Publications by authors named "Maria C Florian"

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Deep learning predicts haematopoietic stem cell ageing from 3D chromatin images.
Pablo Iáñez Picazo, Eva Mejía-Ramírez, Dario Di Bari, Elena Vitali, Maria Carolina Florian

bioRxiv· December 2025

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A Notch trans-activation to cis-inhibition switch underlies hematopoietic stem cell aging.
Francesca Matteini, Roshana Thambyrajah, Sara Montserrat-Vazquez, Sascha Jung, Alba Ferrer-Perez, Maria Carolina Florian

Blood· October 2025

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Haematopoietic ageing in health and lifespan.
Rebecca Andersson, Eva Mejia-Ramirez, Maria Carolina Florian

Nat Cell Biol· September 2025

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Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate.
Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Maria Carolina Florian

Nat Commun· February 2024

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Fast and high-fidelity 3D imaging protocol for stem cells and niche components for mouse organs and tissues.
Mehmet Saçma, Francesca Matteini, Medhanie A Mulaw, Ali Hageb, Ruzhica Bogeska, Maria Carolina Florian

STAR Protoc· September 2022

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Living a longer life: unique lessons from the naked mole-rat blood system.
Rebecca Andersson, Maria Carolina Florian

EMBO J· August 2022

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Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Ruzhica Bogeska, Ana-Matea Mikecin, Paul Kaschutnig, Malak Fawaz, Marleen Büchler-Schäff, Florian Buettner, Maria Carolina Florian

Cell Stem Cell· August 2022

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Aging of human hematopoietic stem cells is linked to changes in Cdc42 activity.
Amanda Amoah, Anja Keller, Ramiz Emini, Markus Hoenicka, Andreas Liebold, Maria Carolina Florian

Haematologica· February 2022

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Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.
Ravinder Kandi, Katharina Senger, Ani Grigoryan, Karin Soller, Vadim Sakk, Maria Carolina Florian

EMBO Rep· December 2021

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An aged bone marrow niche restrains rejuvenated hematopoietic stem cells.
Novella Guidi, Gina Marka, Vadim Sakk, Yi Zheng, Maria Carolina Florian

Stem Cells· August 2021

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Attrition of X Chromosome Inactivation in Aged Hematopoietic Stem Cells.
Ani Grigoryan, Johannes Pospiech, Stephen Krämer, Daniel Lipka, Thomas Liehr, Maria Carolina Florian

Stem Cell Reports· April 2021

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A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells.
Rajiv L Tiwari, Pratibha Mishra, Nicola Martin, Nikhil Oommen George, Vadim Sakk, Maria Carolina Florian

Aging (Albany NY)· February 2021

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Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice.
Maria Carolina Florian, Hanna Leins, Michael Gobs, Yang Han, Gina Marka

Aging Cell· September 2020

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Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway.
Hassen Kared, Shu Wen Tan, Mai Chan Lau, Marion Chevrier, Crystal Tan, Maria Carolina Florian

Nat Commun· February 2020

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Understanding intrinsic hematopoietic stem cell aging.
Eva Mejia-Ramirez, Maria Carolina Florian

Haematologica· January 2020

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Acute Myeloid Leukemia: Aging and Epigenetics.
Polina Zjablovskaja, Maria Carolina Florian

Cancers (Basel)· December 2019

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Haematopoietic stem cells in perisinusoidal niches are protected from ageing.
Mehmet Saçma, Johannes Pospiech, Ruzhica Bogeska, Walter de Back, Jan-Philipp Mallm, Maria Carolina Florian

Nat Cell Biol· November 2019

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Hematopoietic Stem Cell Dynamics Are Regulated by Progenitor Demand: Lessons from a Quantitative Modeling Approach.
Markus Klose, Maria Carolina Florian, Alexander Gerbaulet, Hartmut Geiger, Ingmar Glauche

Stem Cells· July 2019

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Rational identification of a Cdc42 inhibitor presents a new regimen for long-term hematopoietic stem cell mobilization.
Wei Liu, Wei Du, Xun Shang, Lei Wang, Chris Evelyn, Maria Carolina Florian

Leukemia· March 2019

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LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells.
Ani Grigoryan, Novella Guidi, Katharina Senger, Thomas Liehr, Karin Soller, Maria Carolina Florian

Genome Biol· November 2018

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Septin 6 regulates engraftment and lymphoid differentiation potential of murine long-term hematopoietic stem cells.
Katharina Senger, Gina Marka, Karin Soller, Vadim Sakk, Maria Carolina Florian

Exp Hematol· November 2017

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Expression and Activity of the Small RhoGTPase Cdc42 in Blood Cells of Older Adults Are Associated With Age and Cardiovascular Disease.
Maria Carolina Florian, Jochen Klenk, Gina Marka, Karin Soller, Hady Kiryakos, Florian Herbolsheimer

J Gerontol A Biol Sci Med Sci· September 2017

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Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells.
Novella Guidi, Mehmet Sacma, Ludger Ständker, Karin Soller, Gina Marka, Maria Carolina Florian

EMBO J· May 2017

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Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells.
Novella Guidi, Mehmet Sacma, Ludger Ständker, Karin Soller, Gina Marka, Maria Carolina Florian

EMBO J· April 2017

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Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs.
Bettina M Moehrle, Kalpana Nattamai, Andreas Brown, Maria C Florian, Marnie Ryan

Cell Rep· December 2015

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