Publications by authors named "Mario Brosch"

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Hepatic stellate cells control liver zonation, size and functions via R-spondin 3.
Atsushi Sugimoto, Yoshinobu Saito, Guanxiong Wang, Qiuyan Sun, Chuan Yin, Mario Brosch

Nature· April 2025

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Cell atlas of the regenerating human liver after portal vein embolization.
Agnieska Brazovskaja, Tomás Gomes, Rene Holtackers, Philipp Wahle, Christiane Körner, Mario Brosch

Nat Commun· July 2024

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Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease.
Carlotta Mayer, Sophie Nehring, Michael Kücken, Urska Repnik, Sarah Seifert, Mario Brosch

EMBO Rep· September 2023

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Genetic variation in modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study.
Stephan Buch, Hamish Innes, Philipp Ludwig Lutz, Hans Dieter Nischalke, Jens U Marquardt, Mario Brosch

Gut· February 2023

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The HSF1-CPT1a Pathway Is Differentially Regulated in NAFLD Progression.
Wiebke Breternitz, Friedrich Sandkühler, Frauke Grohmann, Jochen Hampe, Mario Brosch

Cells· November 2022

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Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer.
Kenneth Peuker, Anne Strigli, Daniele V F Tauriello, Alexander Hendricks, Witigo von Schönfels, Mario Brosch

Immunity· April 2022

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Nonalcoholic fatty liver disease stratification by liver lipidomics.
Olga Vvedenskaya, Tim Daniel Rose, Oskar Knittelfelder, Alessandra Palladini, Judith Andrea Heidrun Wodke, Mario Brosch

J Lipid Res· March 2022

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Sex-dependent dynamics of metabolism in primary mouse hepatocytes.
Luise Hochmuth, Christiane Körner, Fritzi Ott, Daniela Volke, Kaja Blagotinšek Cokan, Mario Brosch

Arch Toxicol· September 2021

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Loss of hepatic Mboat7 leads to liver fibrosis.
Veera Raghavan Thangapandi, Oskar Knittelfelder, Mario Brosch, Eleonora Patsenker, Olga Vvedenskaya

Gut· May 2021

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SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation.
Lea Južnić, Kenneth Peuker, Anne Strigli, Mario Brosch, Alexander Herrmann

Gut· March 2021

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Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.
Hamish Innes, Stephan Buch, Sharon Hutchinson, Indra Neil Guha, Joanne R Morling, Mario Brosch

Gastroenterology· October 2020

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Shotgun lipidomics-based characterization of the landscape of lipid metabolism in colorectal cancer.
Yuting Wang, Sebastian Hinz, Ortrud Uckermann, Pia Hönscheid, Witigo von Schönfels, Mario Brosch

Biochim Biophys Acta Mol Cell Biol Lipids· March 2020

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Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression.
Fabián Segovia-Miranda, Hernán Morales-Navarrete, Michael Kücken, Vincent Moser, Sarah Seifert, Mario Brosch

Nat Med· December 2019

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Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human.
Erik Kolbe, Susanne Aleithe, Christiane Rennert, Luise Spormann, Fritzi Ott, Mario Brosch

Cell Rep· December 2019

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Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis.
Pavel Strnad, Stephan Buch, Karim Hamesch, Janett Fischer, Jonas Rosendahl, Mario Brosch

Gut· June 2019

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Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms.
Clemens Schafmayer, James William Harrison, Stephan Buch, Christina Lange, Matthias C Reichert, Mario Brosch

Gut· May 2019

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Evolutionary Distance Predicts Recurrence After Liver Transplantation in Multifocal Hepatocellular Carcinoma.
Nils Heits, Mario Brosch, Alexander Herrmann, Robin Behrens, Christoph Röcken

Transplantation· October 2018

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Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control.
Mario Brosch, Kathrin Kattler, Alexander Herrmann, Witigo von Schönfels, Karl Nordström

Nat Commun· October 2018

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Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers.
Felix Kordowski, Julia Kolarova, Clemens Schafmayer, Stephan Buch, Torsten Goldmann, Mario Brosch

BMC Cancer· August 2018

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Dynamics of epigenetic age following hematopoietic stem cell transplantation.
Friedrich Stölzel, Mario Brosch, Steve Horvath, Michael Kramer, Christian Thiede

Haematologica· August 2017

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Translational learning from clinical studies predicts drug pharmacokinetics across patient populations.
Markus Krauss, Ute Hofmann, Clemens Schafmayer, Svitlana Igel, Jan Schlender, Mario Brosch

NPJ Syst Biol Appl· March 2017

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Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.
Simone Wahl, Alexander Drong, Benjamin Lehne, Marie Loh, William R Scott, Mario Brosch

Nature· January 2017

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Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients.
Andreas Teufel, Timo Itzel, Wiebke Erhart, Mario Brosch, Xiao Yu Wang

Gastroenterology· September 2016

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A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis.
Stephan Buch, Felix Stickel, Eric Trépo, Michael Way, Alexander Herrmann, Mario Brosch

Nat Genet· December 2015

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Obesity accelerates epigenetic aging of human liver.
Steve Horvath, Wiebke Erhart, Mario Brosch, Ole Ammerpohl, Witigo von Schönfels

Proc Natl Acad Sci U S A· October 2014

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