Publications by authors named "Maria L Giuffrida"

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Unveiling the Potential of a New β-Cyclodextrin-Suxibuzone Conjugate in Proteasome Regulation.
Noemi Bognanni, Stefania Zimbone, Maria Laura Giuffrida, Giuseppe Di Natale, Danilo Milardi

ChemMedChem· November 2025

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SUMO-2 activity is inhibited by non-covalent interactions with the Aβ peptide: an exploration of potential pathogenic mechanisms in Alzheimer's disease.
Valeria Ciaffaglione, Giulia Grasso, Valeria Lanza, Michele Francesco Maria Sciacca, Stefania Zimbone, Maria Laura Giuffrida

Int J Biol Macromol· September 2025

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Human and Mouse Alzheimer's Seeds Differentially Affect Amyloid Deposition and Microglia-Dependent Plaque Response in Aged Mice.
Juana Andreo-Lopez, Cristina Nuñez-Diaz, Kelly Do Huynh, Marie Minh Thu Nguyen, Celia Da Cunha, Maria Laura Giuffrida

Aging Cell· August 2025

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VDAC1-Targeted NHK1 Peptide Recovers Mitochondrial Dysfunction Counteracting Amyloid-β Oligomers Toxicity in Alzheimer's Disease.
Fabrizio Cavallaro, Stefano Conti Nibali, Salvatore Antonio Maria Cubisino, Pietro Caruso, Stefania Zimbone, Maria Laura Giuffrida

Aging Cell· July 2025

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Memantine and amantadine KLVFF peptide conjugates: Synthesis, structure determination, amyloid-β interaction and effects on recognition memory in mice.
Eleonora Bocchieri, Stefania Zimbone, Maria Laura Giuffrida, Giuseppe Di Natale, Giuseppina Sabatino

Eur J Pharmacol· March 2025

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Red-Light-Photosensitized Tyrosine 10 Nitration of β-Amyloid Diverts the Protein from Forming Toxic Aggregates.
Sarah Basile, Cristina Parisi, Francesco Bellia, Stefania Zimbone, Giuseppe Arrabito, Maria Laura Giuffrida

ACS Chem Neurosci· August 2024

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Exploring the therapeutic potential of Aloin: unraveling neuroprotective and anticancer mechanisms, and strategies for enhanced stability and delivery.
Stefania Zimbone, Valeria Romanucci, Armando Zarrelli, Maria Laura Giuffrida, Michele F M Sciacca

Sci Rep· July 2024

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Exploring the Role of Hsp60 in Alzheimer's Disease and Type 2 Diabetes: Suggestion for Common Drug Targeting.
Stefania Zimbone, Maria Carmela Di Rosa, Santina Chiechio, Maria Laura Giuffrida

Int J Mol Sci· August 2023

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Molecular Connections between DNA Replication and Cell Death in β-Amyloid-Treated Neurons.
Filippo Caraci, Annamaria Fidilio, Rosa Santangelo, Giuseppe Caruso, Maria Laura Giuffrida

Curr Neuropharmacol· July 2023

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Amyloid β and Alzheimer's Disease: Molecular Updates from Physiology to Pathology.
Maria Laura Giuffrida

Int J Mol Sci· April 2023

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Aβ Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer's Disease Treatment.
Stefania Zimbone, Maria Laura Giuffrida, Giuseppina Sabatino, Giuseppe Di Natale, Rita Tosto

ACS Chem Neurosci· March 2023

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Green Light-Triggerable Chemo-Photothermal Activity of Cytarabine-Loaded Polymer Carbon Dots: Mechanism and Preliminary In Vitro Evaluation.
Grazia M L Consoli, Maria Laura Giuffrida, Stefania Zimbone, Loredana Ferreri, Ludovica Maugeri

ACS Appl Mater Interfaces· February 2023

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Female Sex Affects Respiratory Function and Exercise Ability in Patients Recovered from COVID-19 Pneumonia.
Lucia Spicuzza, Raffaele Campisi, Stefano Alia, Simone Prestifilippo, Maria Luisa Giuffrida

J Womens Health (Larchmt)· January 2023

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KLVFF oligopeptide-decorated amphiphilic cyclodextrin nanomagnets for selective amyloid beta recognition and fishing.
Antonino Mazzaglia, Giuseppe Di Natale, Rita Tosto, Angela Scala, Giuseppe Sortino, Maria Laura Giuffrida

J Colloid Interface Sci· May 2022

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A novel facile one-pot synthesis of photothermally responsive carbon polymer dots as promising drug nanocarriers.
Grazia Maria Letizia Consoli, Maria Laura Giuffrida, Cristina Satriano, Teresa Musumeci, Giuseppe Forte

Chem Commun (Camb)· March 2022

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Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models.
Michele F M Sciacca, Irina Naletova, Maria Laura Giuffrida, Francesco Attanasio

ACS Chem Neurosci· February 2022

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Investigation on the solid-phase synthesis of silybin prodrugs and their timed-release.
Valeria Romanucci, Maddalena Giordano, Rita Pagano, Stefania Zimbone, Maria Laura Giuffrida

Bioorg Med Chem· November 2021

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β-amyloid monomers drive up neuronal aerobic glycolysis in response to energy stressors.
Rosa Santangelo, Maria Laura Giuffrida, Cristina Satriano, Marianna Flora Tomasello, Stefania Zimbone

Aging (Albany NY)· July 2021

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Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ's Oligomers Cytotoxicity .
Grazia Maria Letizia Consoli, Rita Tosto, Ausilia Baglieri, Salvatore Petralia, Tiziana Campagna, Maria Laura Giuffrida

ACS Chem Neurosci· April 2021

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Trehalose Conjugates of Silybin as Prodrugs for Targeting Toxic Aβ Aggregates.
Sara García-Viñuales, Rashik Ahmed, Michele F M Sciacca, Valeria Lanza, Maria Laura Giuffrida

ACS Chem Neurosci· September 2020

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A promising connection between BDNF and Alzheimer's disease.
Maria Laura Giuffrida, Agata Copani, Enrico Rizzarelli

Aging (Albany NY)· August 2018

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Porphyrin Cyclodextrin Conjugates Modulate Amyloid Beta Peptide Aggregation and Cytotoxicity.
Valentina Oliveri, Stefania Zimbone, Maria Laura Giuffrida, Francesco Bellia, Marianna Flora Tomasello

Chemistry· April 2018

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A New Ratiometric Lysosomal Copper(II) Fluorescent Probe To Map a Dynamic Metallome in Live Cells.
Maria Laura Giuffrida, Giuseppe Trusso Sfrazzetto, Cristina Satriano, Stefania Zimbone, Gaetano A Tomaselli

Inorg Chem· March 2018

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Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type-1 insulin-like growth factor receptors in neuronal cells.
Stefania Zimbone, Irene Monaco, Fiorenza Gianì, Giuseppe Pandini, Agata G Copani, Maria Laura Giuffrida

Aging Cell· February 2018

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Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer's Disease.
Elena Simoni, Roberta Caporaso, Christian Bergamini, Jessica Fiori, Romana Fato, Maria Laura Giuffrida

ACS Med Chem Lett· December 2016

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