Publications by authors named "Mario Mikula"

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mTORC2 inhibition reduces tumor burden via STAT1 activation and enhanced response to anti-PD-L1 therapy.
Anna Gschwendtner, Birgit Schütz, Madalina A Mirea, Oliver Eckel, Mikolaj Z Kepa, Mario Mikula

Cell Death Dis· December 2025

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Expression of the cholesterol transporter SR-B1 in melanoma cells facilitates inflammatory signaling leading to reduced cholesterol synthesis.
Oliver Eckel, Madalina A Mirea, Anna Gschwendtner, Martina Pistek, Katharina Kinslechner, Mario Mikula

Neoplasia· May 2025

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Late stage melanoma is hallmarked by low NLGN4X expression leading to HIF1A accumulation.
David Schörghofer, Laurenz Vock, Madalina A Mirea, Oliver Eckel, Anna Gschwendtner, Mario Mikula

Br J Cancer· August 2024

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Dynamic regulation of tumour progression by phenotype-switching drivers.
Laurenz Vock, Anna Gschwendtner, Oliver Eckel, Madalina A Mirea, Markus Hengstschläger, Mario Mikula

Clin Transl Med· July 2022

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Proteome analysis of NRF2 inhibition in melanoma reveals CD44 up-regulation and increased apoptosis resistance upon vemurafenib treatment.
Hans Peter Weitzenböck, Anna Gschwendtner, Christoph Wiesner, Maren Depke, Frank Schmidt, Mario Mikula

Cancer Med· February 2022

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Plasma Membrane Lipids: An Important Binding Site for All Lipoprotein Classes.
Markus Axmann, Birgit Plochberger, Mario Mikula, Florian Weber, Witta Monika Strobl

Membranes (Basel)· November 2021

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STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway.
Alexander Swoboda, Robert Soukup, Oliver Eckel, Katharina Kinslechner, Bettina Wingelhofer, Mario Mikula

Oncogene· February 2021

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Insights into Differentiation of Melanocytes from Human Stem Cells and Their Relevance for Melanoma Treatment.
Madalina A Mirea, Stefan Eckensperger, Markus Hengstschläger, Mario Mikula

Cancers (Basel)· September 2020

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Metabolism of cholesterol and progesterone is differentially regulated in primary trophoblastic subtypes and might be disturbed in recurrent miscarriages.
Sigrid Vondra, Victoria Kunihs, Tanja Eberhart, Karin Eigner, Raimund Bauer, Mario Mikula

J Lipid Res· November 2019

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Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis.
Karl Katholnig, Birgit Schütz, Stephanie D Fritsch, David Schörghofer, Monika Linke, Mario Mikula

JCI Insight· October 2019

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Retraction Note: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.
Tahereh Javaheri, Zahra Kazemi, Jan Pencik, Ha T T Pham, Maximilian Kauer, Mario Mikula

Cell Death Dis· August 2019

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Loss of SR-BI Down-Regulates MITF and Suppresses Extracellular Vesicle Release in Human Melanoma.
Katharina Kinslechner, Birgit Schütz, Martina Pistek, Philipp Rapolter, Hans P Weitzenböck, Mario Mikula

Int J Mol Sci· March 2019

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Genome amplification and cellular senescence are hallmarks of human placenta development.
Philipp Velicky, Gudrun Meinhardt, Kerstin Plessl, Sigrid Vondra, Tamara Weiss, Mario Mikula

PLoS Genet· October 2018

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Regeneration of injured tissue: stem cell dynamics at interplay with mTORC1.
Mario Mikula

Stem Cell Investig· August 2018

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Correction: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.
Tahereh Javaheri, Zahra Kazemi, Jan Pencik, Ha T T Pham, Maximilian Kauer, Mario Mikula

Cell Death Dis· July 2018

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Malignant Phenotypes in Metastatic Melanoma are Governed by SR-BI and its Association with Glycosylation and STAT5 Activation.
Katharina Kinslechner, David Schörghofer, Birgit Schütz, Maria Vallianou, Bettina Wingelhofer, Mario Mikula

Mol Cancer Res· January 2018

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The unfolded protein response impacts melanoma progression by enhancing FGF expression and can be antagonized by a chemical chaperone.
Karin Eigner, Yüksel Filik, Florian Mark, Birgit Schütz, Günter Klambauer, Mario Mikula

Sci Rep· December 2017

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Rapamycin Maintains the Chondrocytic Phenotype and Interferes with Inflammatory Cytokine Induced Processes.
Andrea De Luna-Preitschopf, Hannes Zwickl, Stefan Nehrer, Markus Hengstschläger, Mario Mikula

Int J Mol Sci· July 2017

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Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression.
Monika Linke, Ha Thi Thanh Pham, Karl Katholnig, Thomas Schnöller, Anne Miller, Mario Mikula

Nat Immunol· March 2017

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Generation of metastatic melanoma specific antibodies by affinity purification.
Birgit Schütz, Anita Koppensteiner, David Schörghofer, Katharina Kinslechner, Gerald Timelthaler, Mario Mikula

Sci Rep· November 2016

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Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.
Tahereh Javaheri, Zahra Kazemi, Jan Pencik, Ha Tt Pham, Maximilian Kauer, Mario Mikula

Cell Death Dis· October 2016

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Rapamycin-Induced Hypoxia Inducible Factor 2A Is Essential for Chondrogenic Differentiation of Amniotic Fluid Stem Cells.
Andrea Preitschopf, David Schörghofer, Katharina Kinslechner, Birgit Schütz, Hannes Zwickl, Mario Mikula

Stem Cells Transl Med· May 2016

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Effects of the mTOR inhibitor everolimus and the PI3K/mTOR inhibitor NVP-BEZ235 in murine acute lung injury models.
Sevdican Üstün, Caroline Lassnig, Andrea Preitschopf, Mario Mikula, Mathias Müller

Transpl Immunol· September 2015

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The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence.
David Schörghofer, Katharina Kinslechner, Andrea Preitschopf, Birgit Schütz, Clemens Röhrl, Mario Mikula

Reprod Biol Endocrinol· August 2015

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mTORC1 is essential for early steps during Schwann cell differentiation of amniotic fluid stem cells and regulates lipogenic gene expression.
Andrea Preitschopf, Kongzhao Li, David Schörghofer, Katharina Kinslechner, Birgit Schütz, Mario Mikula

PLoS One· May 2015

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