Publications by authors named "Marie-Anne Robin"

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Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG Cell-Based Biosensors to Monitor Hepatocyte Differentiation, Drug Metabolism and Toxicity.
Manuel Vlach, Nicolas Quesnot, Hélène Dubois-Pot-Schneider, Catherine Ribault, Yann Verres, Marie-Anne Robin

Sensors (Basel)· May 2019

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Large-Scale Modeling Approach Reveals Functional Metabolic Shifts during Hepatic Differentiation.
Nathalie Poupin, Anne Corlu, Nicolas J Cabaton, Hélène Dubois-Pot-Schneider, Cécile Canlet, Marie-Anne Robin

J Proteome Res· January 2019

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Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes.
Nicolas Quesnot, Simon Bucher, Christina Gade, Manuel Vlach, Elise Vene, Marie-Anne Robin

Arch Toxicol· October 2018

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Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.
Simon Bucher, Arnaud Tête, Normand Podechard, Marie Liamin, Dounia Le Guillou, Marie-Anne Robin

Sci Rep· April 2018

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Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure.
Simon Bucher, Pégah Jalili, Dounia Le Guillou, Karima Begriche, Karine Rondel, Marie-Anne Robin

Environ Toxicol· March 2017

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A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen.
Anaïs Michaut, Dounia Le Guillou, Caroline Moreau, Simon Bucher, Mitchell R McGill, Marie-Anne Robin

Toxicol Appl Pharmacol· February 2016

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Evaluation of genotoxicity using automated detection of γH2AX in metabolically competent HepaRG cells.
Nicolas Quesnot, Karine Rondel, Marc Audebert, Sophie Martinais, Denise Glaise, Marie-Anne Robin

Mutagenesis· January 2016

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Modulation of metabolizing enzymes by bisphenol a in human and animal models.
Nicolas Quesnot, Simon Bucher, Bernard Fromenty, Marie-Anne Robin

Chem Res Toxicol· September 2014

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Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease.
Anaïs Michaut, Caroline Moreau, Marie-Anne Robin, Bernard Fromenty

Liver Int· August 2014

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Interactions of endosulfan and methoxychlor involving CYP3A4 and CYP2B6 in human HepaRG cells.
Camille C Savary, Rozenn Jossé, Arnaud Bruyère, Fabrice Guillet, Marie-Anne Robin

Drug Metab Dispos· August 2014

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Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice.
Sébastien Anthérieu, Dounia Le Guillou, Cédric Coulouarn, Karima Begriche, Viviane Trak-Smayra, Marie-Anne Robin

Toxicol Appl Pharmacol· April 2014

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Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease.
Karima Begriche, Julie Massart, Marie-Anne Robin, Fabrice Bonnet, Bernard Fromenty

Hepatology· October 2013

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Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells.
Sébastien Anthérieu, Pamela Bachour-El Azzi, Julie Dumont, Ziad Abdel-Razzak, Christiane Guguen-Guillouzo, Marie-Anne Robin

Hepatology· April 2013

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Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice.
Jacinthe Aubert, Karima Begriche, Matthieu Delannoy, Isabelle Morel, Julie Pajaud, Marie-Anne Robin

J Pharmacol Exp Ther· September 2012

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Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver.
Laetitia Knockaert, Alain Berson, Catherine Ribault, Pierre-Emmanuel Prost, Alain Fautrel, Marie-Anne Robin

Lab Invest· March 2012

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Central role of mitochondria in drug-induced liver injury.
Dominique Pessayre, Bernard Fromenty, Alain Berson, Marie-Anne Robin, Philippe Lettéron

Drug Metab Rev· February 2012

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Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds.
Rozenn Josse, Julie Dumont, Alain Fautrel, Marie-Anne Robin, André Guillouzo

Toxicol Appl Pharmacol· January 2012

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Mechanisms of mitochondrial targeting of cytochrome P450 2E1: physiopathological role in liver injury and obesity.
Laetitia Knockaert, Bernard Fromenty, Marie-Anne Robin

FEBS J· November 2011

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Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells.
Sébastien Anthérieu, Alexandra Rogue, Bernard Fromenty, André Guillouzo, Marie-Anne Robin

Hepatology· June 2011

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Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver.
Karima Begriche, Julie Massart, Marie-Anne Robin, Annie Borgne-Sanchez, Bernard Fromenty

J Hepatol· April 2011

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Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen.
Laetitia Knockaert, Véronique Descatoire, Nathalie Vadrot, Bernard Fromenty, Marie-Anne Robin

Toxicol In Vitro· March 2011

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Overexpression of Bcl-2 in hepatocytes protects against injury but does not attenuate fibrosis in a mouse model of chronic cholestatic liver disease.
Claudia Mitchell, Meriem Mahrouf-Yorgov, Alicia Mayeuf, Marie-Anne Robin, Abdellah Mansouri

Lab Invest· February 2011

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Preferential induction of the AhR gene battery in HepaRG cells after a single or repeated exposure to heterocyclic aromatic amines.
Julie Dumont, Rozenn Jossé, Carine Lambert, Sébastien Anthérieu, Véronique Laurent, Marie-Anne Robin

Toxicol Appl Pharmacol· November 2010

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Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells.
Julie Dumont, Rozenn Jossé, Carine Lambert, Sébastien Anthérieu, Ludovic Le Hegarat, Marie-Anne Robin

Toxicol Appl Pharmacol· June 2010

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Protection against hepatocyte mitochondrial dysfunction delays fibrosis progression in mice.
Claudia Mitchell, Marie-Anne Robin, Alicia Mayeuf, Meriem Mahrouf-Yorgov, Abdellah Mansouri

Am J Pathol· November 2009

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