Publications by authors named "Marcus M Fischer"

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RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.
Marcus M Fischer, V Pete Yeung, Fiore Cattaruzza, Rajaa Hussein, Wan-Ching Yen

Sci Rep· November 2017

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WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death.
Marcus M Fischer, Belinda Cancilla, V Pete Yeung, Fiore Cattaruzza, Cecile Chartier

Sci Adv· June 2017

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Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Jing Shan Lim, Alvaro Ibaseta, Marcus M Fischer, Belinda Cancilla, Gilbert O'Young

Nature· May 2017

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Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates β-Catenin Signaling and Tumorigenesis in Multiple Cancer Types.
Cecile Chartier, Janak Raval, Fumiko Axelrod, Chris Bond, Jennifer Cain, Marcus M Fischer

Cancer Res· February 2016

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Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain

Clin Cancer Res· May 2015

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Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-Notch signaling in both tumor and vasculature cells.
Wan-Ching Yen, Marcus M Fischer, Mark Hynes, Jingjiang Wu, Edward Kim

Clin Cancer Res· October 2012

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