Publications by authors named "Mark A Kluth"

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Dimethyl sulfoxide in cryopreserved mesenchymal stromal cell therapy products: is there a safety risk to patients?
Elke Niebergall-Roth, Mark Andreas Kluth

J Transl Med· August 2025

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Systemic treatment of recessive dystrophic epidermolysis bullosa with mesenchymal stromal cells: a scoping review of the literature and conclusions for future clinical research.
Elke Niebergall-Roth, Kathrin Dieter, Markus H Frank, Mark A Kluth

J Dermatolog Treat· December 2024

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Anti-Inflammatory and Anti-(Lymph)angiogenic Properties of an ABCB5+ Limbal Mesenchymal Stem Cell Population.
Berbang Meshko, Thomas L A Volatier, Johanna Mann, Mark A Kluth, Christoph Ganss

Int J Mol Sci· September 2024

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Potency assay to predict the anti-inflammatory capacity of a cell therapy product for macrophage-driven diseases: overcoming the challenges of assay development and validation.
Samar Sadeghi, Laura Nimtz, Elke Niebergall-Roth, Alexandra Norrick, Stefan Hägele, Mark Andreas Kluth

Cytotherapy· May 2024

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Clinical-grade human skin-derived ABCB5+ mesenchymal stromal cells exert anti-apoptotic and anti-inflammatory effects and modulate mRNA expression in a cisplatin-induced kidney injury murine model.
Erika Rendra, Adriana Torres Crigna, Cristina Daniele, Carsten Sticht, Maike Cueppers, Mark Andreas Kluth

Front Immunol· January 2024

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Adipose-Derived Mesenchymal Stem Cells Protect Endothelial Cells from Hypoxic Injury by Suppressing Terminal UPR In Vivo and In Vitro.
Michael Keese, Jiaxing Zheng, Kaixuan Yan, Karen Bieback, Benito A Yard, Mark Andreas Kluth

Int J Mol Sci· December 2023

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Corrigendum to ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa [Cytotherapy 25 (2023) 782-788/1562].
Kathrin Dieter, Elke Niebergall-Roth, Cristina Daniele, Silvia Fluhr, Natasha Y Frank, Mark A Kluth

Cytotherapy· September 2023

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ABCB5 mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa.
Kathrin Dieter, Elke Niebergall-Roth, Cristina Daniele, Silvia Fluhr, Natasha Y Frank, Mark A Kluth

Cytotherapy· July 2023

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Drug Regulatory-Compliant Validation of a qPCR Assay for Bioanalysis Studies of a Cell Therapy Product with a Special Focus on Matrix Interferences in a Wide Range of Organ Tissues.
Hannes M Schröder, Elke Niebergall-Roth, Alexandra Norrick, Jasmina Esterlechner, Christoph Ganss, Mark A Kluth

Cells· July 2023

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ABCB5+ Limbal Epithelial Stem Cells Inhibit Developmental but Promote Inflammatory (Lymph) Angiogenesis While Preventing Corneal Inflammation.
Berbang Meshko, Thomas L A Volatier, Karina Hadrian, Shuya Deng, Yanhong Hou, Mark Andreas Kluth

Cells· June 2023

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Kinetics of Wound Development and Healing Suggests a Skin-Stabilizing Effect of Allogeneic ABCB5 Mesenchymal Stromal Cell Treatment in Recessive Dystrophic Epidermolysis Bullosa.
Elke Niebergall-Roth, Kathrin Dieter, Cristina Daniele, Silvia Fluhr, Maria Khokhrina, Mark A Kluth

Cells· May 2023

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ABCB5 mesenchymal stromal cells therapy protects from hypoxia by restoring Ca homeostasis in vitro and in vivo.
Kaixuan Yan, Jiaxing Zheng, Mark Andreas Kluth, Lin Li, Christoph Ganss

Stem Cell Res Ther· February 2023

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Skin-Derived ABCB5 Mesenchymal Stem Cells for High-Medical-Need Inflammatory Diseases: From Discovery to Entering Clinical Routine.
Elke Niebergall-Roth, Natasha Y Frank, Christoph Ganss, Markus H Frank, Mark A Kluth

