Publications by authors named "Maria Fazzari"

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GM1 oligosaccharide-mediated rescue in GBA-linked Parkinson's disease via modulation of lysosomal and mitochondrial dysfunctions.
Giulia Lunghi, Carola Pedroli, Ilaria Tagliabue, Dorina Dobi, Maria Grazia Ciampa, Maria Fazzari

Glycoconj J· August 2025

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GM1 Oligosaccharide Modulates Microglial Activation and α-Synuclein Clearance in a Human In Vitro Model.
Giulia Lunghi, Carola Pedroli, Maria Grazia Ciampa, Laura Mauri, Laura Rouvière, Maria Fazzari

Int J Mol Sci· August 2025

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Metabolic and Structural Consequences of GM3 Synthase Deficiency: Insights from an HEK293-T Knockout Model.
Elena Chiricozzi, Giulia Lunghi, Manuela Valsecchi, Emma Veronica Carsana, Rosaria Bassi, Maria Fazzari

Biomedicines· April 2025

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GM1 Oligosaccharide Ameliorates Rett Syndrome Phenotypes In Vitro and In Vivo via Trk Receptor Activation.
Maria Fazzari, Giulia Lunghi, Emma Veronica Carsana, Manuela Valsecchi, Eleonora Spiombi

Int J Mol Sci· October 2024

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GM1 ganglioside exerts protective effects against glutamate-excitotoxicity via its oligosaccharide in wild-type and amyotrophic lateral sclerosis motor neurons.
Giulia Lunghi, Erika Di Biase, Emma Veronica Carsana, Alexandre Henriques, Noelle Callizot, Maria Fazzari

FEBS Open Bio· December 2023

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GM1 structural requirements to mediate neuronal functions.
Maria Fazzari, Giulia Lunghi, Erika Di Biase, Margherita Maggioni, Emma Veronica Carsana

Glycoconj J· December 2023

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GM1 oligosaccharide efficacy against α-synuclein aggregation and toxicity in vitro.
Maria Fazzari, Erika Di Biase, Ludovica Zaccagnini, Alexandre Henriques, Noëlle Callizot

Biochim Biophys Acta Mol Cell Biol Lipids· September 2023

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GM1 Oligosaccharide Efficacy in Parkinson's Disease: Protection against MPTP.
Maria Fazzari, Giulia Lunghi, Alexandre Henriques, Noëlle Callizot, Maria Grazia Ciampa

Biomedicines· April 2023

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Regulation of signal transduction by gangliosides in lipid rafts: focus on GM3-IR and GM1-TrkA interactions.
Giulia Lunghi, Maria Fazzari, Maria Grazia Ciampa, Laura Mauri, Erika Di Biase

FEBS Lett· December 2022

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Novel insights on GM1 and Parkinson's disease: A critical review.
Maria Fazzari, Erika Di Biase, Giulia Lunghi, Laura Mauri, Elena Chiricozzi

Glycoconj J· February 2022

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Gangliosides and the Treatment of Neurodegenerative Diseases: A Long Italian Tradition.
Maria Fazzari, Giulia Lunghi, Elena Chiricozzi, Laura Mauri, Sandro Sonnino

Biomedicines· February 2022

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The structure of gangliosides hides a code for determining neuronal functions.
Giulia Lunghi, Maria Fazzari, Erika Di Biase, Laura Mauri, Elena Chiricozzi

FEBS Open Bio· December 2021

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Glycosphingolipids.
Elena Chiricozzi, Massimo Aureli, Laura Mauri, Erika Di Biase, Giulia Lunghi, Maria Fazzari

Adv Exp Med Biol· September 2021

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Turning the spotlight on the oligosaccharide chain of GM1 ganglioside.
Elena Chiricozzi, Erika Di Biase, Giulia Lunghi, Maria Fazzari, Nicoletta Loberto

Glycoconj J· February 2021

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Modulation of calcium signaling depends on the oligosaccharide of GM1 in Neuro2a mouse neuroblastoma cells.
Giulia Lunghi, Maria Fazzari, Erika Di Biase, Laura Mauri, Sandro Sonnino

Glycoconj J· December 2020

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Gangliosides in the differentiation process of primary neurons: the specific role of GM1-oligosaccharide.
Erika Di Biase, Giulia Lunghi, Maria Fazzari, Margherita Maggioni, Diego Yuri Pomè

Glycoconj J· June 2020

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The oligosaccharide portion of ganglioside GM1 regulates mitochondrial function in neuroblastoma cells.
Maria Fazzari, Matteo Audano, Giulia Lunghi, Erika Di Biase, Nicoletta Loberto

Glycoconj J· June 2020

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GM1 Oligosaccharide Crosses the Human Blood-Brain Barrier In Vitro by a Paracellular Route.
Erika Di Biase, Giulia Lunghi, Margherita Maggioni, Maria Fazzari, Diego Yuri Pomè

Int J Mol Sci· April 2020

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GM1 Ganglioside Is A Key Factor in Maintaining the Mammalian Neuronal Functions Avoiding Neurodegeneration.
Elena Chiricozzi, Giulia Lunghi, Erika Di Biase, Maria Fazzari, Sandro Sonnino

Int J Mol Sci· January 2020

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Parkinson's disease recovery by GM1 oligosaccharide treatment in the B4galnt1 mouse model.
Elena Chiricozzi, Laura Mauri, Giulia Lunghi, Erika Di Biase, Maria Fazzari

Sci Rep· December 2019

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The Neuroprotective Role of the GM1 Oligosaccharide, IINeu5Ac-Gg, in Neuroblastoma Cells.
Elena Chiricozzi, Margherita Maggioni, Erika di Biase, Giulia Lunghi, Maria Fazzari

Mol Neurobiol· October 2019

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Aminoglycoside drugs induce efficient read-through of nonsense mutations, slightly restoring its kinase activity.
Maria Fazzari, Angelisa Frasca, Francesco Bifari, Nicoletta Landsberger

RNA Biol· October 2019

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Splicing Mutations Impairing CDKL5 Expression and Activity Can be Efficiently Rescued by U1snRNA-Based Therapy.
Dario Balestra, Domenico Giorgio, Matteo Bizzotto, Maria Fazzari, Bruria Ben Zeev

Int J Mol Sci· August 2019

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GM1 promotes TrkA-mediated neuroblastoma cell differentiation by occupying a plasma membrane domain different from TrkA.
Elena Chiricozzi, Erika Di Biase, Margherita Maggioni, Giulia Lunghi, Maria Fazzari

J Neurochem· April 2019

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CDKL5 localizes at the centrosome and midbody and is required for faithful cell division.
Isabella Barbiero, Davide Valente, Chetan Chandola, Fiorenza Magi, Anna Bergo, Maria Fazzari

Sci Rep· July 2017

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