Publications by authors named "Marco Piccinini"

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Fluorescent Isostere () of the Carboxylate: Design of DHODH Fluorescent Inhibitors as Proof of Concept.
Stefano Sainas, Elena Martino, Claudio Garino, Paola Circosta, Anna Luganini, Marco Piccinini

J Med Chem· July 2025

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AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib.
Barbara Buccinnà, Cristina Ramondetti, Marco Piccinini

Biochem Pharmacol· October 2022

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Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-]pyridine Scaffold: SAR of the Aryloxyaryl Moiety.
Stefano Sainas, Marta Giorgis, Paola Circosta, Giulio Poli, Marta Alberti, Marco Piccinini

J Med Chem· October 2022

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Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-]pyridine Scaffold: SAR of the Biphenyl Moiety.
Stefano Sainas, Marta Giorgis, Paola Circosta, Valentina Gaidano, Davide Bonanni, Marco Piccinini

J Med Chem· May 2021

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Correction to Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors.
Stefano Sainas, Agnese C Pippione, Elisa Lupino, Marta Giorgis, Paola Circosta, Marco Piccinini

J Med Chem· February 2019

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Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors.
Stefano Sainas, Agnese C Pippione, Elisa Lupino, Marta Giorgis, Paola Circosta, Marco Piccinini

J Med Chem· July 2018

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-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK.
Agnese C Pippione, Stefano Sainas, Antonella Federico, Elisa Lupino, Marco Piccinini

Medchemcomm· June 2018

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4-Hydroxy--[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade.
Agnese C Pippione, Antonella Federico, Alex Ducime, Stefano Sainas, Donatella Boschi, Marco Piccinini

Medchemcomm· September 2017

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Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds.
Stefano Sainas, Agnese C Pippione, Marta Giorgis, Elisa Lupino, Parveen Goyal, Marco Piccinini

Eur J Med Chem· March 2017

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Numerical prediction of peri-implant bone adaptation: Comparison of mechanical stimuli and sensitivity to modeling parameters.
Marco Piccinini, Joel Cugnoni, John Botsis, Patrick Ammann, Anselm Wiskott

Med Eng Phys· November 2016

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Peri-implant bone adaptations to overloading in rat tibiae: experimental investigations and numerical predictions.
Marco Piccinini, Joel Cugnoni, John Botsis, Patrick Ammann, Anselm Wiskott

Clin Oral Implants Res· November 2016

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Gas phase stabiliser-free production of hydrogen peroxide using supported gold-palladium catalysts.
Adeeba Akram, Simon J Freakley, Christian Reece, Marco Piccinini, Greg Shaw

Chem Sci· September 2016

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Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27(KIP1) as a consequence of c-Abl inhibition.
Elisa Lupino, Cristina Ramondetti, Barbara Buccinnà, Marco Piccinini

Biochem Pharmacol· November 2014

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Influence of gait loads on implant integration in rat tibiae: experimental and numerical analysis.
Marco Piccinini, Joel Cugnoni, John Botsis, Patrick Ammann, Anselm Wiskott

J Biomech· October 2014

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Factors affecting subject-specific finite element models of implant-fitted rat bone specimens: critical analysis of a technical protocol.
Marco Piccinini, Joel Cugnoni, John Botsis, Giovanna Zacchetti, Patrick Ammann

Comput Methods Biomech Biomed Engin· September 2014

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Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases.
Giovanni De Marco, Annarosa Lomartire, Giorgia Mandili, Elisa Lupino, Barbara Buccinnà, Marco Piccinini

Biochim Biophys Acta· April 2014

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The direct synthesis of hydrogen peroxide using platinum-promoted gold-palladium catalysts.
Jennifer K Edwards, James Pritchard, Li Lu, Marco Piccinini, Greg Shaw

Angew Chem Int Ed Engl· February 2014

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IκB kinase β is required for activation of NF-κB and AP-1 in CD3/CD28-stimulated primary CD4(+) T cells.
Elisa Lupino, Cristina Ramondetti, Marco Piccinini

J Immunol· March 2012

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Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations.
Giovanni De Marco, Elisa Lupino, Andrea Calvo, Cristina Moglia, Barbara Buccinnà, Marco Piccinini

Acta Neuropathol· May 2011

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Nitrooxyacyl derivatives of salicylic acid: aspirin-like molecules that covalently inactivate cyclooxygenase-1.
Clara Cena, Paolo Tosco, Elisabetta Marini, Loretta Lazzarato, Marco Piccinini

ChemMedChem· March 2011

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Direct synthesis of hydrogen peroxide and benzyl alcohol oxidation using Au-Pd catalysts prepared by sol immobilization.
James Pritchard, Lokesh Kesavan, Marco Piccinini, Qian He, Ramchandra Tiruvalam

Langmuir· November 2010

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In CD28-costimulated human naïve CD4+ T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms.
Elisa Lupino, Barbara Buccinnà, Cristina Ramondetti, Annarosa Lomartire, Giovanni De Marco, Marco Piccinini

Immunology· October 2010

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Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders.
Marco Piccinini, Federica Scandroglio, Simona Prioni, Barbara Buccinnà, Nicoletta Loberto

Mol Neurobiol· June 2010

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N-CAM dysfunction and unexpected accumulation of PSA-NCAM in brain of adult-onset autosomal-dominant leukodystrophy.
Marco Piccinini, Barbara Buccinnà, Giovanni De Marco, Elisa Lupino, Cristina Ramondetti

Brain Pathol· March 2010

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Effect of the reaction conditions on the performance of Au-Pd/TiO(2) catalyst for the direct synthesis of hydrogen peroxide.
Marco Piccinini, Edwin Ntainjua, Jennifer K Edwards, Albert F Carley, Jacob A Moulijn

Phys Chem Chem Phys· March 2010

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