Publications by authors named "Maria Zajac-Kaye"

Claim this Profile
I
Integrated proteomic analysis identifies TYMS-dependent AMPK-mTOR signaling in pancreatic neuroendocrine tumors.
Vinod Vijayakurup, Benjamin Meyer, Syeda Rida Rizvi, Kara H Kievit, Iram Hyder, Maria Zajac-Kaye

iScience· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CerS2 is a druggable target in triple-negative breast cancer.
Hissah Alatawi, Haritha H Nair, Lingbao Ai, Iqbal Mahmud, Abhishek Gour, Maria Zajac-Kaye

bioRxiv· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PROTAC-mediated dual degradation of BCL-xL and BCL-2 is a highly effective therapeutic strategy in small-cell lung cancer.
Sajid Khan, Lin Cao, Janet Wiegand, Peiyi Zhang, Maria Zajac-Kaye

bioRxiv· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PROTAC-Mediated Dual Degradation of BCL-xL and BCL-2 Is a Highly Effective Therapeutic Strategy in Small-Cell Lung Cancer.
Sajid Khan, Lin Cao, Janet Wiegand, Peiyi Zhang, Maria Zajac-Kaye

Cells· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Corrigendum: Targeting thymidylate synthase enhances the chemosensitivity of triple-negative breast cancer towards 5-FU-based combinatorial therapy.
Nair Hariprasad Haritha, Akbar Nawab, Vinod Vijayakurup, Nikhil Ponnoor Anto, Vijayasteltar B Liju, Maria Zajac-Kaye

Front Oncol· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background.
Maria V Guijarro, Akbar Nawab, Peter Dib, Sandra Burkett, Xiaoping Luo, Maria Zajac-Kaye

Oncogene· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival.
Maria V Guijarro, Patrick C Kellish, Peter E Dib, Nicholas G Paciaroni, Akbar Nawab, Maria Zajac-Kaye

JCI Insight· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Co-targeting BCL-X and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice.
Sajid Khan, Patrick Kellish, Nick Connis, Dinesh Thummuri, Janet Wiegand, Maria Zajac-Kaye

Cell Death Discov· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival.
Vinod Vijayakurup, Kyungah Maeng, Hye Seung Lee, Benjamin Meyer, Sandra Burkett, Maria Zajac-Kaye

JCI Insight· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
BCL-X PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRAS-mutated cancers.
Sajid Khan, Janet Wiegand, Peiyi Zhang, Wanyi Hu, Dinesh Thummuri, Maria Zajac-Kaye

J Hematol Oncol· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy.
Nair Hariprasad Haritha, Akbar Nawab, Vinod Vijayakurup, Nikhil Ponnoor Anto, Vijayasteltar B Liju, Maria Zajac-Kaye

Front Oncol· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma.
Yue Jiang, Ruli Gao, Chunxia Cao, Lauren Forbes, Jianping Li, Maria Zajac-Kaye

Oral Oncol· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Oncolytic virotherapy for small-cell lung cancer induces immune infiltration and prolongs survival.
Patrick Kellish, Daniil Shabashvili, Masmudur M Rahman, Akbar Nawab, Maria V Guijarro, Maria Zajac-Kaye

J Clin Invest· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CDK4/6 inhibition stabilizes disease in patients with p16-null non-small cell lung cancer and is synergistic with mTOR inhibition.
Priya K Gopalan, Andres Gordillo Villegas, Chunxia Cao, Mary Pinder-Schenck, Alberto Chiappori, Maria Zajac-Kaye

Oncotarget· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Microbial marauders: pancreatic microbiota and its impact on carcinogenesis.
Ryan M Thomas, Maria Zajac-Kaye

Ann Transl Med· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models.
Ryan M Thomas, Raad Z Gharaibeh, Josee Gauthier, Mark Beveridge, Jillian L Pope, Maria Zajac-Kaye

Carcinogenesis· July 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations.
Satya Narayan, Aruna S Jaiswal, Ritika Sharma, Akbar Nawab, Lizette Vila Duckworth, Maria Zajac-Kaye

Oncotarget· August 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 Vectors.
Min Chen, Kyungah Maeng, Akbar Nawab, Rony A Francois, Julie K Bray, Maria Zajac-Kaye

Hum Gene Ther Methods· February 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells.
Jianliang Zhang, Di-Hua He, Maria Zajac-Kaye, Steven N Hochwald

Cell Cycle· August 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting Focal Adhesion Kinase and Resistance to mTOR Inhibition in Pancreatic Neuroendocrine Tumors.
Rony A François, Kyungah Maeng, Akbar Nawab, Frederic J Kaye, Steven N Hochwald, Maria Zajac-Kaye

J Natl Cancer Inst· August 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Role of LKB1-CRTC1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer.
Chunxia Cao, Ruli Gao, Min Zhang, Antonio L Amelio, Mohammad Fallahi, Maria Zajac-Kaye

J Natl Cancer Inst· January 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets.
Ruli Gao, Chunxia Cao, Min Zhang, Maria-Cecilia Lopez, Yuanqing Yan, Maria Zajac-Kaye

Oncotarget· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Overexpression of histone deacetylases in cancer cells is controlled by interplay of transcription factors and epigenetic modulators.
Hui Yang, Tal Salz, Maria Zajac-Kaye, Daiqing Liao, Suming Huang

FASEB J· October 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement.
Antonio L Amelio, Mohammad Fallahi, Franz X Schaub, Min Zhang, Mariam B Lawani, Maria Zajac-Kaye

Proc Natl Acad Sci U S A· August 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Analysis of 320 gastroenteropancreatic neuroendocrine tumors identifies TS expression as independent biomarker for survival.
Hye Seung Lee, Min Chen, Ji Hun Kim, Woo Ho Kim, Soyeon Ahn, Maria Zajac-Kaye

Int J Cancer· July 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis