Publications by authors named "Maria M Simile"

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HSF1 is a prognostic determinant and therapeutic target in intrahepatic cholangiocarcinoma.
Antonio Cigliano, Isabella Gigante, Marina Serra, Gianpaolo Vidili, Maria M Simile

J Exp Clin Cancer Res· September 2024

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Fatty Acid Synthase Promotes Hepatocellular Carcinoma Growth via S-Phase Kinase-Associated Protein 2/p27 Regulation.
Antonio Cigliano, Maria M Simile, Gianpaolo Vidili, Giovanni M Pes, Maria P Dore

Medicina (Kaunas)· July 2024

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Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma.
Shanshan Deng, Xinjun Lu, Xue Wang, Binyong Liang, Hongwei Xu, Maria Maddalena Simile

Cell Death Dis· June 2024

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Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis.
Sophie Klemm, Katja Evert, Kirsten Utpatel, Alexandra Muggli, Maria M Simile

BMC Cancer· November 2023

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eIF4A1 Is a Prognostic Marker and Actionable Target in Human Hepatocellular Carcinoma.
Sara M Steinmann, Anabel Sánchez-Martín, Elisabeth Tanzer, Antonio Cigliano, Giovanni M Pes, Maria M Simile

Int J Mol Sci· January 2023

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Genetic Predisposition to Hepatocellular Carcinoma.
Rosa M Pascale, Diego F Calvisi, Francesco Feo, Maria M Simile

Metabolites· December 2022

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Nuclear localization dictates hepatocarcinogenesis suppression by glycine N-methyltransferase.
Maria M Simile, Antonio Cigliano, Panagiotis Paliogiannis, Lucia Daino, Roberto Manetti

Transl Oncol· January 2022

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S-Adenosylmethionine: From the Discovery of Its Inhibition of Tumorigenesis to Its Use as a Therapeutic Agent.
Rosa M Pascale, Maria M Simile, Diego F Calvisi, Claudio F Feo, Francesco Feo

Cells· January 2022

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The Warburg Effect 97 Years after Its Discovery.
Rosa Maria Pascale, Diego Francesco Calvisi, Maria Maddalena Simile, Claudio Francesco Feo, Francesco Feo

Cancers (Basel)· September 2020

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Post-translational inhibition of YAP oncogene expression by 4-hydroxynonenal in bladder cancer cells.
Marie Angele Cucci, Alessandra Compagnone, Martina Daga, Margherita Grattarola, Chiara Ullio, Maria Maddalena Simile

Free Radic Biol Med· September 2019

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Experimental Models to Define the Genetic Predisposition to Liver Cancer.
Rosa M Pascale, Maria M Simile, Graziella Peitta, Maria A Seddaiu, Francesco Feo

Cancers (Basel)· September 2019

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Alterations of Methionine Metabolism as Potential Targets for the Prevention and Therapy of Hepatocellular Carcinoma.
Rosa M Pascale, Graziella Peitta, Maria M Simile, Francesco Feo

Medicina (Kaunas)· June 2019

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MicroRNA-203 impacts on the growth, aggressiveness and prognosis of hepatocellular carcinoma by targeting and genes.
Maria M Simile, Graziella Peitta, Maria L Tomasi, Stefania Brozzetti, Claudio F Feo

Oncotarget· April 2019

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Targeted Therapies in Cholangiocarcinoma: Emerging Evidence from Clinical Trials.
Maria Maddalena Simile, Paola Bagella, Gianpaolo Vidili, Angela Spanu, Roberto Manetti

Medicina (Kaunas)· February 2019

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Alterations of methionine metabolism in hepatocarcinogenesis: the emergent role of glycine N-methyltransferase in liver injury.
Maria M Simile, Gavinella Latte, Claudio F Feo, Francesco Feo, Diego F Calvisi

Ann Gastroenterol· July 2018

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Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.
Shanshan Zhang, Xinhua Song, Dan Cao, Zhong Xu, Biao Fan, Maria M Simile

J Hepatol· December 2017

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Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis.
Antonio Cigliano, Maria G Pilo, Lei Li, Gavinella Latte, Marta Szydlowska, Maria M Simile

Oncotarget· October 2017

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Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.
Li Che, Maria G Pilo, Antonio Cigliano, Gavinella Latte, Maria M Simile

Cell Cycle· March 2017

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Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease.
Maria M Simile, Gavinella Latte, Maria I Demartis, Stefania Brozzetti, Diego F Calvisi

Oncotarget· August 2016

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Focal loss of long non-coding RNA-PRAL, as determinant of cell function and phenotype of hepatocellular carcinoma.
Francesco Feo, Maria M Simile, Rosa M Pascale

Ann Transl Med· May 2016

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Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans.
Lei Li, Giulia M Pilo, Xiaolei Li, Antonio Cigliano, Gavinella Latte, Maria M Simile

J Hepatol· February 2016

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Role of transcriptional and posttranscriptional regulation of methionine adenosyltransferases in liver cancer progression.
Maddalena Frau, Maria L Tomasi, Maria M Simile, Maria I Demartis, Fabiana Salis

Hepatology· July 2012

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An expression signature of phenotypic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis.
Maddalena Frau, Maria M Simile, Maria L Tomasi, Maria I Demartis, Lucia Daino

Cell Oncol (Dordr)· June 2012

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Mybl2 expression is under genetic control and contributes to determine a hepatocellular carcinoma susceptible phenotype.
Maddalena Frau, Sara Ladu, Diego F Calvisi, Maria M Simile, Piero Bonelli

J Hepatol· July 2011

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Activation of v-Myb avian myeloblastosis viral oncogene homolog-like2 (MYBL2)-LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of hepatocellular carcinoma with mutant p53.
Diego F Calvisi, Maria M Simile, Sara Ladu, Maddalena Frau, Matthias Evert

Hepatology· April 2011

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