Publications by authors named "Maria Askmyr"

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The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies.
Michelle H Nelson, Sara Fritzell, Robert Miller, Doreen Werchau, Danielle Van Citters, Maria Askmyr

Mol Cancer Ther· January 2023

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Gene therapy for infantile malignant osteopetrosis: review of pre-clinical research and proof-of-concept for phenotypic reversal.
Ilana Moscatelli, Elena Almarza, Axel Schambach, David Ricks, Ansgar Schulz, Maria Askmyr

Mol Ther Methods Clin Dev· March 2021

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A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells.
Sofia von Palffy, Niklas Landberg, Carl Sandén, Dimitra Zacharaki, Mansi Shah, Maria Askmyr

Haematologica· August 2020

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CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting.
Niklas Landberg, Sofia von Palffy, Maria Askmyr, Henrik Lilljebjörn, Carl Sandén

Haematologica· March 2018

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Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells.
Maria Askmyr, Sofia von Palffy, Nils Hansen, Niklas Landberg, Carl Högberg

PLoS One· October 2017

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IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models.
Helena Ågerstam, Nils Hansen, Sofia von Palffy, Carl Sandén, Kristian Reckzeh, Maria Askmyr

Blood· December 2016

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Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.
Henrik Lilljebjörn, Rasmus Henningsson, Axel Hyrenius-Wittsten, Linda Olsson, Christina Orsmark-Pietras, Maria Askmyr

Nat Commun· June 2016

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Ciliary neurotrophic factor has intrinsic and extrinsic roles in regulating B cell differentiation and bone structure.
Maria Askmyr, Kirby E White, Tanja Jovic, Hannah A King, Julie M Quach

Sci Rep· October 2015

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Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
Helena Ågerstam, Christine Karlsson, Nils Hansen, Carl Sandén, Maria Askmyr

Proc Natl Acad Sci U S A· August 2015

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Myelosuppressive therapies significantly increase pro-inflammatory cytokines and directly cause bone loss.
Julie M Quach, Maria Askmyr, Tanja Jovic, Emma K Baker, Nicole C Walsh

J Bone Miner Res· May 2015

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Lentiviral gene transfer of TCIRG1 into peripheral blood CD34(+) cells restores osteoclast function in infantile malignant osteopetrosis.
Ilana Moscatelli, Christian Schneider Thudium, Carmen Flores, Ansgar Schulz, Maria Askmyr

Bone· November 2013

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Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.
Maria Askmyr, Helena Ågerstam, Nils Hansen, Sandra Gordon, Alexandros Arvanitakis

Blood· May 2013

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Dissociation of bone resorption and bone formation in adult mice with a non-functional V-ATPase in osteoclasts leads to increased bone strength.
Kim Henriksen, Carmen Flores, Jesper S Thomsen, Anne-Marie Brüel, Christian S Thudium, Maria Askmyr

PLoS One· May 2012

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Defining the hematopoietic stem cell niche: the chicken and the egg conundrum.
Sofie Singbrant, Maria Askmyr, Louise E Purton, Carl R Walkley

J Cell Biochem· June 2011

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Effects of the bone marrow microenvironment on hematopoietic malignancy.
Maria Askmyr, Julie Quach, Louise E Purton

Bone· January 2011

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Nonablative neonatal bone marrow transplantation rapidly reverses severe murine osteopetrosis despite low-level engraftment and lack of selective expansion of the osteoclastic lineage.
Carmen Flores, Teun J de Vries, Ilana Moscatelli, Maria Askmyr, Ton Schoenmaker

J Bone Miner Res· September 2010

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What is the true nature of the osteoblastic hematopoietic stem cell niche?
Maria Askmyr, Natalie A Sims, T John Martin, Louise E Purton

Trends Endocrinol Metab· August 2009

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Prospects for gene therapy of osteopetrosis.
Maria Askmyr, Carmen Flores, Anders Fasth, Johan Richter

Curr Gene Ther· June 2009

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Low-dose busulphan conditioning and neonatal stem cell transplantation preserves vision and restores hematopoiesis in severe murine osteopetrosis.
Maria Askmyr, Johan Holmberg, Carmen Flores, Mats Ehinger, Tord Hjalt

Exp Hematol· February 2009

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Towards a better understanding and new therapeutics of osteopetrosis.
Maria K Askmyr, Anders Fasth, Johan Richter

Br J Haematol· March 2008

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