Publications by authors named "Mark A Gregory"

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Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation.
Hae J Park, Mark A Gregory, Vadym Zaberezhnyy, Andrew Goodspeed, Craig T Jordan

Elife· October 2022

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Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.
Mark A Gregory, Travis Nemkov, Hae J Park, Vadym Zaberezhnyy, Sarah Gehrke

Clin Cancer Res· July 2019

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Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia.
Mark A Gregory, Travis Nemkov, Julie A Reisz, Vadym Zaberezhnyy, Kirk C Hansen

Exp Hematol· February 2018

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ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.
Mark A Gregory, Angelo D'Alessandro, Francesca Alvarez-Calderon, Jihye Kim, Travis Nemkov

Proc Natl Acad Sci U S A· October 2016

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Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations.
Francesca Alvarez-Calderon, Mark A Gregory, Catherine Pham-Danis, Deborah DeRyckere, Brett M Stevens

Clin Cancer Res· March 2015

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Distributed efficient similarity search mechanism in wireless sensor networks.
Khandakar Ahmed, Mark A Gregory

Sensors (Basel)· March 2015

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Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1(+) leukemia.
Lori A Gardner, Jelena Klawitter, Mark A Gregory, Vadym Zaberezhnyy, Dmitry Baturin

Am J Hematol· September 2014

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Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.
Anna Spreafico, John J Tentler, Todd M Pitts, Aik Choon Tan, Mark A Gregory

Clin Cancer Res· August 2013

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Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer.
Shanna K Nifoussi, Julie A Vrana, Aaron M Domina, Alfredo De Biasio, Jingang Gui, Mark A Gregory

PLoS One· May 2013

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Using functional genomics to overcome therapeutic resistance in hematological malignancies.
Francesca Alvarez-Calderon, Mark A Gregory, James DeGregori

Immunol Res· March 2013

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Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity.
Qin Zhang, Erick Spears, David N Boone, Zhaoliang Li, Mark A Gregory

Proc Natl Acad Sci U S A· January 2013

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Wnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl.
Mark A Gregory, Tzu L Phang, Paolo Neviani, Francesca Alvarez-Calderon, Christopher A Eide

Cancer Cell· July 2010

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The ARF tumor suppressor: keeping Myc on a leash.
Mark A Gregory, Ying Qi, Stephen R Hann

Cell Cycle· February 2005

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p19ARF directly and differentially controls the functions of c-Myc independently of p53.
Ying Qi, Mark A Gregory, Zhaoliang Li, Jeffrey P Brousal, Kimberly West

Nature· October 2004

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MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol.
Aaron M Domina, Julie A Vrana, Mark A Gregory, Stephen R Hann, Ruth W Craig

Oncogene· July 2004

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Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization.
Mark A Gregory, Ying Qi, Stephen R Hann

J Biol Chem· December 2003

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