Publications by authors named "Maria Hanl"

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Target Engagement Studies and Kinetic Live-Cell Degradation Assays Enable the Systematic Characterization of Histone Deacetylase 6 Degraders.
Maria Hanl, Felix Feller, Irina Honin, Kathrin Tan, Martina Miranda

ACS Pharmacol Transl Sci· September 2025

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Development and Characterization of the First Selective Class IIb Histone Deacetylase Degraders.
Shiyang Zhai, Irina Honin, Linda Schäker-Hübner, Maria Hanl, Lukas Jacobi

J Med Chem· July 2025

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Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a Pan-Degrader.
Felix Feller, Heiko Weber, Martina Miranda, Irina Honin, Maria Hanl

ChemMedChem· May 2025

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Light-activatable photochemically targeting chimeras (PHOTACs) enable the optical control of targeted protein degradation of HDAC6.
Silas L Wurnig, Maria Hanl, Thomas M Geiger, Shiyang Zhai, Ina Dressel

RSC Med Chem· March 2025

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Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties.
Daniel Stopper, Lukas Biermann, Paris R Watson, Jingyu Li, Beate König, Maria Hanl

J Med Chem· February 2025

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Development of the First-in-Class FEM1B-Recruiting Histone Deacetylase Degraders.
Felix Feller, Irina Honin, Martina Miranda, Heiko Weber, Svenja Henze, Maria Hanl

J Med Chem· January 2025

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Hydrazide-Based Class I Selective HDAC Inhibitors Completely Reverse Chemoresistance Synergistically in Platinum-Resistant Solid Cancer Cells.
Fabian B Kraft, Lukas Biermann, Linda Schäker-Hübner, Maria Hanl, Alexandra Hamacher

J Med Chem· October 2024

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Photocaged Histone Deacetylase Inhibitors as Prodrugs in Targeted Cancer Therapy.
Fabian B Kraft, Maria Hanl, Felix Feller, Linda Schäker-Hübner, Finn K Hansen

Pharmaceuticals (Basel)· February 2023

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Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors.
Luisa M Bachmann, Maria Hanl, Felix Feller, Laura Sinatra, Andrea Schöler

Molecules· January 2023

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Borinostats: solid-phase synthesis of carborane-capped histone deacetylase inhibitors with a tailor-made selectivity profile.
Christoph Selg, Andrea Schöler, Julian Schliehe-Diecks, Maria Hanl, Laura Sinatra

Chem Sci· September 2021

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