Publications by authors named "Mario Tschan"

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CDX2 loss in colorectal cancer cells is associated with invasive properties and tumor budding.
Nils Bodmer, Kristin Uth, Rina Mehmeti, Cansaran Saygili Demir, Deborah Stroka, Mario P Tschan

Sci Rep· July 2025

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Correction: Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer.
Anna Wojtalla, Barbara Fischer, Nataliya Kotelevets, Francesco A Mauri, Jens Sobek, Mario P Tschan

Clin Cancer Res· February 2025

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Reliable hexokinase 3 protein detection in human cell lines and primary tissue.
Yasmeen H Mady, Carmen G Kalbermatter, Maarij Khan, Anna M Schläfli, Rina Mehmeti, Mario P Tschan

Eur J Histochem· January 2025

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HSPA8 Chaperone Complex Drives Chaperone-Mediated Autophagy Regulation in Acute Promyelocytic Leukemia Cell Differentiation.
Sreoshee Rafiq, Irene Mungure, Yara Banz, Nicolas J Niklaus, Thomas Kaufmann, Mario P Tschan

Pharmacology· July 2024

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Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach.
Harpreet K Mandhair, Ramin Radpour, Mira Westerhuis, Yara Banz, Magali Humbert, Mario P Tschan

Leukemia· February 2024

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Isoform-specific, Semi-quantitative Determination of Highly Homologous Protein Levels via CRISPR-Cas9-mediated HiBiT Tagging.
Kristina Seiler, Sreoshee Rafiq, Mario P Tschan

Bio Protoc· July 2023

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Immunohistochemical Detection of the Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Formalin-Fixed and Paraffin-Embedded Tissues.
Tereza Losmanová, Mario P Tschan, José A Galván, Sabina Berezowska

Methods Mol Biol· September 2022

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TBK1 is part of a galectin 8 dependent membrane damage recognition complex and drives autophagy upon Adenovirus endosomal escape.
Noémie Pied, Coralie F Daussy, Zoé Denis, Jessica Ragues, Muriel Faure, Mario P Tschan

PLoS Pathog· July 2022

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Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions.
Kristina Seiler, Magali Humbert, Petra Minder, Iris Mashimo, Anna M Schläfli, Mario P Tschan

Cell Death Dis· May 2022

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Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia.
Maurizio Gianni', Laura Goracci, Anna Schlaefli, Alessandra Di Veroli, Mami Kurosaki, Mario P Tschan

Cell Death Dis· January 2022

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Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung".
Tereza Losmanová, Félice A Janser, Magali Humbert, Igor Tokarchuk, Anna M Schläfli, Mario P Tschan

Oxid Med Cell Longev· November 2021

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Lysosomes in acute myeloid leukemia: potential therapeutic targets?
Sreoshee Rafiq, Sharon L McKenna, Sylviane Muller, Mario P Tschan, Magali Humbert

Leukemia· October 2021

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Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy.
Tereza Losmanova, Philipp Zens, Amina Scherz, Ralph A Schmid, Mario P Tschan

Cells· October 2021

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Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability.
Igor Tokarchuk, Félice A Janser, Anna M Schläfli, Marta Teixeira Pinto, Magali Humbert, Mario P Tschan

Biochem Biophys Res Commun· September 2021

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Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer.
Zhang Yang, Shun-Qing Liang, Maria Saliakoura, Haitang Yang, Eric Vassella, Mario Tschan

EMBO Mol Med· September 2021

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Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy.
Magali Humbert, Kristina Seiler, Severin Mosimann, Vreni Rentsch, Katyayani Sharma, Mario P Tschan

Cell Death Differ· August 2021

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The Multifaceted Functions of Autophagy in Breast Cancer Development and Treatment.
Nicolas J Niklaus, Igor Tokarchuk, Mara Zbinden, Anna M Schläfli, Paola Maycotte, Mario P Tschan

Cells· June 2021

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Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung.
Tereza Losmanová, Félice A Janser, Magali Humbert, Igor Tokarchuk, Anna M Schläfli, Mario P Tschan

Oxid Med Cell Longev· May 2021

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ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells.
Anna M Schläfli, Igor Tokarchuk, Sarah Parejo, Susanne Jutzi, Sabina Berezowska, Mario P Tschan

Sci Rep· April 2021

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Autophagy and coronavirus infection - a Trojan horse or Achilles heel?
Kristina Seiler, Mario P P Tschan

Swiss Med Wkly· January 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Daniel Patschan, Mario P Tschan

Autophagy· January 2021

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The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer.
Noëlle Dommann, Daniel Sánchez-Taltavull, Linda Eggs, Fabienne Birrer, Tess Brodie, Mario P Tschan

Cancers (Basel)· July 2020

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Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells.
Nina Orfali, Deborah Shan-Krauer, Tracey R O'Donovan, Nigel P Mongan, Lorraine J Gudas, Mario P Tschan

Mol Oncol· June 2020

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Progress and Challenges in The Use of MAP1LC3 as a Legitimate Marker for Measuring Dynamic Autophagy In Vivo.
Srinivasa Reddy Bonam, Jagadeesh Bayry, Mario P Tschan, Sylviane Muller

Cells· May 2020

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Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot.
Magali Humbert, María Morán, Patricia de la Cruz-Ojeda, Jordi Muntané, Tabea Wiedmer, Mario P Tschan

Biology (Basel)· March 2020

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