Publications by authors named "Maria B Cassera"

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Characterization of β-Carboline Derivatives Reveals a High Barrier to Resistance and Potent Activity against Ring-Stage and DHA-Induced Dormant .
Reagan S Haney, Joshua H Butler, Lyric A Wardlaw, Emilio F Merino, Victoria Mendiola, Maria Belen Cassera

ACS Infect Dis· November 2025

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Benzo-ring modification on Malaria Box hit MMV008138: effects on antimalarial potency and microsomal stability.
Maryam Ghavami, Haibo Li, Lixuan Liu, Joshua H Butler, Sha Ding, Maria B Cassera

RSC Med Chem· October 2025

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Antimalarial spirooxindole alkaloids with a rare 6/5/5/6/6 polycyclic skeleton from the fungus Penicillium citrinum YSC-1 isolated from a medicinal plant.
Pei-Qian Wu, Jun-Su Zhou, Leticia S Do Amaral, Maria B Cassera, Jian-Min Yue

Bioorg Chem· September 2025

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Anti-Malarial Activity of Amentoflavone Isolated from Leaf of Calophyllum Tomentosum Wight.
Ajoy K Bauri, Joshua H Butler, Maria B Cassera, Sabine Foro

Chem Biodivers· February 2025

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Stereospecific Resistance to N2-Acyl Tetrahydro-β-carboline Antimalarials Is Mediated by a PfMDR1 Mutation That Confers Collateral Drug Sensitivity.
Emily K Bremers, Joshua H Butler, Leticia S Do Amaral, Emilio F Merino, Hanan Almolhim, Maria Belen Cassera

ACS Infect Dis· February 2025

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Spirocyclic iridoid alkaloids from .
Xin-Hua Gao, Bin Zhou, Flavia M Zimbres, Zai-Yong Zhang, Maria B Cassera

Org Biomol Chem· January 2025

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β-Carboline-3-carboxamide Antimalarials: Structure-Activity Relationship, ADME-Tox Studies, and Resistance Profiling.
Jopaul Mathew, Bo Zhou, Reagan S Haney, Kevin A Kunz, Leticia S Do Amaral, Maria Belen Cassera

ACS Infect Dis· November 2024

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Aptamer-Based Imaging of Polyisoprenoids in the Malaria Parasite.
Flavia M Zimbres, Emilio F Merino, Grant J Butschek, Joshua H Butler, Frédéric Ducongé, Maria B Cassera

Molecules· December 2023

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Cripowellins Pause Intraerythrocytic Development at the Ring Stage.
Joshua H Butler, Heather J Painter, Emily K Bremers, Priscilla Krai, Manuel Llinás, Maria B Cassera

Molecules· March 2023

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In Vitro Diagnostic Assay to Detect SARS-CoV-2-Neutralizing Antibody in Patient Sera Using Engineered ACE-2 Mini-Protein.
Bruna Andersen Pereira de Jesus, Anderson Albino Gomes, Alex E Clark, Tayse Andrade Rodrigues, Melissa Ledgerwood-Lee, Maria B Cassera

Viruses· December 2022

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Cephalotane-type C diterpenoids from var. .
Zhan-Peng Ge, Bin Zhou, Flavia M Zimbres, Reagan S Haney, Qun-Fang Liu, Maria B Cassera

Org Biomol Chem· November 2022

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Alkyne modified purines for assessment of activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp.
Alona Botnar, Grant Lawrence, Steven P Maher, Amélie Vantaux, Benoît Witkowski, Maria B Cassera

Int J Parasitol· October 2022

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Correction to: Antimalarial Natural Products.
David G I Kingston, Maria Belen Cassera

Prog Chem Org Nat Prod· June 2022

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Enantiopure Benzofuran-2-carboxamides of 1-Aryltetrahydro-β-carbolines Are Potent Antimalarials .
Hanan Almolhim, Sha Ding, Joshua H Butler, Emily K Bremers, Grant J Butschek, Maria B Cassera

ACS Med Chem Lett· March 2022

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Malaria Box-Inspired Discovery of -Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials.
Jopaul Mathew, Sha Ding, Kevin A Kunz, Emily E Stacy, Joshua H Butler, Maria B Cassera

ACS Med Chem Lett· March 2022

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Antimalarial Natural Products.
David G I Kingston, Maria Belen Cassera

Prog Chem Org Nat Prod· January 2022

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Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency.
Seok-Ho Yu, Tong Wang, Kali Wiggins, Raymond J Louie, Emilio F Merino, Maria B Cassera

Genet Med· July 2021

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Flavanones from the Twigs and Barks of Artocarpus lakoocha Having Antiplasmodial and Anti-TB Activities.
Sirada Boonyaketgoson, Yongle Du, Ana L Valenciano Murillo, Maria B Cassera, David G I Kingston

Chem Pharm Bull (Tokyo)· February 2021

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Probing the B- & C-rings of the antimalarial tetrahydro-β-carboline MMV008138 for steric and conformational constraints.
Sha Ding, Maryam Ghavami, Joshua H Butler, Emilio F Merino, Carla Slebodnick, Maria B Cassera

Bioorg Med Chem Lett· November 2020

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Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Esterase.
Joshua H Butler, Rodrigo P Baptista, Ana L Valenciano, Bin Zhou, Jessica C Kissinger, Maria B Cassera

ACS Infect Dis· November 2020

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Metabolomics profiling reveals new aspects of dolichol biosynthesis in Plasmodium falciparum.
Flavia M Zimbres, Ana Lisa Valenciano, Emilio F Merino, Anat Florentin, Nicole R Holderman, Maria Belen Cassera

Sci Rep· August 2020

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Antimalarial diterpenoids from Vitex rotundifolia: Isolation, structure elucidation, and in vitro antiplasmodial activity.
You Ah Kim, Abdul Latif, Chang-Suk Kong, Youngwan Seo, Seema R Dalal, Maria B Cassera

Bioorg Chem· July 2020

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Limonoids from .
Jin-Hai Yu, Hua Zhang, Bin Zhou, Flavia M Zimbres, Seema Dalal, Maria B Cassera

J Nat Prod· June 2020

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Galtonosides A-E: Antiproliferative and Antiplasmodial Cholestane Glycosides from .
Yongle Du, Brooke A Martin, Ana Lisa Valenciano, Jason A Clement, Michael Goetz, Maria B Cassera

J Nat Prod· April 2020

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Anibamine and Its Analogues: Potent Antiplasmodial Agents from .
Yongle Du, Ana Lisa Valenciano, Yumin Dai, Yi Zheng, Feng Zhang, Maria B Cassera

J Nat Prod· March 2020

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