Publications by authors named "Mark A Dewitt"

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High-level correction of the sickle mutation is amplified during erythroid differentiation.
Wendy Magis, Mark A DeWitt, Stacia K Wyman, Jonathan T Vu, Seok-Jin Heo

iScience· June 2022

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Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Nithin Sam Ravi, Beeke Wienert, Stacia K Wyman, Henry William Bell, Anila George, Mark A DeWitt

Elife· February 2022

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Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells.
Jiyung J Shin, Markus S Schröder, Francisco Caiado, Stacia K Wyman, Nicolas L Bray, Mark A Dewitt

Cell Rep· September 2020

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ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin.
Mandy Y Boontanrart, Markus S Schröder, Gautier M Stehli, Marija Banović, Stacia K Wyman, Mark A DeWitt

Cell Rep· August 2020

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CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells.
Jennifer E Chung, Wendy Magis, Jonathan Vu, Seok-Jin Heo, Kirmo Wartiovaara, Mark A DeWitt

PLoS One· September 2019

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Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair.
Anastasia Lomova, Danielle N Clark, Beatriz Campo-Fernandez, Carmen Flores-Bjurström, Michael L Kaufman, Mark A DeWitt

Stem Cells· February 2019

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Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA induces homology-directed DNA repair.
Kunwoo Lee, Michael Conboy, Hyo Min Park, Fuguo Jiang, Hyun Jin Kim, Mark A Dewitt

Nat Biomed Eng· October 2017

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Covalent Protein Labeling and Improved Single-Molecule Optical Properties of Aqueous CdSe/CdS Quantum Dots.
Sara M Wichner, Victor R Mann, Alexander S Powers, Maya A Segal, Mustafa Mir, Mark A DeWitt

ACS Nano· July 2017

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Genome editing via delivery of Cas9 ribonucleoprotein.
Mark A DeWitt, Jacob E Corn, Dana Carroll

Methods· May 2017

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Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering.
Kunwoo Lee, Vanessa A Mackley, Anirudh Rao, Anthony T Chong, Mark A Dewitt

Elife· May 2017

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Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells.
Mark A DeWitt, Wendy Magis, Nicolas L Bray, Tianjiao Wang, Jennifer R Berman

Sci Transl Med· October 2016

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Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA.
Christopher D Richardson, Graham J Ray, Mark A DeWitt, Gemma L Curie, Jacob E Corn

Nat Biotechnol· March 2016

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The AAA3 domain of cytoplasmic dynein acts as a switch to facilitate microtubule release.
Mark A DeWitt, Caroline A Cypranowska, Frank B Cleary, Vladislav Belyy, Ahmet Yildiz

Nat Struct Mol Biol· January 2015

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Tension on the linker gates the ATP-dependent release of dynein from microtubules.
Frank B Cleary, Mark A Dewitt, Thomas Bilyard, Zaw Min Htet, Vladislav Belyy

Nat Commun· August 2014

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Bidirectional helical motility of cytoplasmic dynein around microtubules.
Sinan Can, Mark A Dewitt, Ahmet Yildiz

Elife· July 2014

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Cytoplasmic dynein moves through uncoordinated stepping of the AAA+ ring domains.
Mark A DeWitt, Amy Y Chang, Peter A Combs, Ahmet Yildiz

Science· January 2012

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Distance mapping in proteins using fluorescence spectroscopy: the tryptophan-induced quenching (TrIQ) method.
Steven E Mansoor, Mark A Dewitt, David L Farrens

Biochemistry· November 2010

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The conformations of the manganese transport regulator of Bacillus subtilis in its metal-free state.
Mark A DeWitt, Joseph I Kliegman, John D Helmann, Richard G Brennan, David L Farrens

J Mol Biol· February 2007

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