Publications by authors named "Maria G Garone"

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HuD impairs neuromuscular junctions and induces apoptosis in human iPSC and Drosophila ALS models.
Beatrice Silvestri, Michela Mochi, Darilang Mawrie, Valeria de Turris, Alessio Colantoni, Maria Giovanna Garone

Nat Commun· November 2024

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HuD (ELAVL4) gain-of-function impairs neuromuscular junctions and induces apoptosis in in vitro and in vivo models of amyotrophic lateral sclerosis.
Beatrice Silvestri, Michela Mochi, Darilang Mawrie, Valeria de Turris, Alessio Colantoni, Maria Giovanna Garone

bioRxiv· March 2024

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The long noncoding RNA nHOTAIRM1 is necessary for differentiation and activity of iPSC-derived spinal motor neurons.
Paolo Tollis, Erika Vitiello, Francesco Migliaccio, Eleonora D'Ambra, Anna Rocchegiani, Maria Giovanna Garone

Cell Death Dis· November 2023

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Digital color-coded molecular barcoding reveals dysregulation of common FUS and FMRP targets in soma and neurites of ALS mutant motoneurons.
Maria Giovanna Garone, Debora Salerno, Alessandro Rosa

Cell Death Discov· January 2023

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Emerging Roles for the RNA-Binding Protein HuD (ELAVL4) in Nervous System Diseases.
Beatrice Silvestri, Michela Mochi, Maria Giovanna Garone, Alessandro Rosa

Int J Mol Sci· November 2022

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Culture of Human iPSC-Derived Motoneurons in Compartmentalized Microfluidic Devices and Quantitative Assays for Studying Axonal Phenotypes.
Maria Giovanna Garone, Chiara D'Antoni, Alessandro Rosa

Methods Mol Biol· May 2022

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ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity.
Maria Giovanna Garone, Nicol Birsa, Maria Rosito, Federico Salaris, Michela Mochi

Commun Biol· September 2021

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FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.
Nicol Birsa, Agnieszka M Ule, Maria Giovanna Garone, Brian Tsang, Francesca Mattedi

Sci Adv· July 2021

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Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor.
Tatiana Tiago, Barbara Hummel, Federica F Morelli, Valentina Basile, Jonathan Vinet, Maria Giovanna Garone

Cell Death Dis· May 2021

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FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.
Jack Humphrey, Nicol Birsa, Carmelo Milioto, Martha McLaughlin, Agnieszka M Ule, Maria G Garone

Nucleic Acids Res· July 2020

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HOTAIRM1 regulates neuronal differentiation by modulating NEUROGENIN 2 and the downstream neurogenic cascade.
Jessica Rea, Valentina Menci, Paolo Tollis, Tiziana Santini, Alexandros Armaos, Maria Giovanna Garone

Cell Death Dis· July 2020

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Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3'UTR binding.
Maria Giovanna Garone, Vincenzo Alfano, Beatrice Salvatori, Clarissa Braccia, Giovanna Peruzzi

Sci Rep· July 2020

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Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis.
Riccardo De Santis, Vincenzo Alfano, Valeria de Turris, Alessio Colantoni, Laura Santini, Maria Giovanna Garone

Cell Rep· June 2019

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Conversion of Human Induced Pluripotent Stem Cells (iPSCs) into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors.
Maria G Garone, Valeria de Turris, Alessandro Soloperto, Carlo Brighi, Riccardo De Santis

J Vis Exp· May 2019

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Direct conversion of human pluripotent stem cells into cranial motor neurons using a piggyBac vector.
Riccardo De Santis, Maria Giovanna Garone, Francesca Pagani, Valeria de Turris, Silvia Di Angelantonio

Stem Cell Res· May 2018

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