Publications by authors named "Maria Martinez-Iniesta"

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Specific targeting of the pseudogene RPSAP52 reduces ovarian tumor growth in patient-derived orthoxenograft models.
Deepthi Ramesh-Kumar, Anaís Sánchez-Castillo, Marta Soler, Juan Francisco Martin-Tejera, Cristina Oliveira-Mateos, Maria Martinez-Iniesta

Eur J Cancer· November 2025

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Harnessing transcriptional regulation of alternative end-joining to predict cancer treatment.
Roderic Espín, Ferran Medina-Jover, Javier Sigüenza-Andrade, Sònia Farran-Matas, Francesca Mateo

NAR Cancer· March 2025

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RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade.
Marie-Julie Nokin, Alessia Mira, Enrico Patrucco, Biagio Ricciuti, Sophie Cousin

Nat Commun· August 2024

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IκB kinase-α coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy.
Irene Pecharromán, Laura Solé, Daniel Álvarez-Villanueva, Teresa Lobo-Jarne, Josune Alonso-Marañón

EMBO J· November 2023

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Generation and Integrated Analysis of Advanced Patient-Derived Orthoxenograft Models (PDOX) for the Rational Assessment of Targeted Therapies in Endometrial Cancer.
Laura Devis-Jauregui, August Vidal, Laura Plata-Peña, Maria Santacana, Sandra García-Mulero, Maria Martinez-Iniesta

Adv Sci (Weinh)· November 2022

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A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath Tumors.
Juana Fernández-Rodríguez, Edgar Creus-Bachiller, Xiaohu Zhang, Maria Martínez-Iniesta, Sara Ortega-Bertran

Mol Cancer Ther· July 2022

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p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.
Laura Solé, Teresa Lobo-Jarne, Daniel Álvarez-Villanueva, Josune Alonso-Marañón, Yolanda Guillén

Nat Commun· May 2022

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Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma.
Elisabet Aliagas, Ania Alay, Maria Martínez-Iniesta, Miguel Hernández-Madrigal, David Cordero

Br J Cancer· November 2021

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Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair.
Josune Alonso-Marañón, Alberto Villanueva, Josep Maria Piulats, María Martínez-Iniesta, Laura Solé

Oncogene· August 2021

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Extramedullary multiple myeloma patient-derived orthotopic xenograft with a highly altered genome: combined molecular and therapeutic studies.
Lourdes Farre, Gabriela Sanz, Neus Ruiz-Xivillé, Manuel Castro de Moura, Juan Francisco Martin-Tejera, Maria Martinez-Iniesta

Dis Model Mech· July 2021

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Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor.
Juana Fernández-Rodríguez, Andrés Morales La Madrid, Bernat Gel, Alicia Castañeda Heredia, Héctor Salvador

Ther Adv Med Oncol· July 2020

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Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program.
Maxime Janin, Vanessa Ortiz-Barahona, Manuel Castro de Moura, Anna Martínez-Cardús, Pere Llinàs-Arias

Acta Neuropathol· December 2019

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The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition.
Cristina Oliveira-Mateos, Anaís Sánchez-Castillo, Marta Soler, Aida Obiols-Guardia, David Piñeyro

Nat Commun· September 2019

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IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer.
Carlota Colomer, Pol Margalef, Alberto Villanueva, Anna Vert, Irene Pecharroman, Maria Martinez-Iniesta

Mol Cell· August 2019

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Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent.
Josep M Piulats, August Vidal, Francisco J García-Rodríguez, Clara Muñoz, Marga Nadal

Clin Cancer Res· August 2018

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Tumor xenograft modeling identifies an association between TCF4 loss and breast cancer chemoresistance.
Gorka Ruiz de Garibay, Francesca Mateo, Agostina Stradella, Rafael Valdés-Mas, Luis Palomero, María Martinez-Iniesta

Dis Model Mech· May 2018

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Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer.
Angel Diaz-Lagares, Ana B Crujeiras, Paula Lopez-Serra, Marta Soler, Fernando Setien

Proc Natl Acad Sci U S A· November 2016

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Absence of MxA induction is related to a poor clinical response to interferon beta treatment in multiple sclerosis patients.
Elisabet Matas, Laura Bau, María Martínez-Iniesta, Lucía Romero-Pinel, Maria Alba Mañé-Martínez

J Neurol· April 2016

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MxA mRNA expression as a biomarker of interferon beta response in multiple sclerosis patients.
Elisabet Matas, Laura Bau, María Martínez-Iniesta, Lucía Romero-Pinel, M Alba Mañé-Martínez

J Neuroimmunol· February 2016

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Baseline MxA mRNA expression predicts interferon beta response in multiple sclerosis patients.
Elisabet Matas, Laura Bau, María Martínez-Iniesta, Lucía Romero-Pinel, M Alba Mañé

PLoS One· December 2015

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Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR.
Miguel Vizoso, Humberto J Ferreira, Paula Lopez-Serra, F Javier Carmona, Anna Martínez-Cardús, Maria Martinez-Iniesta

Nat Med· July 2015

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BRAF-induced tumorigenesis is IKKα-dependent but NF-κB-independent.
Pol Margalef, Carlota Colomer, Alberto Villanueva, Clara Montagut, Mar Iglesias

Sci Signal· April 2015

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Lurbinectedin (PM01183), a new DNA minor groove binder, inhibits growth of orthotopic primary graft of cisplatin-resistant epithelial ovarian cancer.
August Vidal, Clara Muñoz, María-José Guillén, Jemina Moretó, Sara Puertas

Clin Cancer Res· October 2012

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A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer.
Pol Margalef, Vanessa Fernández-Majada, Alberto Villanueva, Ricard Garcia-Carbonell, Mar Iglesias

Cell Rep· October 2012

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Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype.
Alvaro Aytes, David G Molleví, Maria Martinez-Iniesta, Marga Nadal, August Vidal

Mol Carcinog· September 2012

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