Publications by authors named "Maria Zappala"

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The Role of Nutraceuticals in Chemoprevention and their Therapeutic Effects when used in Combination with Synthetic Drugs.
Carla Di Chio, Fabiola De Luca, Josè Starvaggi, Santo Previti, Maria Zappalà

Curr Med Chem· November 2025

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CAR-T Cell Therapy for Prostate Cancer: Current Advances and Future Perspectives.
Maria Luisa Calabrò, Roberta Ettari, Carla Di Chio, Fabiola De Luca, Santo Previti

Biomedicines· October 2025

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The Role of Nutraceuticals in Age-Related Ocular Diseases.
Josè Starvaggi, Carla Di Chio, Fabiola De Luca, Santo Previti, Maria Zappalà

Molecules· September 2025

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A Second Opportunity for the Peptide-Based Analogues with γ-Lactam at the P1 Position: Human Cathepsin S Inhibition.
Santo Previti, Nunzio Iraci, Elsa Calcaterra, Roberta Ettari, Maria Zappalà

Pharmaceuticals (Basel)· September 2025

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Synthesis and Combination Studies of Novel Dipeptide Nitriles with Curcumin for a Potent Synergistic Action Against Rhodesain, Cysteine Protease of .
Carla Di Chio, Josè Starvaggi, Santo Previti, Fabiola De Luca, Benito Natale

Pharmaceuticals (Basel)· June 2025

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Identification of constrained peptidomimetics carrying a Michael acceptor warhead as antitrypanosomal agents.
Santo Previti, Elsa Calcaterra, Carla Di Chio, Benito Natale, Muhammad Waqas

Eur J Med Chem· April 2025

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Drug Combination Studies of Isoquinolinone AM12 with Curcumin or Quercetin: A New Combination Strategy to Synergistically Inhibit 20S Proteasome.
Carla Di Chio, Santo Previti, Josè Starvaggi, Fabiola De Luca, Maria Luisa Calabrò

Int J Mol Sci· October 2024

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Identification of Dual Inhibitors Targeting Main Protease (M) and Cathepsin L as Potential Anti-SARS-CoV-2 Agents.
Santo Previti, Roberta Ettari, Elsa Calcaterra, Michele Roggia, Benito Natale

ACS Med Chem Lett· May 2024

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The Inhibition of NS2B/NS3 Protease: A New Therapeutic Opportunity to Treat Dengue and Zika Virus Infection.
Josè Starvaggi, Santo Previti, Maria Zappalà, Roberta Ettari

Int J Mol Sci· April 2024

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Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria.
Carla Di Chio, Josè Starvaggi, Noemi Totaro, Santo Previti, Benito Natale

Int J Mol Sci· April 2024

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Influence of amino acid size at the P3 position of N-Cbz-tripeptide Michael acceptors targeting falcipain-2 and rhodesain for the treatment of malaria and human african trypanosomiasis.
Santo Previti, Roberta Ettari, Carla Di Chio, Jenny Legac, Marta Bogacz

Bioorg Chem· August 2023

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Virtual Screening Strategy and In Vitro Tests to Identify New Inhibitors of the Immunoproteasome.
Giulia Culletta, Marco Tutone, Roberta Ettari, Ugo Perricone, Carla Di Chio

Int J Mol Sci· June 2023

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Blunting Neuroinflammation by Targeting the Immunoproteasome with Novel Amide Derivatives.
Chiara Imbesi, Roberta Ettari, Natasha Irrera, Maria Zappalà, Giovanni Pallio

Int J Mol Sci· June 2023

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Dipeptide Nitrile CD34 with Curcumin: A New Improved Combination Strategy to Synergistically Inhibit Rhodesain of .
Carla Di Chio, Santo Previti, Noemi Totaro, Fabiola De Luca, Alessandro Allegra

Int J Mol Sci· May 2023

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Sulfonamide Moiety as "Molecular Chimera" in the Design of New Drugs.
Giulia Culletta, Marco Tutone, Maria Zappalà, Anna Maria Almerico

Curr Med Chem· February 2023

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Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors.
Santo Previti, Roberta Ettari, Elsa Calcaterra, Salvatore Di Maro, Stefan J Hammerschmidt

Eur J Med Chem· February 2023

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Monoclonal Antibodies: The Greatest Resource to Treat Multiple Myeloma.
Fabiola De Luca, Alessandro Allegra, Carla Di Chio, Santo Previti, Maria Zappalà

Int J Mol Sci· February 2023

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Drug Combination Studies of the Dipeptide Nitrile CD24 with Curcumin: A New Strategy to Synergistically Inhibit Rhodesain of .
Carla Di Chio, Santo Previti, Fabiola De Luca, Marta Bogacz, Collin Zimmer

Int J Mol Sci· November 2022

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Drug combination studies of PS-1 and quercetin against rhodesain of .
Carla Di Chio, Santo Previti, Fabiola De Luca, Alessandro Allegra, Maria Zappalà

Nat Prod Res· August 2022

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Dihydrochalcones as Antitumor Agents.
Fabiola De Luca, Carla Di Chio, Maria Zappalà, Roberta Ettari

Curr Med Chem· August 2022

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Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain.
Santo Previti, Roberta Ettari, Elsa Calcaterra, Carla Di Chio, Rahul Ravichandran

ACS Med Chem Lett· July 2022

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Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense.
Carla Di Chio, Santo Previti, Giorgio Amendola, Rahul Ravichandran, Annika Wagner

Eur J Med Chem· June 2022

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Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis.
Santo Previti, Roberta Ettari, Carla Di Chio, Rahul Ravichandran, Marta Bogacz

Molecules· June 2022

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Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF-CEM and Multidrug-Resistant CEM/ADR5000 Leukemia Cells.
Carla Di Chio, Min Zhou, Thomas Efferth, Tanja Schirmeister, Maria Zappalà

Chem Biodivers· February 2022

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Development of isoquinolinone derivatives as immunoproteasome inhibitors.
Roberta Ettari, Nunzio Iraci, Carla Di Chio, Santo Previti, Mariafernanda Danzè

Bioorg Med Chem Lett· January 2022

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