Publications by authors named "Mario Milani"

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Structure, substrate recognition and therapeutic targeting of the human ADAMTS-5 spacer domain.
Mario Milani, Michela Visintin, Ivet Krastanova, Marco Visentini, Elisa Margotti

Acta Crystallogr D Struct Biol· January 2026

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Aryl Guanyl Hydrazones: A Viable Strategy for Designing BBB-Permeable, Neuroactive Compounds?
Eleonora Colombo, Leonardo Maiorana, Greta Donati, Andrea Menegon, Nicoletta Collura, Mario Milani

ACS Chem Neurosci· August 2025

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Identification of new selective CD36 inhibitors to potentiate HER2-targeted therapy in HER2-positive breast cancer.
Lorenzo Castagnoli, Francesco Bonì, Martina Bigliardi, Paolo Toneguzzo, Paola A Corsetto, Mario Milani

Sci Rep· August 2025

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Structural snapshots of the aldol condensation reaction of the enzyme trans-o-hydroxybenzylidenepyruvate hydratase-aldolase from Pseudomonas fluorescens N3.
Silvia Ferrara, Bianca Braggiotti, Eloise Mastrangelo, Patrizia Di Gennaro, Giovanni Bertoni, Mario Milani

Biochem Biophys Res Commun· February 2025

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Stabilization of the retromer complex: Analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface.
Elisa Fagnani, Francesco Bonì, Pierfausto Seneci, Davide Gornati, Luca Muzio, Mario Milani

Comput Struct Biotechnol J· December 2024

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The antipsychotic drug lurasidone inhibits coronaviruses by affecting multiple targets.
Sara Baroni, Tea Carletti, Manuela Donalisio, Irene Arduino, Irene Cazzaniga, Mario Milani

Front Cell Infect Microbiol· December 2024

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4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses.
Michela Puxeddu, Manuela Donalisio, Joachim Jakob Bugert, Angela Corona, Paolo Cocomazzi, Mario Milani

ACS Infect Dis· September 2024

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Acid-sensing ion channel 3 is a new potential therapeutic target for the control of glioblastoma cancer stem cells growth.
Andrea Balboni, Camilla D'Angelo, Nicoletta Collura, Simone Brusco, Claudia Di Berardino, Mario Milani

Sci Rep· September 2024

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CHCHD4 binding affects the active site of apoptosis inducing factor (AIF): Structural determinants for allosteric regulation.
Elisa Fagnani, Paolo Cocomazzi, Sara Pellegrino, Gabriella Tedeschi, Francesca Grassi Scalvini, Mario Milani

Structure· May 2024

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A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Kevin P Guay, Roberta Ibba, J L Kiappes, Snežana Vasiljević, Francesco Bonì, Mario Milani

iScience· October 2023

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Occupational Accidents Among Search and Rescue Providers During Mountain Rescue Operations and Training Events.
Mario Milani, Giulia Roveri, Marika Falla, Tomas Dal Cappello, Giacomo Strapazzon

Ann Emerg Med· June 2023

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Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses.
Rafaela Milan Bonotto, Francesco Bonì, Mario Milani, Antonio Chaves-Sanjuan, Silvia Franze

Viruses· May 2022

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A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation.
Michela Bollati, Luisa Diomede, Toni Giorgino, Carmina Natale, Elisa Fagnani, Mario Milani

Comput Struct Biotechnol J· November 2021

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Structure-based identification of a new IAP-targeting compound that induces cancer cell death inducing NF-κB pathway.
Federica Cossu, Simone Camelliti, Daniele Lecis, Luca Sorrentino, Maria Teresa Majorini, Mario Milani

Comput Struct Biotechnol J· November 2021

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Synthesis and Characterization of Novel Mono- and Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult.
Davide Gornati, Roselia Ciccone, Antonio Vinciguerra, Stefania Ippati, Anna Pannaccione, Mario Milani

J Med Chem· June 2021

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Combined in silico and in vitro approaches identified the antipsychotic drug lurasidone and the antiviral drug elbasvir as SARS-CoV2 and HCoV-OC43 inhibitors.
Mario Milani, Manuela Donalisio, Rafaela Milan Bonotto, Edoardo Schneider, Irene Arduino

Antiviral Res· May 2021

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Determination of Death in Mountain Rescue: Recommendations of the International Commission for Mountain Emergency Medicine (ICAR MedCom).
Corinna A Schön, Les Gordon, Natalie Hölzl, Mario Milani, Peter Paal

Wilderness Environ Med· December 2020

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Missense mutations affecting Ca-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties.
Giuditta Dal Cortivo, Valerio Marino, Francesco Bonì, Mario Milani, Daniele Dell'Orco

Biochim Biophys Acta Mol Cell Res· October 2020

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Computational and Experimental Characterization of NF023, A Candidate Anticancer Compound Inhibiting cIAP2/TRAF2 Assembly.
Federica Cossu, Luca Sorrentino, Elisa Fagnani, Mattia Zaffaroni, Mario Milani

J Chem Inf Model· October 2020

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Modulation of Guanylate Cyclase Activating Protein 1 (GCAP1) Dimeric Assembly by Ca or Mg: Hints to Understand Protein Activity.
Francesco Bonì, Valerio Marino, Carlo Bidoia, Eloise Mastrangelo, Alberto Barbiroli, Mario Milani

Biomolecules· October 2020

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Histopathological Study of a Broad Spectrum of Skin Dermatoses in Patients Affected or Highly Suspected of Infection by COVID-19 in the Northern Part of Italy: Analysis of the Many Faces of the Viral-Induced Skin Diseases in Previous and New Reported Cases.
Raffaele Gianotti, Sebastiano Recalcati, Fabrizio Fantini, Cristina Riva, Mario Milani

Am J Dermatopathol· August 2020

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Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis.
Luca Muzio, Riccardo Sirtori, Davide Gornati, Simona Eleuteri, Andrea Fossaghi, Mario Milani

Nat Commun· July 2020

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An alternative non-proteolytic mechanism may underlie AGel amyloidosis.
Francesco Bonì, Mario Milani, Eloise Mastrangelo, Alberto Babiroli, Luisa Diomede

Amyloid· January 2020

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The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Matteo de Rosa, Alberto Barbiroli, Francesco Bonì, Emanuele Scalone, Davide Mattioni, Mario Milani

Eur Biophys J· January 2020

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High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion.
Michela Bollati, Emanuele Scalone, Francesco Bonì, Eloise Mastrangelo, Toni Giorgino, Mario Milani

Biochem Biophys Res Commun· October 2019

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