Publications by authors named "Margot DeBot"

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Endothelial Cell Calcium Influx Mediates Trauma-induced Endothelial Permeability.
Terry R Schaid, Sanchayita Mitra, Preston Stafford, Margot DeBot, Otto Thielen

Ann Surg· April 2025

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Cytoprotective 3K3A-activated protein C and plasma: A comparison of therapeutics for the endotheliopathy of trauma.
Otto Thielen, Preston Stafford, Margot Debot, Marguerite Kelher, Sanchayita Mitra

J Trauma Acute Care Surg· January 2025

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Trauma-induced dysfibrinogenemia: the von Clauss assay does not accurately measure fibrinogen levels after injury.
Margot DeBot, Christopher Erickson, Terry Schaid, Ian LaCroix, Ernest E Moore

Blood Vessel Thromb Hemost· September 2024

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Mitigation of trauma-induced endotheliopathy by activated protein C: A potential therapeutic for postinjury thromboinflammation.
Otto Thielen, Sanchayita Mitra, Margot Debot, Terry Schaid, William Hallas

J Trauma Acute Care Surg· January 2024

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Bradykinin release following trauma and hemorrhagic shock causes pulmonary alveolar leak in a rodent model.
Andrew Eitel, Ernest E Moore, Marguerite R Kelher, Mitchell J Cohen, Daniel Kissau, Margot Debot

J Trauma Acute Care Surg· October 2023

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Low-Dose Heparin Infusion as Venous Thromboembolism Chemoprophylaxis in Patients With Blunt Cerebrovascular Injury.
Gregory R Stettler, Joshua J Sumislawski, Margot Debot, Ernest E Moore, Clay Cothren Burlew

J Surg Res· June 2023

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REBOA for the Treatment of Blast Polytrauma: Zone 3 Provides Cerebral Perfusion, Attenuates Organ Dysfunction and Reperfusion Coagulopathy Compared to Zone 1 in a Swine Model.
Alexis L Cralley, Ernest E Moore, Angela Sauaia, Pedro H Carani, Terry R Schaid, Margot DeBot

J Trauma Acute Care Surg· May 2023

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OUTCOMES FOLLOWING ZONE 3 AND ZONE 1 AORTIC OCCLUSION FOR THE TREATMENT OF BLUNT PELVIC INJURIES.
Alexis L Cralley, Ernest E Moore, Joseph Dubose, Megan L Brenner, Terry R Schaid, Margot DeBot

Shock· May 2023

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Platelet and cryoprecipitate transfusions from female donors improve coagulopathy in vitro.
Margot DeBot, Christopher Erickson, Marguerite Kelher, Terry R Schaid, Ernest E Moore

J Trauma Acute Care Surg· April 2023

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A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player.
Terry R Schaid, Ian LaCroix, Kirk C Hansen, Angelo D'Alessandro, Ernest E Moore, Margot DeBot

J Trauma Acute Care Surg· March 2023

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TRAUMA INDUCES INTRAVASCULAR HEMOLYSIS, EXACERBATED BY RED BLOOD CELL TRANSFUSION AND ASSOCIATED WITH DISRUPTED ARGININE-NITRIC OXIDE METABOLISM.
Terry R Schaid, Mitchell J Cohen, Angelo D'Alessandro, Christopher C Silliman, Ernest E Moore, Margot DeBot

Shock· January 2023

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BLOOD TYPE O IS A RISK FACTOR FOR HYPERFIBRINOLYSIS AND MASSIVE TRANSFUSION AFTER SEVERE INJURY.
Margot DeBot, Andrew P Eitel, Ernest E Moore, Angela Sauaia, Patrick Lutz

Shock· December 2022

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SHOCK INDUCES ENDOTHELIAL PERMEABILITY AFTER TRAUMA THROUGH INCREASED ACTIVATION OF RHOA GTPASE.
Margot DeBot, Sanchayita Mitra, Patrick Lutz, Terry R Schaid, Preston Stafford

Shock· December 2022

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Postinjury complement C4 activation is associated with adverse outcomes and is potentially influenced by plasma resuscitation.
Terry R Schaid, Kirk C Hansen, Angela Sauaia, Ernest E Moore, Margot DeBot

J Trauma Acute Care Surg· November 2022

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A combat casualty relevant dismounted complex blast injury model in swine.
Alexis L Cralley, Ernest E Moore, Daniel Kissau, Julia R Coleman, Navin Vigneshwar, Margot DeBot

J Trauma Acute Care Surg· August 2022

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Zone 1 REBOA in a combat DCBI swine model does not worsen brain injury.
Alexis L Cralley, Ernest E Moore, Charles J Fox, Daniel Kissau, Margot DeBot

Surgery· August 2022

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Trauma-induced hypocalcemia.
Margot DeBot, Angela Sauaia, Terry Schaid, Ernest E Moore

Transfusion· August 2022

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Astrocytes and pericytes attenuate severely injured patient plasma mediated expression of tight junction proteins in endothelial cells.
Preston Stafford, Sanchayita Mitra, Margot Debot, Patrick Lutz, Arthur Stem

PLoS One· July 2022

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The Influence of Full-Thickness Chondral Defects on Outcomes Following Meniscal Allograft Transplantation: A Comparative Study.
Bryan M Saltzman, Maximilian A Meyer, Timothy S Leroux, Matthew E Gilelis, Margot Debot

Arthroscopy· February 2018

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Rhesus macaque and mouse models for down-selecting circumsporozoite protein based malaria vaccines differ significantly in immunogenicity and functional outcomes.
Timothy W Phares, Anthony D May, Christopher J Genito, Nathan A Hoyt, Farhat A Khan, Margot DeBot

Malar J· March 2017

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Head-to-Head Comparison of Soluble vs. Qβ VLP Circumsporozoite Protein Vaccines Reveals Selective Enhancement of NANP Repeat Responses.
Farhat Khan, Mike Porter, Robert Schwenk, Margot DeBot, Philippe Saudan

PLoS One· June 2016

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IgG2 antibodies against a clinical grade Plasmodium falciparum CSP vaccine antigen associate with protection against transgenic sporozoite challenge in mice.
Robert Schwenk, Margot DeBot, Michael Porter, Jennifer Nikki, Lisa Rein

PLoS One· December 2015

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Transgenic parasites stably expressing full-length Plasmodium falciparum circumsporozoite protein as a model for vaccine down-selection in mice using sterile protection as an endpoint.
Michael D Porter, Jennifer Nicki, Christopher D Pool, Margot DeBot, Ratish M Illam

Clin Vaccine Immunol· June 2013

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