Publications by authors named "Maria L Vlaming"

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To Apply Microdosing or Not? Recommendations to Single Out Compounds with Non-Linear Pharmacokinetics.
Sieto Bosgra, Maria L H Vlaming, Wouter H J Vaes

Clin Pharmacokinet· January 2016

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PET-CT imaging with [(18)F]-gefitinib to measure Abcb1a/1b (P-gp) and Abcg2 (Bcrp1) mediated drug-drug interactions at the murine blood-brain barrier.
Maria L H Vlaming, Tilman Läppchen, Harm T Jansen, Suzanne Kivits, Andy van Driel

Nucl Med Biol· November 2015

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Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling.
Sieto Bosgra, Evita van de Steeg, Maria L Vlaming, Kitty C Verhoeckx, Maarten T Huisman

Eur J Pharm Sci· December 2014

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PET imaging of disease progression and treatment effects in the experimental autoimmune encephalomyelitis rat model.
Daniele de Paula Faria, Maria L H Vlaming, Sjef C V M Copray, Frans Tielen, Herma J A Anthonijsz

J Nucl Med· August 2014

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Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.
Maria L H Vlaming, Sebastiaan F Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar

Mol Pharmacol· March 2014

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Automated synthesis of [18F]gefitinib on a modular system.
Tilman Läppchen, Maria L H Vlaming, Erica Custers, Johan Lub, Charles F Sio

Appl Radiat Isot· January 2012

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Impact of abcc2 [multidrug resistance-associated protein (MRP) 2], abcc3 (MRP3), and abcg2 (breast cancer resistance protein) on the oral pharmacokinetics of methotrexate and its main metabolite 7-hydroxymethotrexate.
Maria L H Vlaming, Anita van Esch, Evita van de Steeg, Zeliha Pala, Els Wagenaar

Drug Metab Dispos· August 2011

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Hepatic transport mechanisms of cholyl-L-lysyl-fluorescein.
Dirk R de Waart, Stephanie Häusler, Maria L H Vlaming, Cindy Kunne, Emanuel Hänggi

J Pharmacol Exp Ther· July 2010

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P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide.
Jurjen S Lagas, Lin Fan, Els Wagenaar, Maria L H Vlaming, Olaf van Tellingen

Clin Cancer Res· January 2010

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Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.
Maria L H Vlaming, Anita van Esch, Zeliha Pala, Els Wagenaar, Koen van de Wetering

Mol Cancer Ther· December 2009

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Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.
Dirk R de Waart, Maria L H Vlaming, Cindy Kunne, Alfred H Schinkel, Ronald P J Oude Elferink

Drug Metab Dispos· August 2009

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Pharmacokinetic assessment of multiple ATP-binding cassette transporters: the power of combination knockout mice.
Jurjen S Lagas, Maria L H Vlaming, Alfred H Schinkel

Mol Interv· June 2009

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Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.
Maria L H Vlaming, Zeliha Pala, Anita van Esch, Els Wagenaar, Dirk R de Waart

Clin Cancer Res· May 2009

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Liquid chromatography-tandem mass spectrometric assay for sorafenib and sorafenib-glucuronide in mouse plasma and liver homogenate and identification of the glucuronide metabolite.
Rolf W Sparidans, Maria L H Vlaming, Jurjen S Lagas, Afred H Schinkel, Jan H M Schellens

J Chromatogr B Analyt Technol Biomed Life Sci· January 2009

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Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice.
Maria L H Vlaming, Jurjen S Lagas, Alfred H Schinkel

Adv Drug Deliv Rev· January 2009

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Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.
Maria L H Vlaming, Zeliha Pala, Anita van Esch, Els Wagenaar, Olaf van Tellingen

Clin Cancer Res· December 2008

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Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides.
Koen van de Wetering, Noam Zelcer, Annemieke Kuil, Wouter Feddema, Michel Hillebrand, Maria L H Vlaming

Mol Pharmacol· August 2007

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Breast cancer resistance protein (Bcrp1/Abcg2) is expressed in the harderian gland and mediates transport of conjugated protoporphyrin IX.
Johan W Jonker, Sandra Musters, Maria L H Vlaming, Torsten Plösch, Karin E R Gooijert

Am J Physiol Cell Physiol· June 2007

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Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics.
Jurjen S Lagas, Maria L Vlaming, Olaf van Tellingen, Els Wagenaar, Robert S Jansen

Clin Cancer Res· October 2006

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