, Luca Fusi, Thomas C Irving

J Gen Physiol· November 2019

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Thick Filament Length Changes in Muscle Have Both Elastic and Structural Components.
Massimo Reconditi, Luca Fusi, Marco Caremani, Elisabetta Brunello, Marco Linari

Biophys J· March 2019

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Inotropic interventions do not change the resting state of myosin motors during cardiac diastole.
Marco Caremani, Francesca Pinzauti, Joseph D Powers, Serena Governali, Theyencheri Narayanan, Marco Linari

J Gen Physiol· January 2019

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The force and stiffness of myosin motors in the isometric twitch of a cardiac trabecula and the effect of the extracellular calcium concentration.
Francesca Pinzauti, Irene Pertici, Massimo Reconditi, Theyencheri Narayanan, Ger J M Stienen, Marco Linari

J Physiol· July 2018

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Thick Filament Mechano-Sensing in Skeletal and Cardiac Muscles: A Common Mechanism Able to Adapt the Energetic Cost of the Contraction to the Task.
Gabriella Piazzesi, Marco Caremani, Marco Linari, Massimo Reconditi, Vincenzo Lombardi

Front Physiol· June 2018

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Myosin filament activation in the heart is tuned to the mechanical task.
Massimo Reconditi, Marco Caremani, Francesca Pinzauti, Joseph D Powers, Theyencheri Narayanan, Marco Linari

Proc Natl Acad Sci U S A· March 2017

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Size and speed of the working stroke of cardiac myosin in situ.
Marco Caremani, Francesca Pinzauti, Massimo Reconditi, Gabriella Piazzesi, Ger J M Stienen, Marco Linari

Proc Natl Acad Sci U S A· March 2016

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Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments.
Marco Linari, Elisabetta Brunello, Massimo Reconditi, Luca Fusi, Marco Caremani

Nature· December 2015

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Force and number of myosin motors during muscle shortening and the coupling with the release of the ATP hydrolysis products.
Marco Caremani, Luca Melli, Mario Dolfi, Vincenzo Lombardi, Marco Linari

J Physiol· August 2015

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The contributions of filaments and cross-bridges to sarcomere compliance in skeletal muscle.
Elisabetta Brunello, Marco Caremani, Luca Melli, Marco Linari, Manuel Fernandez-Martinez

J Physiol· September 2014

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