Publications by authors named "Mario Mellado"

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Cholesterol oxidase treatment impairs CXCR4-mediated T cell migration.
Sofía R Gardeta, Eva M García-Cuesta, Blanca Soler Palacios, Rosa Ayala Bueno, Adriana Quijada-Freire, Mario Mellado

Cell Commun Signal· October 2025

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Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain.
Eva M García-Cuesta, Pablo Martínez, Karthik Selvaraju, Gabriel Ulltjärn, Adrián Miguel Gómez Pozo, Mario Mellado

Elife· September 2024

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The complex nature of CXCR4 mutations in WHIM syndrome.
José Miguel Rodríguez-Frade, Luis Ignacio González-Granado, César A Santiago, Mario Mellado

Front Immunol· July 2024

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TrackAnalyzer: A Fiji/ImageJ toolbox for a holistic analysis of tracks.
Ana Cayuela López, Eva M García-Cuesta, Sofía R Gardeta, José Miguel Rodríguez-Frade, Mario Mellado

Biol Imaging· October 2023

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Growth hormone remodels the 3D-structure of the mitochondria of inflammatory macrophages and promotes metabolic reprogramming.
Blanca Soler Palacios, Ricardo Villares, Pilar Lucas, José Miguel Rodríguez-Frade, Ana Cayuela, Mario Mellado

Front Immunol· July 2023

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Sphingomyelin Depletion Inhibits CXCR4 Dynamics and CXCL12-Mediated Directed Cell Migration in Human T Cells.
Sofía R Gardeta, Eva M García-Cuesta, Gianluca D'Agostino, Blanca Soler Palacios, Adriana Quijada-Freire, Mario Mellado

Front Immunol· August 2022

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Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients.
Eva M García-Cuesta, José Miguel Rodríguez-Frade, Sofía R Gardeta, Gianluca D'Agostino, Pablo Martínez, Mario Mellado

Proc Natl Acad Sci U S A· May 2022

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A set point in the selection of the αβTCR T cell repertoire imposed by pre-TCR signaling strength.
Elena R Bovolenta, Eva M García-Cuesta, Lydia Horndler, Julia Ponomarenko, Wolfgang W Schamel, Mario Mellado

Proc Natl Acad Sci U S A· May 2022

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Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL.
Manuel Olazábal-Morán, Miriam Sánchez-Ortega, Laura Martínez-Muñoz, Carmen Hernández, Manuel S Rodríguez, Mario Mellado

Cells· October 2021

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Editorial: Atypical Functions of Leukocyte Chemoattractant Receptors.
José Luis Rodríguez-Fernández, Mario Mellado, Marcus Thelen, Philip M Murphy

Front Immunol· June 2021

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Identification of a Human Polymorphism That Predicts Rheumatoid Arthritis Severity.
Amalia Lamana, Ricardo Villares, Iria V Seoane, Nuria Andrés, Pilar Lucas, Mario Mellado

Front Immunol· April 2021

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Growth Hormone Reprograms Macrophages toward an Anti-Inflammatory and Reparative Profile in an MAFB-Dependent Manner.
Blanca Soler Palacios, Concha Nieto, Pilar Fajardo, Arturo González de la Aleja, Nuria Andrés, Mario Mellado

J Immunol· August 2020

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The multilayered complexity of the chemokine receptor system.
Gianluca D'Agostino, Eva M García-Cuesta, Rosa P Gomariz, José Miguel Rodríguez-Frade, Mario Mellado

Biochem Biophys Res Commun· July 2020

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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity.
Álvaro Teijeira, Saray Garasa, María Gato, Carlos Alfaro, Itziar Migueliz, Mario Mellado

Immunity· May 2020

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A Clinical Approach for the Use of VIP Axis in Inflammatory and Autoimmune Diseases.
Carmen Martínez, Yasmina Juarranz, Irene Gutiérrez-Cañas, Mar Carrión, Selene Pérez-García, Mario Mellado

Int J Mol Sci· December 2019

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Inhibitory Role of Growth Hormone in the Induction and Progression Phases of Collagen-Induced Arthritis.
Ricardo Villares, Gabriel Criado, Yasmina Juarranz, Mercedes Lopez-Santalla, Eva M García-Cuesta, Mario Mellado

Front Immunol· August 2019

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The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases.
Eva M García-Cuesta, César A Santiago, Jesús Vallejo-Díaz, Yasmina Juarranz, José Miguel Rodríguez-Frade, Mario Mellado

Front Endocrinol (Lausanne)· August 2019

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Wnt and RUNX2 mediate cartilage breakdown by osteoarthritis synovial fibroblast-derived ADAMTS-7 and -12.
Selene Pérez-García, Mar Carrión, Raúl Villanueva-Romero, Tamara Hermida-Gómez, Mercedes Fernández-Moreno, Mario Mellado

J Cell Mol Med· June 2019

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Image Processing Protocol for the Analysis of the Diffusion and Cluster Size of Membrane Receptors by Fluorescence Microscopy.
Carlos Oscar S Sorzano, Laura Martínez-Muñoz, Graciela Cascio, Eva M García-Cuesta, J Vargas, Mario Mellado

J Vis Exp· April 2019

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Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function.
Laura Martínez-Muñoz, José Miguel Rodríguez-Frade, Rubén Barroso, Carlos Óscar S Sorzano, Juan A Torreño-Pina, Mario Mellado

Mol Cell· September 2018

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Remodeling our concept of chemokine receptor function: From monomers to oligomers.
Laura Martínez-Muñoz, Ricardo Villares, José Luis Rodríguez-Fernández, José Miguel Rodríguez-Frade, Mario Mellado

J Leukoc Biol· August 2018

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Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function.
Laura Martínez-Muñoz, José Miguel Rodríguez-Frade, Rubén Barroso, Carlos Óscar S Sorzano, Juan A Torreño-Pina, Mario Mellado

Mol Cell· April 2018

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High mobility group box 1 orchestrates tissue regeneration via CXCR4.
Mario Tirone, Ngoc Lan Tran, Chiara Ceriotti, Andrea Gorzanelli, Monica Canepari, Mario Mellado

J Exp Med· January 2018

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The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage.
Annalisa Del Prete, Laura Martínez-Muñoz, Cristina Mazzon, Lara Toffali, Francesca Sozio, Mario Mellado

Blood· September 2017

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Use of Lentiviral Particles As a Cell Membrane-Based mFasL Delivery System for Treatment of Inflammatory Arthritis.
José M Rodríguez-Frade, Anabel Guedán, Pilar Lucas, Laura Martínez-Muñoz, Ricardo Villares, Mario Mellado

Front Immunol· April 2017

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