Publications by authors named "Maria Cano-Abad"

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The CALHM1 blocker CGP37157 increases seizure severity during status epilepticus in adult mice.
Meghma Mitra, Amaya Sanz Rodriguez, Norman Delanty, Alan Beausang, Francesca M Brett, Maria F Cano-Abad

Purinergic Signal· December 2025

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Cytotoxicity Models in Chromaffin Cells to Evaluate Neuroprotective Compounds.
María F Cano-Abad, Manuela G López

Methods Mol Biol· October 2022

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Intracellular calcium and inflammatory markers, mediated by purinergic stimulation, are differentially regulated in monocytes of patients with major depressive disorder.
Javier Garrosa-Jiménez, Yolanda Sánchez Carro, María C Ovejero-Benito, Eric Del Sastre, Antonio G García, María F Cano-Abad

Neurosci Lett· November 2021

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The purinergic P2X7 receptor as a potential drug target to combat neuroinflammation in neurodegenerative diseases.
Francesco Calzaferri, Cristina Ruiz-Ruiz, Antonio M G de Diego, Ricardo de Pascual, Iago Méndez-López, María F Cano-Abad

Med Res Rev· November 2020

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Molecular and Pharmacological Modulation of CALHM1 Promote Neuroprotection against Oxygen and Glucose Deprivation in a Model of Hippocampal Slices.
Javier Garrosa, Iñigo Paredes, Philippe Marambaud, Manuela G López, María F Cano-Abad

Cells· March 2020

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The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca dysregulation, and mitochondrial abnormalities.
María Dolores Martin-de-Saavedra, Elisa Navarro, Ana J Moreno-Ortega, Mauricio P Cunha, Izaskun Buendia, María F Cano-Abad

J Neurochem· April 2018

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Chromaffin cells as a model to evaluate mechanisms of cell death and neuroprotective compounds.
Cristobal de Los Rios, Maria F Cano-Abad, Mercedes Villarroya, Manuela G López

Pflugers Arch· January 2018

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Neuroprotective Effect of the Novel Compound ITH33/IQM9.21 Against Oxidative Stress and Na(+) and Ca(2+) Overload in Motor Neuron-like NSC-34 Cells.
Ana J Moreno-Ortega, Lamiaa Mouhid Al-Achbili, Elba Alonso, Cristóbal de Los Ríos, Antonio G García, María F Cano-Abad

Neurotox Res· October 2016

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ITH33/IQM9.21 provides neuroprotection in a novel ALS model based on TDP-43 and Na/Ca overload induced by VTD.
Lamia Mouhid Al-Achbili, Ana J Moreno-Ortega, Jorge Matías-Guiu, María F Cano-Abad, Ana Ruiz-Nuño

Neurosci Lett· October 2016

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Neuroprotective profile of pyridothiazepines with blocking activity of the mitochondrial Na(+)/Ca(2+) exchanger.
Francisco J Martínez-Sanz, Rocío Lajarín-Cuesta, Laura González-Lafuente, Ana J Moreno-Ortega, Eva Punzón, María F Cano-Abad

Eur J Med Chem· February 2016

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CALHM1 and its polymorphism P86L differentially control Ca²⁺homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β.
Ana José Moreno-Ortega, Izaskun Buendia, Lamia Mouhid, Javier Egea, Susana Lucea, María F Cano-Abad

Aging Cell· December 2015

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Benzothiazepine CGP37157 Analogues Exert Cytoprotection in Various in Vitro Models of Neurodegeneration.
Francisco J Martínez-Sanz, Rocío Lajarín-Cuesta, Ana J Moreno-Ortega, Laura González-Lafuente, Jose C Fernández-Morales, María F Cano-Abad

ACS Chem Neurosci· September 2015

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Benzothiazepine CGP37157 and its 2'-isopropyl analogue modulate Ca²⁺ entry through CALHM1.
Ana J Moreno-Ortega, Francisco J Martínez-Sanz, Rocío Lajarín-Cuesta, Cristóbal de Los Rios, María F Cano-Abad

Neuropharmacology· August 2015

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Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca(2+) release from the endoplasmic reticulum.
María Guerra-Álvarez, Ana J Moreno-Ortega, Elisa Navarro, José Carlos Fernández-Morales, Javier Egea, María F Cano-Abad

J Neurochem· May 2015

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Nanomolar ouabain elicits apoptosis through a direct action on HeLa cell mitochondria.
Elba Alonso, María F Cano-Abad, Ana J Moreno-Ortega, Jesús Novalbos, Juan Milla

Steroids· November 2013

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Imatinib assay by high-performance liquid chromatography in tandem mass spectrometry with solid-phase extraction in human plasma.
Jose María Moreno, Aneta Wojnicz, Juan Luis Steegman, Maria F Cano-Abad, Ana Ruiz-Nuño

Biomed Chromatogr· April 2013

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Cell-permeable gomesin peptide promotes cell death by intracellular Ca(2+) overload.
Edgar J Paredes-Gamero, Rafael L Casaes-Rodrigues, Gioconda E D D Moura, Tatiana M Domingues, Marcus V Buri, María F Cano-Abad

Mol Pharm· September 2012

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Selectivity of action of pregabalin on Ca(2+) channels but not on fusion pore, exocytotic machinery, or mitochondria in chromaffin cells of the adrenal gland.
Alicia Hernández-Vivanco, Alberto Pérez-Alvarez, José Carlos Caba-González, María Teresa Alonso, Ana José Moreno-Ortega, María Cano-Abad

J Pharmacol Exp Ther· August 2012

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Ouabain enhances exocytosis through the regulation of calcium handling by the endoplasmic reticulum of chromaffin cells.
Juan Milla, Mónica S Montesinos, Jose David Machado, Ricardo Borges, Elba Alonso, María F Cano-Abad

Cell Calcium· October 2011

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Measurement of Ca²+ entry using ⁴⁵Ca²+.
Mercedes Villarroya, Manuela G López, María F Cano-Abad, Antonio G García

Methods Mol Biol· August 2011

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Mitochondria sense with different kinetics the calcium entering into HeLa cells through calcium channels CALHM1 and mutated P86L-CALHM1.
Ana J Moreno-Ortega, Ana Ruiz-Nuño, Antonio G García, María F Cano-Abad

Biochem Biophys Res Commun· January 2010

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Bcl2 mitigates Ca2+ entry and mitochondrial Ca2+ overload through downregulation of L-type Ca2+ channels in PC12 cells.
Natacha Díaz-Prieto, Ivan Herrera-Peco, Antonio Miguel G de Diego, Ana Ruiz-Nuño, Sonia Gallego-Sandín, María F Cano-Abad

Cell Calcium· October 2008

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Pharmacological and biophysical properties of Ca2+ channels and subtype distributions in human adrenal chromaffin cells.
Alberto Pérez-Alvarez, Alicia Hernández-Vivanco, María Cano-Abad, Almudena Albillos

Pflugers Arch· September 2008

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Measurement of Ca2+ entry using 45Ca2+.
Mercedes Villarroya, Manuela G López, María F Cano-Abad, Antonio G García

Methods Mol Biol· February 2006

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Albumin prevents mitochondrial depolarization and apoptosis elicited by endoplasmic reticulum calcium depletion of neuroblastoma cells.
Sonia Gallego-Sandín, Jesús Novalbos, Aránzazu Rosado, María F Cano-Abad, Esperanza Arias

Eur J Pharmacol· September 2005

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