Int J Mol Sci· December 2022

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Translational development of ABCB5 dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers.
Andreas Kerstan, Kathrin Dieter, Elke Niebergall-Roth, Sabrina Klingele, Michael Jünger, Mark A Kluth

Stem Cell Res Ther· September 2022

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Angiogenin Released from ABCB5 Stromal Precursors Improves Healing of Diabetic Wounds by Promoting Angiogenesis.
Karmveer Singh, Pallab Maity, Albert Kallon Koroma, Abhijit Basu, Rajeev Kumar Pandey, Mark A Kluth

J Invest Dermatol· June 2022

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Potential Therapeutic Effects of Long-Term Stem Cell Administration: Impact on the Gene Profile and Kidney Function of PKD/Mhm (Cy/+) Rats.
Daniela Nardozi, Stefania Palumbo, Arif Ul Maula Khan, Carsten Sticht, Karen Bieback, Mark Andreas Kluth

J Clin Med· May 2022

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Allogeneic ABCB5 mesenchymal stem cells for treatment-refractory chronic venous ulcers: a phase I/IIa clinical trial.
Andreas Kerstan, Kathrin Dieter, Elke Niebergall-Roth, Ann-Kathrin Dachtler, Korinna Kraft, Mark A Kluth

JID Innov· January 2022

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Clinical trial of ABCB5+ mesenchymal stem cells for recessive dystrophic epidermolysis bullosa.
Dimitra Kiritsi, Kathrin Dieter, Elke Niebergall-Roth, Silvia Fluhr, Cristina Daniele, Mark A Kluth

JCI Insight· November 2021

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ABCB5+ dermal mesenchymal stromal cells with favorable skin homing and local immunomodulation for recessive dystrophic epidermolysis bullosa treatment.
Julia Riedl, Michael Pickett-Leonard, Cindy Eide, Mark Andreas Kluth, Christoph Ganss

Stem Cells· July 2021

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Process development and safety evaluation of ABCB5 limbal stem cells as advanced-therapy medicinal product to treat limbal stem cell deficiency.
Alexandra Norrick, Jasmina Esterlechner, Elke Niebergall-Roth, Ulf Dehio, Samar Sadeghi, Mark A Kluth

Stem Cell Res Ther· March 2021

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Ex vivo-expanded highly pure ABCB5 mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data.
Andreas Kerstan, Elke Niebergall-Roth, Jasmina Esterlechner, Hannes M Schröder, Martin Gasser, Mark A Kluth

Cytotherapy· February 2021

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Process data of allogeneic ex vivo-expanded ABCB5 mesenchymal stromal cells for human use: off-the-shelf GMP-manufactured donor-independent ATMP.
Seda Ballikaya, Samar Sadeghi, Elke Niebergall-Roth, Laura Nimtz, Jens Frindert, Mark A Kluth

Stem Cell Res Ther· November 2020

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Correction to: Human skin-derived ABCB5 stem cell injection improves liver disease parameters in Mdr2KO mice.
Vanessa Hartwig, Bedair Dewidar, Tao Lin, Anne Dropmann, Christoph Ganss, Mark Andreas Kluth

Arch Toxicol· December 2019

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Human skin-derived ABCB5 stem cell injection improves liver disease parameters in Mdr2KO mice.
Vanessa Hartwig, Bedair Dewidar, Tao Lin, Anne Dropmann, Christoph Ganss, Mark Andreas Kluth

Arch Toxicol· September 2019

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Newly Defined ATP-Binding Cassette Subfamily B Member 5 Positive Dermal Mesenchymal Stem Cells Promote Healing of Chronic Iron-Overload Wounds via Secretion of Interleukin-1 Receptor Antagonist.
Seppe Vander Beken, Juliane C de Vries, Barbara Meier-Schiesser, Patrick Meyer, Dongsheng Jiang, Mark A Kluth

Stem Cells· August 2019

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