Publications by authors named "Mario Delmar"

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Adeno-associated virus-mediated PKP2 gene therapy confers robust exercise tolerance in a murine model of arrhythmogenic cardiomyopathy.
Marina Cerrone, Sarah Boyce, Mingliang Zhang, Manuela Gencarelli, Mario Delmar

Heart Rhythm· November 2025

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Arrhythmogenic Cardiomyopathy: Towards Genotype Based Diagnoses and Management.
Steven A Muller, Giorgia Bertoli, Jianan Wang, Alessio Gasperetti, Moniek G P J Cox, Mario Delmar

J Cardiovasc Electrophysiol· October 2025

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Exercise-induced dysregulation of the adrenergic response in a mouse model of PKP2-arrhythmogenic cardiomyopathy.
Chantal J M van Opbergen, Lilian K Gutierrez, Giorgia Bertoli, Mingliang Zhang, Sarah Boyce, Mario Delmar

Heart Rhythm· October 2025

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Cardiomyocyte-specific plakophilin-2 loss is sufficient to induce aging and senescence of nonmyocytes. Relevance to arrhythmogenic cardiomyopathy.
Giorgia Bertoli, Kavya Phadke, Alessandro Cospito, Joanna Abi Rizk, Mingliang Zhang, Mario Delmar

bioRxiv· October 2025

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Epicardial contributions to fibro-inflammatory signaling in a Pkp2-deficient arrhythmogenic cardiomyopathy model.
Daniel D Han, Alan C Brooks, Cameron D Baker, Ronald A Dirkx, Deanne M Mickelsen, Mario Delmar

bioRxiv· October 2025

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Atrial cardiomyopathy resulting from loss of plakophilin-2 expression: Response to adrenergic stimulation and implications for the exercise response.
Kavya Phadke, Sergio D'Anna, Estefania Torres Vega, Junhua Xiao, Xianming Lin, Mario Delmar

J Physiol· September 2025

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Long-Term Follow-Up Data on Flecainide Use as an Antiarrhythmic in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multicenter Study.
Sean Gaine, Thomas Rolland, Babken Asatryan, Mikael Laredo, James Sampognaro, Mario Delmar

JACC Clin Electrophysiol· June 2025

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Junctions Speak in Volumes: The Role of the Intercellular Space in Cardiac Cell-Cell Propagation.
Mario Delmar, Xianming Lin

JACC Clin Electrophysiol· May 2025

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Meeting report - Alpine desmosome disease meeting 2024: advances and emerging topics in desmosomes and related diseases.
Jens Waschke, Masayuki Amagai, Christoph Becker, Mario Delmar, Firat Duru

J Cell Sci· January 2025

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Describing cardiac anatomy: The truth is staring us in the face.
Travis D Richardson, Zachi Itzhak Attia, Ehud Chorin, Mario Delmar, Luigi Di Biase

Heart Rhythm· December 2024

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Arrhythmia Research at a Tipping Point: The Need for Disruptive Science and Technology.
Paul J Wang, Glenn I Fishman, Lee Eckhardt, Joseph C Wu, Mario Delmar

Circ Arrhythm Electrophysiol· August 2024

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AAV-Mediated Delivery of Plakophilin-2a Arrests Progression of Arrhythmogenic Right Ventricular Cardiomyopathy in Murine Hearts: Preclinical Evidence Supporting Gene Therapy in Humans.
Chantal J M van Opbergen, Bitha Narayanan, Chester B Sacramento, Katie M Stiles, Vartika Mishra, Mario Delmar

Circ Genom Precis Med· February 2024

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Outlining cardiac ion channel protein interactors and their signature in the human electrocardiogram.
Svetlana Maurya, Robert W Mills, Konstantin Kahnert, David Y Chiang, Giorgia Bertoli, Mario Delmar

Nat Cardiovasc Res· July 2023

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The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes.
Morten S Nielsen, Chantal J M van Opbergen, Toon A B van Veen, Mario Delmar

Physiol Rev· July 2023

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Nanogold based protein localization enables subcellular visualization of cell junction protein by SBF-SEM.
Feng-Xia Liang, Joseph Sall, Chris Petzold, Chantal J M van Opbergen, Xiangxi Liang, Mario Delmar

Methods Cell Biol· July 2023

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Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments.
Luc Leybaert, Maarten Aj De Smet, Alessio Lissoni, Rosalie Allewaert, H Llewelyn Roderick, Mario Delmar

J Clin Invest· March 2023

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Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC.
Marta Pérez-Hernández, Chantal J M van Opbergen, Navratan Bagwan, Christoffer Rasmus Vissing, Grecia M Marrón-Liñares, Mario Delmar

Circulation· September 2022

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The Genetics of Brugada Syndrome.
Marina Cerrone, Sarah Costa, Mario Delmar

Annu Rev Genomics Hum Genet· August 2022

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Preserved cardiac performance and adrenergic response in a rabbit model with decreased ryanodine receptor 2 expression.
Jingjing Zheng, Holly C Dooge, Marta Pérez-Hernández, Yan-Ting Zhao, Xi Chen, Mario Delmar

J Mol Cell Cardiol· June 2022

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Subcellular trafficking and endocytic recycling of K channels.
Hua-Qian Yang, Fabio A Echeverry, Assmaa ElSheikh, Ivan Gando, Sophia Anez Arredondo, Mario Delmar

Am J Physiol Cell Physiol· June 2022

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Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility.
Julien Barc, Rafik Tadros, Charlotte Glinge, David Y Chiang, Mariam Jouni, Mario Delmar

Nat Genet· May 2022

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Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2-Deficient Hearts.
Chantal J M van Opbergen, Navratan Bagwan, Svetlana R Maurya, Joon-Chul Kim, Abigail N Smith, Mario Delmar

Circulation· May 2022

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Luminal Oxidative Regulation of the Ryanodine Receptor: More Sides to the Story?
Chantal J M van Opbergen, Marta Pérez-Hernández, Mario Delmar

Circ Res· March 2022

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Beta-blocker/ACE inhibitor therapy differentially impacts the steady state signaling landscape of failing and non-failing hearts.
Andrea Sorrentino, Navratan Bagwan, Nora Linscheid, Pi C Poulsen, Konstantin Kahnert, Mario Delmar

Sci Rep· March 2022

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"Orphan" Connexin43 in Plakophilin-2 Deficient Hearts Revealed by Volume Electron Microscopy.
Chantal J M van Opbergen, Joseph Sall, Chris Petzold, Kristen Dancel-Manning, Mario Delmar

Front Cell Dev Biol· March 2022

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