Publications by authors named "Maria A Halili"

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E
Expression, purification and characterization of the suppressor of copper sensitivity (Scs) B membrane protein from Proteus mirabilis.
Russell J Jarrott, Emily J Furlong, Guillaume A Petit, David Drew, Jennifer L Martin, Maria A Halili

Protein Expr Purif· May 2022

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The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity.
Guillaume A Petit, Yaoqin Hong, Karrera Y Djoko, Andrew E Whitten, Emily J Furlong, Maria A Halili

Acta Crystallogr D Struct Biol· March 2022

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Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA.
Guillaume A Petit, Biswaranjan Mohanty, Róisín M McMahon, Stefan Nebl, David H Hilko, Maria A Halili

Acta Crystallogr D Struct Biol· January 2022

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The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening.
Sarah L Mueller, Panagiotis K Chrysanthopoulos, Maria A Halili, Caryn Hepburn, Tom Nebl

Molecules· May 2021

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Prediction of Burkholderia pseudomallei DsbA substrates identifies potential virulence factors and vaccine targets.
Ben Vezina, Guillaume A Petit, Jennifer L Martin, Maria A Halili

PLoS One· December 2020

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NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide-dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei.
Stefan Nebl, Wesam S Alwan, Martin L Williams, Gaurav Sharma, Ashley Taylor, Maria A Halili

J Biomol NMR· November 2020

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Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development.
Signe Christensen, Maria A Halili, Natalie Strange, Guillaume A Petit, Wilhelmina M Huston

PLoS One· March 2020

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Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity.
Jessica A Rowley, Robert C Reid, Eunice K Y Poon, Kai-Chen Wu, Junxian Lim, Maria A Halili

J Med Chem· January 2020

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Author Correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.
Emily J Furlong, Alvin W Lo, Fabian Kurth, Lakshmanane Premkumar, Makrina Totsika, Maria A Halili

Nat Commun· March 2019

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The atypical thiol-disulfide exchange protein α-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase.
Patricia M Walden, Andrew E Whitten, Lakshmanane Premkumar, Maria A Halili, Begoña Heras

Acta Crystallogr D Struct Biol· March 2019

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Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a.
Rink-Jan Lohman, Johan K Hamidon, Robert C Reid, Jessica A Rowley, Mei-Kwan Yau, Maria A Halili

Nat Commun· August 2017

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A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.
Emily J Furlong, Alvin W Lo, Fabian Kurth, Lakshmanane Premkumar, Makrina Totsika, Maria A Halili

Nat Commun· July 2017

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Small molecule inhibitors of disulfide bond formation by the bacterial DsbA-DsbB dual enzyme system.
Maria A Halili, Prabhakar Bachu, Fredrik Lindahl, Chérine Bechara, Biswaranjan Mohanty

ACS Chem Biol· April 2015

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Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence.
Wilko Duprez, Lakshmanane Premkumar, Maria A Halili, Fredrik Lindahl, Robert C Reid

J Med Chem· January 2015

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Comparative sequence, structure and redox analyses of Klebsiella pneumoniae DsbA show that anti-virulence target DsbA enzymes fall into distinct classes.
Fabian Kurth, Kieran Rimmer, Lakshmanane Premkumar, Biswaranjan Mohanty, Wilko Duprez, Maria A Halili

PLoS One· August 2014

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The α-proteobacteria Wolbachia pipientis protein disulfide machinery has a regulatory mechanism absent in γ-proteobacteria.
Patricia M Walden, Maria A Halili, Julia K Archbold, Fredrik Lindahl, David P Fairlie

PLoS One· August 2014

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Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to elongation factor EF-Tu reveals a novel protein interaction site.
Lakshmanane Premkumar, Fabian Kurth, Wilko Duprez, Morten K Grøftehauge, Gordon J King, Maria A Halili

J Biol Chem· July 2014

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The 1.2 Å resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production.
Patricia M Walden, Begoña Heras, Kai-En Chen, Maria A Halili, Kieran Rimmer

Acta Crystallogr D Biol Crystallogr· October 2012

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Histone deacetylases as regulators of inflammation and immunity.
Melanie R Shakespear, Maria A Halili, Katharine M Irvine, David P Fairlie, Matthew J Sweet

Trends Immunol· July 2011

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Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS.
Maria A Halili, Melanie R Andrews, Larisa I Labzin, Kate Schroder, Gabriele Matthias

J Leukoc Biol· June 2010

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Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats.
Abishek Iyer, Andrew Fenning, Junxian Lim, Giang T Le, Robert C Reid, Maria A Halili

Br J Pharmacol· April 2010

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Structure-activity relationships for substrate-based inhibitors of human complement factor B.
Gloria Ruiz-Gómez, Junxian Lim, Maria A Halili, Giang T Le, Praveen K Madala

J Med Chem· October 2009

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Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation.
Maria A Halili, Gloria Ruiz-Gómez, Giang T Le, Giovanni Abbenante, David P Fairlie

Biochemistry· September 2009

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Histone deacetylase inhibitors in inflammatory disease.
Maria A Halili, Melanie R Andrews, Matthew J Sweet, David P Fairlie

Curr Top Med Chem· June 2009

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