Publications by authors named "Maria E Balasis"

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XPO1 drives resistance to eprenetapopt and azacitidine and can be targeted in TP53-mutated myeloid malignancies.
Traci L Kruer, Ariel Quintana, Hannah Newman, Meghan Ferrall-Fairbanks, Ling Zhang, Maria E Balasis

Blood· October 2025

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RNA Shielding of p65 Is Required to Potentiate Oncogenic Inflammation in TET2-Mutated Clonal Hematopoiesis.
Nana Adjoa Ben-Crentsil, Wazim Mohammed Ismail, Maria E Balasis, Hannah Newman, Ariel Quintana

Cancer Discov· December 2024

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Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML.
Christopher T Letson, Maria E Balasis, Hannah Newman, Moritz Binder, Alexis Vedder

Clin Cancer Res· August 2023

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Progenitor Hierarchy of Chronic Myelomonocytic Leukemia Identifies Inflammatory Monocytic-Biased Trajectory Linked to Worse Outcomes.
Meghan C Ferrall-Fairbanks, Abhishek Dhawan, Brian Johnson, Hannah Newman, Virginia Volpe, Maria E Balasis

Blood Cancer Discov· November 2022

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Integrated Human and Murine Clinical Study Establishes Clinical Efficacy of Ruxolitinib in Chronic Myelomonocytic Leukemia.
Anthony M Hunter, Hannah Newman, Amy E Dezern, David P Steensma, Sandrine Niyongere, Maria E Balasis

Clin Cancer Res· November 2021

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RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis.
Ryan M Carr, Denis Vorobyev, Terra Lasho, David L Marks, Ezequiel J Tolosa, Maria E Balasis

Nat Commun· May 2021

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Phase 1 study of lenzilumab, a recombinant anti-human GM-CSF antibody, for chronic myelomonocytic leukemia.
Mrinal M Patnaik, David A Sallman, Abhishek A Mangaonkar, Rachel Heuer, Jeffery Hirvela, Maria E Balasis

Blood· August 2020

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Effects of on Engraftment of Patient-derived Chronic-Myelomonocytic Leukemia Cells in NSGS Mice.
Alexis R Vedder, Emily L Miedel, Natalie H Ragland, Maria E Balasis, Christopher T Letson

Comp Med· August 2019

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Heterogeneous expression of cytokines accounts for clinical diversity and refines prognostication in CMML.
Sandrine Niyongere, Nolwenn Lucas, Jun-Min Zhou, Samer Sansil, Anthony D Pomicter, Maria E Balasis

Leukemia· January 2019

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Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays.
Catherine C Coombs, Nancy K Gillis, Xianming Tan, Jonathan S Berg, Markus Ball, Maria E Balasis

Clin Cancer Res· December 2018

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Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.
Akihide Yoshimi, Maria E Balasis, Alexis Vedder, Kira Feldman, Yan Ma

Blood· July 2017

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Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study.
Nancy K Gillis, Markus Ball, Qing Zhang, Zhenjun Ma, YuLong Zhao, Maria E Balasis

Lancet Oncol· January 2017

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A Multi-Institution Phase I Trial of Ruxolitinib in Patients with Chronic Myelomonocytic Leukemia (CMML).
Eric Padron, Amy Dezern, Marcio Andrade-Campos, Kris Vaddi, Peggy Scherle, Maria E Balasis

Clin Cancer Res· August 2016

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Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors.
Rongshi Li, Chunwei Cheng, Maria E Balasis, Yan Liu, Thomas P Garner

Eur J Med Chem· January 2015

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Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim.
Chunwei Cheng, Yan Liu, Maria E Balasis, Thomas P Garner, Jerry Li

Mar Drugs· July 2014

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Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim.
Chunwei Cheng, Yan Liu, Maria E Balasis, Nicholas L Simmons, Jerry Li

Mar Drugs· March 2014

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Akt2 and acid ceramidase cooperate to induce cell invasion and resistance to apoptosis.
Norbert Berndt, Ronil Patel, Hua Yang, Maria E Balasis, Saïd M Sebti

Cell Cycle· July 2013

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Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction.
Young B Kim, Maria E Balasis, Kenichiro Doi, Norbert Berndt, Courtney DuBoulay

Bioorg Med Chem Lett· September 2012

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Combination of farnesyltransferase and Akt inhibitors is synergistic in breast cancer cells and causes significant breast tumor regression in ErbB2 transgenic mice.
Maria E Balasis, Kara D Forinash, Y Ann Chen, William J Fulp, Domenico Coppola

Clin Cancer Res· May 2011

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