Publications by authors named "Maria C Denis"

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Altered behaviour and immune response in mice with NHLRC2 p.Asp148Tyr variant.
Anniina E Hiltunen, Salla M Kangas, Aishwarya Gondane, Henna Koivisto, Kari Salokas, Maria C Denis

Brain Behav Immun Health· July 2025

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drive synovial hyperplasia and arthritis by targeting cell cycle inhibitors and chromatin remodeling components.
Fani Roumelioti, Christos Tzaferis, Dimitris Konstantopoulos, Dimitra Papadopoulou, Alejandro Prados, Maria C Denis

Elife· September 2024

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A Novel Human Interleukin-23A Overexpressing Mouse Model of Systemic Lupus Erythematosus.
Eleni Christodoulou-Vafeiadou, Christina Geka, Lida Iliopoulou, Lydia Ntari, Maria C Denis

Arthritis Rheumatol· July 2024

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Discovery of the First-in-Class Inhibitors of Hypoxia Up-Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation.
Dimitra Papadopoulou, Vasiliki Mavrikaki, Filippos Charalampous, Christos Tzaferis, Martina Samiotaki, Maria C Denis

Angew Chem Int Ed Engl· April 2024

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Targeting senescence and inflammation in chronic destructive TNF-driven joint pathology.
Nikolaos I Vlachogiannis, Konstantinos Evangelou, Lydia Ntari, Christoforos Nikolaou, Maria C Denis

Mech Ageing Dev· September 2023

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Α Humanized RANKL Transgenic Mouse Model of Progestin-Induced Mammary Carcinogenesis for Evaluation of Novel Therapeutics.
Anthi Kolokotroni, Evi Gkikopoulou, Vagelis Rinotas, Lydia Ntari, Danae Zareifi, Maria C Denis

Cancers (Basel)· August 2023

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Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis.
Dimitra Papadopoulou, Fani Roumelioti, Christos Tzaferis, Panagiotis Chouvardas, Anna-Kathrine Pedersen, Maria C Denis

JCI Insight· May 2023

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TNF overexpression and dexamethasone treatment impair chondrogenesis and bone growth in an additive manner.
Yunhan Zhao, Bettina Celvin, Maria C Denis, Niki Karagianni, Cecilia Aulin

Sci Rep· October 2022

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Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice.
Irini Papazian, Eleni Tsoukala, Athena Boutou, Maria Karamita, Konstantinos Kambas, Maria C Denis

J Neuroinflammation· September 2021

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'SMASH' recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models.
Silvia Hayer, Margriet J Vervoordeldonk, Maria C Denis, Marietta Armaka, Markus Hoffmann

Ann Rheum Dis· June 2021

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Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment.
Lydia Ntari, Christoforos Nikolaou, Ksanthi Kranidioti, Dimitra Papadopoulou, Eleni Christodoulou-Vafeiadou, Maria C Denis

J Transl Med· April 2021

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Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis.
Eleni Christodoulou-Vafeiadou, Christina Geka, Lydia Ntari, Ksanthi Kranidioti, Eleni Argyropoulou, Maria C Denis

Arthritis Res Ther· October 2020

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An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthritis.
Niki Karagianni, Ksanthi Kranidioti, Nikolaos Fikas, Maria Tsochatzidou, Panagiotis Chouvardas, Maria C Denis

PLoS Comput Biol· May 2019

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Comorbid TNF-mediated heart valve disease and chronic polyarthritis share common mesenchymal cell-mediated aetiopathogenesis.
Lydia Ntari, Maria Sakkou, Panagiotis Chouvardas, Iordanis Mourouzis, Alejandro Prados, Maria C Denis

Ann Rheum Dis· June 2018

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Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis.
Maria Sakkou, Panagiotis Chouvardas, Lydia Ntari, Alejandro Prados, Kristin Moreth, Maria C Denis

JCI Insight· April 2018

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Improved topical delivery of tacrolimus: A novel composite hydrogel formulation for the treatment of psoriasis.
Doris Gabriel, Thibault Mugnier, Herve Courthion, Ksanthi Kranidioti, Niki Karagianni, Maria C Denis

J Control Release· November 2016

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Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess treatments targeting human TNFα in rheumatoid arthritis.
Adrian Richard Moore, Sarah Allden, Tim Bourne, Maria C Denis, Ksanthi Kranidioti

J Transl Med· October 2014

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Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model.
Ioannis Pandis, Caroline Ospelt, Niki Karagianni, Maria C Denis, Martin Reczko

Ann Rheum Dis· October 2012

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TNFR2 on non-haematopoietic cells is required for Foxp3+ Treg-cell function and disease suppression in EAE.
Niki Tsakiri, Dimitrios Papadopoulos, Maria C Denis, Dimos-Dimitrios Mitsikostas, George Kollias

Eur J Immunol· February 2012

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Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes.
Stuart E Turvey, Eric Swart, Maria C Denis, Umar Mahmood, Christophe Benoist

J Clin Invest· September 2005

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Imaging inflammation of the pancreatic islets in type 1 diabetes.
Maria C Denis, Umar Mahmood, Christophe Benoist, Diane Mathis, Ralph Weissleder

Proc Natl Acad Sci U S A· August 2004

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Native and recombinant interleukin-2, two functionally distinct molecules.
Maria C Denis, Brigitte T Huber

Mol Immunol· September 2003

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