Publications by authors named "Mario Fraga"

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The miR-200 family in the context of obesity and type 2 diabetes.
Carmen Lambert, Elsa Villa-Fernández, Ana Victoria García, Miguel García-Villarino, Judit Fernández, Mario F Fraga

Diabetes Res Clin Pract· November 2025

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Microglial Replacement Reverses Age-Associated Epigenetic Modifications Despite Accelerating Epigenetic Age.
Maria Arbaizar-Rovirosa, Raúl F Pérez, Alfonso Peñarroya, Mattia Gallizioli, Mario F Fraga

Aging Dis· October 2025

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Age-dependent effect of environmental enrichment on the neural 3D chromatin interactome.
Javier Gancedo-Verdejo, Rocío G Urdinguio, Juan Ramón Tejedor, Raúl F Pérez, Alfonso Peñarroya, Mario F Fraga

Cell Rep· September 2025

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HDAC7 induction combined with standard-of-care chemotherapy provides a therapeutic advantage in t(4;11) infant B-cell acute lymphoblastic leukemia.
Oriol de Barrios, Ingrid Ocón-Gabarró, Mar Gusi-Vives, Olga Collazo, Ainara Meler, Mario F Fraga

Biomark Res· July 2025

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Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes.
Carlota Arenillas, Lucía Celada, José Ruiz-Cantador, Bruna Calsina, Debayan Datta, Mario F Fraga

Cancer Discov· May 2025

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Chromatin Preparation from Frozen Tissues for Chromatin Immunoprecipitation (ChIP) Assays.
Virginia López Martínez, Mario Fernández Fraga

Methods Mol Biol· May 2025

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Epigenomic Profiling of Histone Posttranslational Modifications in Frozen Cancer Tissue Using CUT&RUN.
Annalisa Roberti, Mario Fernández Fraga

Methods Mol Biol· May 2025

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Advancing Personalized Medicine in Alzheimer's Disease: Liquid Biopsy Epigenomics Unveil ε4-Linked Methylation Signatures.
Mónica Macías, Juan José Alba-Linares, Blanca Acha, Idoia Blanco-Luquin, Agustín F Fernández, Mario F Fraga

Int J Mol Sci· April 2025

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Epitranscriptomics in the Glioma Context: A Brief Overview.
Pablo Santamarina-Ojeda, Agustín F Fernández, Mario F Fraga

Cancers (Basel)· February 2025

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Integration of multi-omics layers empowers precision diagnosis through unveiling pathogenic mechanisms on maple syrup urine disease.
Juan Ramón Tejedor, Alejandro Soriano-Sexto, Leonardo Beccari, Natalia Castejón-Fernández, Patricia Correcher, Mario F Fraga

J Inherit Metab Dis· January 2025

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NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression.
Belén Lopez-Millan, Alba Rubio-Gayarre, Meritxell Vinyoles, Juan L Trincado, Mario F Fraga

Blood· November 2024

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Epigenetic Study of Cohort of Monozygotic Twins With Hypertrophic Cardiomyopathy Due to MYBPC3 (Cardiac Myosin-Binding Protein C).
Alfonso Peñarroya, Rebeca Lorca, José Julián Rodríguez Reguero, Juan Gómez, Pablo Avanzas, Mario F Fraga

J Am Heart Assoc· November 2024

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DNA Methylation Analysis by Bisulfite Pyrosequencing of Mouse Embryonic Fibroblasts with Reprogramming Enhanced by Thyroid Hormones.
Pablo Santamarina-Ojeda, Agustín F Fernández, Mario F Fraga, Raúl F Pérez

Methods Mol Biol· November 2024

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The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis.
Maria Mercado-Gómez, Naroa Goikoetxea-Usandizaga, Annarein J C Kerbert, Leire Uraga Gracianteparaluceta, Marina Serrano-Maciá, Mario F Fraga

Metabolism· September 2024

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PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas.
Tamara Cubiella, Lucía Celada, Jaime San-Juan-Guardado, Raúl Rodríguez-Aguilar, Álvaro Suárez-Priede, Mario F Fraga

J Pathol· August 2024

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A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment.
Raúl F Pérez, Patricia Tezanos, Alfonso Peñarroya, Alejandro González-Ramón, Rocío G Urdinguio, Mario F Fraga

Nat Commun· July 2024

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Novel 14q32.2 paternal deletion encompassing the whole DLK1 gene associated with Temple syndrome.
Neus Baena, David Monk, Cinthia Aguilera, Mario F Fraga, Agustín F Fernández

Clin Epigenetics· May 2024

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A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma.
Verónica Rey, Juan Tornín, Juan Jose Alba-Linares, Cristina Robledo, Dzohara Murillo, Mario F Fraga

EBioMedicine· April 2024

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Metformin and Glucose Concentration as Limiting Factors in Retinal Pigment Epithelial Cell Viability and Proliferation.
Elsa Villa-Fernández, Ana Victoria García, Alejandra Fernández-Fernández, Miguel García-Villarino, Jessica Ares-Blanco, Mario F Fraga

Int J Mol Sci· February 2024

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ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer.
Irene Fernandez-De-Los-Reyes, Marisa Gomez-Dorronsoro, Iñaki Monreal-Santesteban, Agustín Fernandez-Fernandez, Mario Fraga

Clin Epigenetics· December 2023

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The thyroid hormone enhances mouse embryonic fibroblasts reprogramming to pluripotent stem cells: role of the nuclear receptor corepressor 1.
Constanza Contreras-Jurado, Ana Montero-Pedrazuela, Raúl F Pérez, Susana Alemany, Mario F Fraga

Front Endocrinol (Lausanne)· December 2023

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A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features.
Clara Bueno, Raul Torres-Ruiz, Talia Velasco-Hernandez, Oscar Molina, Paolo Petazzi, Mario F Fraga

Blood· November 2023

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A complex interplay between H2A.Z and HP1 isoforms regulates pericentric heterochromatin.
Jessica González, Laia Bosch-Presegué, Anna Marazuela-Duque, Anna Guitart-Solanes, María Espinosa-Alcantud, Mario F Fraga

Front Cell Dev Biol· November 2023

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DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype.
Estefania Cuesta-Borràs, Cándida Salvans, Oriol Arqués, Irene Chicote, Lorena Ramírez, Mario F Fraga

Cell Rep· August 2023

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CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer.
Juan Ramón Tejedor, Alfonso Peñarroya, Javier Gancedo-Verdejo, Pablo Santamarina-Ojeda, Raúl F Pérez, Mario F Fraga

Clin Epigenetics· August 2023

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