Publications by authors named "Margo Orlen"

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T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma.
Margo Orlen, William P Vostrejs, Rina Sor, Jayne C McDevitt, Samantha B Kemp

Cancer Discov· August 2025

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Multimetric MRI Captures Early Response and Acquired Resistance of Pancreatic Cancer to KRAS Inhibitor Therapy.
Mamta Gupta, Hoon Choi, Samantha B Kemp, Emma E Furth, Stephen Pickup, Margo Orlen

Clin Cancer Res· July 2025

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Multimetric MRI Captures Early Response and Acquired Resistance of Pancreatic Cancer to KRAS Inhibitor Therapy.
Mamta Gupta, Hoon Choi, Samantha B Kemp, Emma E Furth, Stephen Pickup, Margo Orlen

bioRxiv· April 2025

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Author Correction: Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Alvaro Curiel-Garcia, A Cole Edwards, Margo Orlen

Nature· November 2024

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Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Alvaro Curiel-Garcia, A Cole Edwards, Margo Orlen

Nature· May 2024

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N-glycosylation by Mgat5 imposes a targetable constraint on immune-mediated tumor clearance.
Erin E Hollander, Rosemary E Flock, Jayne C McDevitt, William P Vostrejs, Sydney L Campbell, Margo I Orlen

JCI Insight· May 2024

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Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
Urszula N Wasko, Jingjing Jiang, Alvaro Curiel-Garcia, Yingyun Wang, Bianca Lee, Margo Orlen

bioRxiv· December 2023

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Translational regulation of TFH cell differentiation and autoimmune pathogenesis.
Preeyam S Patel, Sandra Pérez-Baos, Beth Walters, Margo Orlen, Angelina Volkova

Sci Adv· June 2022

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The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation.
Thomas F Pack, Margo I Orlen, Caroline Ray, Sean M Peterson, Marc G Caron

J Biol Chem· April 2018

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