Publications by authors named "Marilyne Labrie"

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ZBP1 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in ovarian cancer.
Shen-Nan Shi, Qiuyang Xu, Zhiqi Liao, Wenjian Gong, Yilin Cui, Marilyne Labrie

Drug Resist Updat· January 2026

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CD8+ T cells in the tumor microenvironment modulate response to endocrine therapy in breast cancer.
Fabiana Napolitano, Yunguan Wang, Dhivya R Sudhan, Paula I Gonzalez-Ericsson, Luigi Formisano, Marilyne Labrie

J Clin Invest· December 2025

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Aurora kinase B phosphorylates ZBP1 to drive PANoptosis following treatment with PARP and ATR inhibitors combination.
Wenjian Gong, Zhiqi Liao, Fan Xiong, Linghui Wang, Shennan Shi, Marilyne Labrie

Nat Commun· November 2025

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Rictor orchestrates β-catenin/FOXO balance by maintaining redox homeostasis during development of ovarian cancer.
Xuejiao Zhao, Huiling Lai, Guannan Li, Yu Qin, Ruqi Chen, Marilyne Labrie

Oncogene· June 2025

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Current preclinical models of brain metastasis.
Zacharie Drouin, Flavie Lévesque, Korina Mouzakitis, Marilyne Labrie

Clin Exp Metastasis· December 2024

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T peripheral helper (Tph) cells, a marker of immune activation in cancer and autoimmune disorders.
Celia Del Carmen Crespo Oliva, Marilyne Labrie, Hugues Allard-Chamard

Clin Immunol· September 2024

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A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies.
Shiyou Wei, Kuang Du, Hongbin Lan, Zhenyu Yang, Yulan Deng, Marilyne Labrie

bioRxiv· September 2024

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Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions.
Eileen O Dareng, Simon G Coetzee, Jonathan P Tyrer, Pei-Chen Peng, Will Rosenow, Marilyne Labrie

Am J Hum Genet· June 2024

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Enhancing anticancer activity of macrophages through rational drug combinations.
Gordon B Mills, Marilyne Labrie

J Clin Invest· May 2024

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The Breast Cancer Proteome and Precision Oncology.
Jonathan T Lei, Eric J Jaehnig, Hannah Smith, Matthew V Holt, Xi Li, Marilyne Labrie

Cold Spring Harb Perspect Med· October 2023

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Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci.
Amber A DeVries, Joe Dennis, Jonathan P Tyrer, Pei-Chen Peng, Simon G Coetzee, Marilyne Labrie

J Natl Cancer Inst· November 2022

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Therapy resistance: opportunities created by adaptive responses to targeted therapies in cancer.
Marilyne Labrie, Joan S Brugge, Gordon B Mills, Ioannis K Zervantonakis

Nat Rev Cancer· June 2022

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Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
Shiyou Wei, Delong Yin, Shengnan Yu, Xiang Lin, Milan R Savani, Marilyne Labrie

Clin Cancer Res· May 2022

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Identification of biomarkers of response to preoperative talazoparib monotherapy in treatment naïve gBRCA+ breast cancers.
Xuan Liu, Zhongqi Ge, Fei Yang, Alejandro Contreras, Sanghoon Lee, Marilyne Labrie

NPJ Breast Cancer· May 2022

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Single-Cell Proteomics Analysis of Recurrent Low-Grade Serous Ovarian Carcinoma and Associated Brain Metastases.
Tanja Pejovic, Pierre-Valérien Abate, Hongli Ma, Jaclyn Thiessen, Christopher L Corless, Marilyne Labrie

Front Oncol· May 2022

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Exceptional Response to Trastuzumab in a Heavily Pretreated Patient With ERBB3-Mutated Metastatic Breast Cancer.
Swapnil Parmar, Jamie M Keck, Ben Kong, Regan Look, Brett Johnson, Marilyne Labrie

JCO Precis Oncol· March 2022

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A multi-encoder variational autoencoder controls multiple transformational features in single-cell image analysis.
Luke Ternes, Mark Dane, Sean Gross, Marilyne Labrie, Gordon Mills

Commun Biol· March 2022

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An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer.
Brett E Johnson, Allison L Creason, Jayne M Stommel, Jamie M Keck, Swapnil Parmar, Marilyne Labrie

Cell Rep Med· February 2022

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Characterization of anticancer drug resistance by reverse-phase protein array: new targets and strategies.
Ann M Cathcart, Hannah Smith, Marilyne Labrie, Gordon B Mills

Expert Rev Proteomics· February 2022

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Phase Ib Dose Expansion and Translational Analyses of Olaparib in Combination with Capivasertib in Recurrent Endometrial, Triple-Negative Breast, and Ovarian Cancer.
Shannon N Westin, Marilyne Labrie, Jennifer K Litton, Aurora Blucher, Yong Fang

Clin Cancer Res· December 2021

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A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.
Shengnan Yu, Shiyou Wei, Milan Savani, Xiang Lin, Kuang Du, Marilyne Labrie

Clin Cancer Res· December 2021

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Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies.
Marilyne Labrie, Allen Li, Allison Creason, Courtney Betts, Jamie Keck

NPJ Precis Oncol· October 2021

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Targeting mTOR signaling overcomes acquired resistance to combined BRAF and MEK inhibition in BRAF-mutant melanoma.
Beike Wang, Wei Zhang, Gao Zhang, Lawrence Kwong, Hezhe Lu, Marilyne Labrie

Oncogene· September 2021

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Characterizing advanced breast cancer heterogeneity and treatment resistance through serial biopsies and comprehensive analytics.
Allen Li, Jamie M Keck, Swapnil Parmar, Janice Patterson, Marilyne Labrie

NPJ Precis Oncol· March 2021

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Systems approach to rational combination therapy: PARP inhibitors.
Chaoyang Sun, Yong Fang, Marilyne Labrie, Xi Li, Gordon B Mills

Biochem Soc Trans· June 2020

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