Publications by authors named "Maria B Bagh"

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Niemann Pick C1 mistargeting disrupts lysosomal cholesterol homeostasis contributing to neurodegeneration in a Batten disease model.
Abhilash P Appu, Maria B Bagh, Nisha Plavelil, Avisek Mondal, Tamal Sadhukhan

Sci Adv· May 2025

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Disruption of lysosomal nutrient sensing scaffold contributes to pathogenesis of a fatal neurodegenerative lysosomal storage disease.
Maria B Bagh, Abhilash P Appu, Tamal Sadhukhan, Avisek Mondal, Nisha Plavelil

J Biol Chem· February 2024

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Ppt1-deficiency dysregulates lysosomal Ca homeostasis contributing to pathogenesis in a mouse model of CLN1 disease.
Avisek Mondal, Abhilash P Appu, Tamal Sadhukhan, Maria B Bagh, Rafael M Previde

J Inherit Metab Dis· May 2022

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Ablation of microRNA-155 and neuroinflammation in a mouse model of CLN1-disease.
Tamal Sadhukhan, Maria B Bagh, Sriparna Sadhukhan, Abhilash P Appu, Avisek Mondal

Biochem Biophys Res Commun· September 2021

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In a mouse model of INCL reduced S-palmitoylation of cytosolic thioesterase APT1 contributes to microglia proliferation and neuroinflammation.
Tamal Sadhukhan, Maria B Bagh, Abhilash P Appu, Avisek Mondal, Wei Zhang

J Inherit Metab Dis· July 2021

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Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis.
Chinmoy Sarkar, Tamal Sadhukhan, Maria B Bagh, Abhilash P Appu, Goutam Chandra

J Inherit Metab Dis· September 2020

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Cln3-mutations underlying juvenile neuronal ceroid lipofuscinosis cause significantly reduced levels of Palmitoyl-protein thioesterases-1 (Ppt1)-protein and Ppt1-enzyme activity in the lysosome.
Abhilash P Appu, Maria B Bagh, Tamal Sadhukhan, Avisek Mondal, Sydney Casey

J Inherit Metab Dis· September 2019

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Emerging new roles of the lysosome and neuronal ceroid lipofuscinoses.
Anil B Mukherjee, Abhilash P Appu, Tamal Sadhukhan, Sydney Casey, Avisek Mondal, Maria B Bagh

Mol Neurodegener· January 2019

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Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model.
Maria B Bagh, Shiyong Peng, Goutam Chandra, Zhongjian Zhang, Satya P Singh

Nat Commun· March 2017

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Suppression of agrin-22 production and synaptic dysfunction in Cln1 (-/-) mice.
Shiyong Peng, Jianhua Xu, Kenneth A Pelkey, Goutam Chandra, Zhongjian Zhang, Maria B Bagh

Ann Clin Transl Neurol· December 2015

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Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders.
Goutam Chandra, Maria B Bagh, Shiyong Peng, Arjun Saha, Chinmoy Sarkar

Hum Mol Genet· October 2015

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Combination of N-acetylcysteine, α-lipoic acid and α-tocopherol substantially prevents the brain synaptosomal alterations and memory and learning deficits of aged rats.
Ishita Guha Thakurta, Priyanjalee Banerjee, Maria Bindu Bagh, Arindam Ghosh, Arghyadip Sahoo

Exp Gerontol· February 2014

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Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43.
Eryan Kong, Shiyong Peng, Goutam Chandra, Chinmoy Sarkar, Zhongjian Zhang, Maria B Bagh

J Biol Chem· March 2013

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Mitochondrial Dysfunction during Brain Aging: Role of Oxidative Stress and Modulation by Antioxidant Supplementation.
Sasanka Chakrabarti, Soumyabrata Munshi, Kalpita Banerjee, Ishita Guha Thakurta, Maitrayee Sinha, Maria Bindu Bagh

Aging Dis· June 2011

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Age-related oxidative decline of mitochondrial functions in rat brain is prevented by long term oral antioxidant supplementation.
Maria Bindu Bagh, Ishita Guha Thakurta, Mallika Biswas, Prajna Behera, Sasanka Chakrabarti

Biogerontology· April 2011

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Dietary supplementation with N-acetylcysteine, alpha-tocopherol and alpha-lipoic acid prevents age related decline in Na(+),K (+)-ATPase activity and associated peroxidative damage in rat brain synaptosomes.
Maria Bindu Bagh, Arpan Kumar Maiti, Arun Roy, Sasanka Chakrabarti

Biogerontology· December 2008

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Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in rat brain: implications in the neuroprotective therapy of Parkinson's disease.
Maria B Bagh, Arpan K Maiti, Sirsendu Jana, Kalpita Banerjee, Arun Roy

Free Radic Res· June 2008

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Dopamine but not 3,4-dihydroxy phenylacetic acid (DOPAC) inhibits brain respiratory chain activity by autoxidation and mitochondria catalyzed oxidation to quinone products: implications in Parkinson's disease.
Sirsendu Jana, Arpan Kumar Maiti, Maria Bindu Bagh, Kalpita Banerjee, Amitabha Das

Brain Res· March 2007

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