Publications by authors named "Marion Dickson"

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Effects of a topical treatment with spleen tyrosine kinase inhibitor in healthy subjects and patients with cold urticaria or chronic spontaneous urticaria: Results of a phase 1a/b randomised double-blind placebo-controlled study.
Marion C Dickson, Alexandra Walker, Clive Grattan, Hayley Perry, Nicola Williams

Br J Clin Pharmacol· December 2021

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Safety, pharmacokinetics and pharmacodynamics of a topical SYK inhibitor in cutaneous lupus erythematosus: A double-blind Phase Ib study.
Alex Walker, Lars Erwig, Katie Foster, Katherine Nevin, Joerg Wenzel, Marion Dickson

Exp Dermatol· November 2021

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GSK2646264, a spleen tyrosine kinase inhibitor, attenuates the release of histamine in ex vivo human skin.
Cesar Ramirez Molina, Sidsel Falkencrone, Per S Skov, Edward Hooper-Greenhill, Mike Barker, Marion C Dickson

Br J Pharmacol· April 2019

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Discovery of potent and selective Spleen Tyrosine Kinase inhibitors for the topical treatment of inflammatory skin disease.
Michael D Barker, John Liddle, Francis L Atkinson, David Matthew Wilson, Marion C Dickson

Bioorg Med Chem Lett· November 2018

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Highly selective SYK inhibitor, GSK143, abrogates survival signals in chronic lymphocytic leukaemia.
Abraham M Varghese, Andy Rawstron, Darren Newton, Reuben M Tooze, Talha Munir, Marion Dickson

Br J Haematol· September 2018

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Spleen tyrosine kinase (SYK) is a potential target for the treatment of cutaneous lupus erythematosus patients.
Christine Braegelmann, Michael Hölzel, Valerie Ludbrook, Marion Dickson, Nil Turan

Exp Dermatol· May 2016

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A model of skin inflammation in humans leads to a rapid and reproducible increase in the interferon response signature: a potential translational model for drug development.
Marion C Dickson, Valerie J Ludbrook, Hayley C Perry, Paul A Wilson, Sam J Garthside

Inflamm Res· April 2015

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Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor.
John Liddle, Francis L Atkinson, Michael D Barker, Paul S Carter, Neil R Curtis, Marion C Dickson

Bioorg Med Chem Lett· October 2011

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Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci.
Charlotte Vignal, Aruna T Bansal, David J Balding, Michael H Binks, Marion C Dickson

Arthritis Rheum· January 2009

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Potential novel biomarkers of disease activity in rheumatoid arthritis patients: CXCL13, CCL23, transforming growth factor alpha, tumor necrosis factor receptor superfamily member 9, and macrophage colony-stimulating factor.
Inmaculada Rioja, Fiona J Hughes, Catriona H Sharp, Linda C Warnock, Doug S Montgomery, Marion C Dickson

Arthritis Rheum· August 2008

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The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritis.
Ioanna Marinou, Douglas S Montgomery, Marion C Dickson, Michael H Binks, David J Moore

Arthritis Res Ther· November 2007

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Independent associations of anti-cyclic citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis.
Devesh Mewar, Annabel Coote, David J Moore, Ioanna Marinou, Jodie Keyworth, Marion C Dickson

Arthritis Res Ther· February 2007

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5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase.
Paul Bamborough, John A Christopher, Geoffrey J Cutler, Marion C Dickson, Geoffrey W Mellor

Bioorg Med Chem Lett· December 2006

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IkappaB kinase epsilon interacts with p52 and promotes transactivation via p65.
Claudia Wietek, Catherine S Cleaver, Valerie Ludbrook, Jonathan Wilde, Julia White, Marion Dickson

J Biol Chem· November 2006

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Gene expression profiles in the rat streptococcal cell wall-induced arthritis model identified using microarray analysis.
Inmaculada Rioja, Chris L Clayton, Simon J Graham, Paul F Life, Marion C Dickson

Arthritis Res Ther· March 2006

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Fluid Shear Stress Modulation of Gene Expression in Endothelial Cells.
Martin Braddock, Jean-Luc Schwachtgen, Parul Houston, Marion C. Dickson, Michael J. Lee

News Physiol Sci· October 1998

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