Publications by authors named "Mark A Miles"

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TLR7 deficiency enhances inflammation in the URT but reduces LRT immunity following influenza A infection.
Mark A Miles, Sahan Jayawardena, Stella Liong, Felicia Liong, Gemma S Trollope

Sci Rep· May 2025

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Exploring the Contribution of TLR7 to Sex-Based Disparities in Respiratory Syncytial Virus (RSV)-Induced Inflammation and Immunity.
Mark A Miles, Thomas D Huttmann, Stella Liong, Felicia Liong, John J O'Leary

Viruses· March 2025

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Metabolic reprogramming, malignant transformation and metastasis: Lessons from chronic lymphocytic leukaemia and prostate cancer.
Madison T Hindes, Anthony M McElligott, Oliver G Best, Mark P Ward, Stavros Selemidis, Mark A Miles

Cancer Lett· January 2025

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TLR7 Promotes Acute Inflammatory-Driven Lung Dysfunction in Influenza-Infected Mice but Prevents Late Airway Hyperresponsiveness.
Mark A Miles, Stella Liong, Felicia Liong, Gemma S Trollope, Hao Wang

Int J Mol Sci· December 2024

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Components of the Endosome-Lysosome Vesicular Machinery as Drivers of the Metastatic Cascade in Prostate Cancer.
Bukuru Dieu-Donne Nturubika, Jessica Logan, Ian R D Johnson, Courtney Moore, Ka Lok Li, Mark A Miles

Cancers (Basel)· December 2024

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Gestational influenza A virus infection elicits nonresolving vascular dysfunction and T-cell accumulation in the aorta of mice.
Osezua Oseghale, Kylie M Quinn, Madison Coward-Smith, Felicia Liong, Mark A Miles

Am J Physiol Heart Circ Physiol· October 2024

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Early-Life Respiratory Syncytial Virus (RSV) Infection Triggers Immunological Changes in Gut-Associated Lymphoid Tissues in a Sex-Dependent Manner in Adulthood.
Stella Liong, Felicia Liong, Mitra Mohsenipour, Elisa L Hill-Yardin, Mark A Miles

Cells· October 2024

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Brain region-specific alterations in gene expression trajectories in the offspring born from influenza A virus infected mice.
Stella Liong, K H Christopher Choy, Simone N De Luca, Felicia Liong, Madison Coward-Smith, Mark A Miles

Brain Behav Immun· August 2024

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Low dose aspirin prevents endothelial dysfunction in the aorta and foetal loss in pregnant mice infected with influenza A virus.
Madison Coward-Smith, Stella Liong, Osezua Oseghale, Jonathan R Erlich, Mark A Miles

Front Immunol· April 2024

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TLR9 Monotherapy in Immune-Competent Mice Suppresses Orthotopic Prostate Tumor Development.
Mark A Miles, Raymond Luong, Eunice E To, Jonathan R Erlich, Stella Liong

Cells· January 2024

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TLR7 promotes chronic airway disease in RSV-infected mice.
Mark A Miles, Stella Liong, Felicia Liong, Madison Coward-Smith, Gemma S Trollope

Front Immunol· October 2023

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Influenza A virus infection during pregnancy causes immunological changes in gut-associated lymphoid tissues of offspring mice.
Stella Liong, Mark A Miles, Mitra Mohsenipour, Felicia Liong, Elisa L Hill-Yardin

Am J Physiol Gastrointest Liver Physiol· September 2023

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Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Adam H Tencer, Yucong Yu, Sebastien Z Causse, Grant R Campbell, Brianna J Klein, Mark A Miles

Nat Struct Mol Biol· September 2023

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Glycolysis and the Pentose Phosphate Pathway Promote LPS-Induced NOX2 Oxidase- and IFN-β-Dependent Inflammation in Macrophages.
Jonathan R Erlich, Eunice E To, Raymond Luong, Felicia Liong, Stella Liong, Mark A Miles

Antioxidants (Basel)· July 2022

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Therapeutic Targeting of Endosome and Mitochondrial Reactive Oxygen Species Protects Mice From Influenza Virus Morbidity.
Eunice E To, Jonathan R Erlich, Felicia Liong, Stella Liong, Raymond Luong, Mark A Miles

Front Pharmacol· March 2022

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The smac mimetic LCL161 targets established pulmonary osteosarcoma metastases in mice.
Michael A Harris, Tanmay M Shekhar, Mark A Miles, Carmelo Cerra, Christine J Hawkins

Clin Exp Metastasis· October 2021

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Mutagenic Consequences of Sublethal Cell Death Signaling.
Christine J Hawkins, Mark A Miles

Int J Mol Sci· June 2021

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Transient NK Cell Depletion Facilitates Pulmonary Osteosarcoma Metastases After Intravenous Inoculation in Athymic Mice.
Michael A Harris, BBioMed Hons, Tanmay M Shekhar, Lucy A Coupland, Mark A Miles

J Adolesc Young Adult Oncol· December 2020

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Smac mimetics can provoke lytic cell death that is neither apoptotic nor necroptotic.
Mark A Miles, Sarah Caruso, Amy A Baxter, Ivan K H Poon, Christine J Hawkins

Apoptosis· August 2020

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In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations.
Mark A Miles, Christine J Hawkins

Cell Death Dis· August 2020

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Tetrazolium reduction assays under-report cell death provoked by clinically relevant concentrations of proteasome inhibitors.
Michael A Harris, Christine J Hawkins, Mark A Miles

Mol Biol Rep· June 2020

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The Proteasome Inhibitor Ixazomib Inhibits the Formation and Growth of Pulmonary and Abdominal Osteosarcoma Metastases in Mice.
Michael A Harris, Mark A Miles, Tanmay M Shekhar, Carmelo Cerra, Smitha R Georgy

Cancers (Basel)· May 2020

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Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly.
Georgia K Atkin-Smith, Mark A Miles, Rochelle Tixeira, Fung T Lay, Mubing Duan

Cell Rep· November 2019

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Proteasome inhibitors trigger mutations via activation of caspases and CAD, but mutagenesis provoked by the HDAC inhibitors vorinostat and romidepsin is caspase/CAD-independent.
Mark A Miles, Michael A Harris, Christine J Hawkins

Apoptosis· June 2019

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CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants.
David T Bloomer, Tanja Kitevska-Ilioski, Delara Pantaki-Eimany, Yanhao Ji, Mark A Miles

Biochem J· May 2019

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