Publications by authors named "Mark A Mintun"

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Posttreatment Amyloid Levels and Clinical Outcomes Following Donanemab for Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ 2 Randomized Clinical Trial.
Ming Lu, Min Jung Kim, Emily C Collins, Sergey Shcherbinin, Amy K Ellinwood, Mark A Mintun

JAMA Neurol· December 2025

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Donanemab in early symptomatic Alzheimer's disease: results from the TRAILBLAZER-ALZ 2 long-term extension.
Jennifer A Zimmer, John R Sims, Cynthia D Evans, Emel Serap Monkul Nery, Hong Wang, Mark A Mintun

J Prev Alzheimers Dis· December 2025

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Alzheimer's Imaging Consortium.
Chris Conklin, Stefan Radonjic, David Scott, Madhura Ingalhalikar, Luc Bracoud, Mark A Mintun

Alzheimers Dement· December 2025

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Alzheimer's Imaging Consortium.
Ian A Kennedy, Min Jung Kim, Ming Lu, John R Sims, Mark A Mintun

Alzheimers Dement· December 2025

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Alzheimer's Imaging Consortium.
Alexis Moscoso, Antoine Leuzy, Lars Lau Raket, Victor L Villemagne, Gregory Klein, Mark A Mintun

Alzheimers Dement· December 2025

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The effect of modified donanemab titration on amyloid-related imaging abnormalities with edema/effusions and amyloid reduction: 18-month results from TRAILBLAZER-ALZ 6.
Hong Wang, Emel Serap Monkul Nery, Paul Ardayfio, Rashna Khanna, Diana Otero Svaldi, Mark A Mintun

J Prev Alzheimers Dis· September 2025

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Dynamic proportional loss of functional connectivity revealed change of left superior frontal gyrus in subjective cognitive decline: an explanatory study based on Chinese and Western cohorts.
Luyao Wang, Wenjing Hu, Fan Dong, Can Sheng, Jinglong Wu, Mark A Mintun

Geroscience· August 2025

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Analytical Validation and Performance of a Blood-Based P-tau217 Diagnostic Test for Alzheimer Disease.
Adam Abel, Antonio Chambers, Jeff Fill, Heinz Reiske, Ming Lu, Mark A Mintun

J Appl Lab Med· May 2025

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Modified titration of donanemab reduces ARIA risk and maintains amyloid reduction.
Hong Wang, Emel Serap Monkul Nery, Paul Ardayfio, Rashna Khanna, Diana Otero Svaldi, Mark A Mintun

Alzheimers Dement· April 2025

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Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model.
Antoine Leuzy, Lars Lau Raket, Victor L Villemagne, Gregory Klein, Matteo Tonietto, Mark A Mintun

Alzheimers Dement· September 2024

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APOE ε4's impact on response to amyloid therapies in early symptomatic Alzheimer's disease: Analyses from multiple clinical trials.
Cynthia D Evans, JonDavid Sparks, Scott W Andersen, Dawn A Brooks, Paula M Hauck, Mark A Mintun

Alzheimers Dement· December 2023

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Tau as a diagnostic instrument in clinical trials to predict amyloid in Alzheimer's disease.
Sergey Shcherbinin, Amanda Morris, Ixavier A Higgins, Ilke Tunali, Ming Lu, Mark A Mintun

Alzheimers Dement (N Y)· August 2023

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Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression.
Vikas Kotari, Sudeepti Southekal, Michael Navitsky, Ian A Kennedy, Ming Lu, Mark A Mintun

Alzheimers Res Ther· February 2023

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Association of Donanemab Treatment With Exploratory Plasma Biomarkers in Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ Randomized Clinical Trial.
Michael J Pontecorvo, Ming Lu, Samantha C Burnham, Andrew E Schade, Jeffrey L Dage, Mark A Mintun

JAMA Neurol· December 2022

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Association of Amyloid Reduction After Donanemab Treatment With Tau Pathology and Clinical Outcomes: The TRAILBLAZER-ALZ Randomized Clinical Trial.
Sergey Shcherbinin, Cynthia D Evans, Ming Lu, Scott W Andersen, Michael J Pontecorvo, Mark A Mintun

JAMA Neurol· October 2022

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Baseline Microglial Activation Correlates With Brain Amyloidosis and Longitudinal Cognitive Decline in Alzheimer Disease.
Qing Wang, Gengsheng Chen, Suzanne E Schindler, Jon Christensen, Nicole S McKay, Mark A Mintun

Neurol Neuroimmunol Neuroinflamm· May 2022

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Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
Willemijn J Jansen, Olin Janssen, Betty M Tijms, Stephanie J B Vos, Rik Ossenkoppele, Mark A Mintun

JAMA Neurol· March 2022

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Relationships Between Cognition and Neuropathological Tau in Alzheimer's Disease Assessed by 18F Flortaucipir PET.
Michael D Devous, Adam S Fleisher, Michael J Pontecorvo, Ming Lu, Andrew Siderowf, Mark A Mintun

J Alzheimers Dis· September 2021

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Clinicopathological Correlation: Dopamine and Amyloid PET Imaging with Neuropathology in Three Subjects Clinically Diagnosed with Alzheimer's Disease or Dementia with Lewy Bodies.
Harsh V Gupta, Thomas G Beach, Shyamal H Mehta, Holly A Shill, Erika Driver-Dunckley, Mark A Mintun

J Alzheimers Dis· September 2021

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Donanemab in Early Alzheimer's Disease. Reply.
Mark A Mintun, Alette M Wessels, John R Sims

N Engl J Med· August 2021

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A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease.
Stephen Salloway, Martin Farlow, Eric McDade, David B Clifford, Guoqiao Wang, Mark A Mintun

Nat Med· July 2021

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Donanemab in Early Alzheimer's Disease.
Mark A Mintun, Albert C Lo, Cynthia Duggan Evans, Alette M Wessels, Paul A Ardayfio

N Engl J Med· May 2021

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Aggregated Tau Measured by Visual Interpretation of Flortaucipir Positron Emission Tomography and the Associated Risk of Clinical Progression of Mild Cognitive Impairment and Alzheimer Disease: Results From 2 Phase III Clinical Trials.
Ming Lu, Michael J Pontecorvo, Michael D Devous, Anupa K Arora, Nicholas Galante, Mark A Mintun

JAMA Neurol· April 2021

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Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes.
Adam S Fleisher, Michael J Pontecorvo, Michael D Devous, Ming Lu, Anupa K Arora, Mark A Mintun

JAMA Neurol· July 2020

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Comparison of regional flortaucipir PET with quantitative tau immunohistochemistry in three subjects with Alzheimer's disease pathology: a clinicopathological study.
Michael J Pontecorvo, C Dirk Keene, Thomas G Beach, Thomas J Montine, Anupa K Arora, Mark A Mintun

EJNMMI Res· June 2020

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