Publications by authors named "Margaret Torrence"

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mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species.
Aaron M Hosios, Meghan E Wilkinson, Molly C McNamara, Krystle C Kalafut, Margaret E Torrence

Nat Metab· December 2022

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Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex.
Molly C McNamara, Aaron M Hosios, Margaret E Torrence, Ting Zhao, Cameron Fraser

iScience· November 2022

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The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth.
Sandra Schrötter, Christopher J Yuskaitis, Michael R MacArthur, Sarah J Mitchell, Aaron M Hosios, Margaret E Torrence

Cell Rep· May 2022

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The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals.
Margaret E Torrence, Michael R MacArthur, Aaron M Hosios, Alexander J Valvezan, John M Asara

Elife· March 2021

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IMPDH inhibitors for antitumor therapy in tuberous sclerosis complex.
Alexander J Valvezan, Molly C McNamara, Spencer K Miller, Margaret E Torrence, John M Asara

JCI Insight· April 2020

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mTORC1 suppresses PIM3 expression via miR-33 encoded by the SREBP loci.
Ilana Kelsey, Marie Zbinden, Vanessa Byles, Margaret Torrence, Brendan D Manning

Sci Rep· November 2017

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Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.
Orianne Olivares, Jared R Mayers, Victoire Gouirand, Margaret E Torrence, Tristan Gicquel

Nat Commun· July 2017

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Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Jared R Mayers, Margaret E Torrence, Laura V Danai, Thales Papagiannakopoulos, Shawn M Davidson

Science· September 2016

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Circulating Metabolites and Survival Among Patients With Pancreatic Cancer.
Chen Yuan, Clary B Clish, Chen Wu, Jared R Mayers, Peter Kraft, Margaret E Torrence

J Natl Cancer Inst· June 2016

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Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.
Jared R Mayers, Chen Wu, Clary B Clish, Peter Kraft, Margaret E Torrence

Nat Med· October 2014

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