Publications by authors named "Mark Cartwright"

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De Novo Design of Miniprotein Inhibitors of Bacterial Adhesins.
Adam Chazin-Gray, Tuscan Thompson, Edward Lopatto, Pearl Magala, Patrick Erickson, Mark Cartwright

Res Sq· November 2025

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Design of Miniprotein Inhibitors of Bacterial Adhesins.
Adam M Chazin-Gray, Tuscan R Thompson, Edward D B Lopatto, Pearl Magala, Patrick W Erickson, Mark J Cartwright

bioRxiv· August 2025

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Individual identification in acoustic recordings.
Elly Knight, Tessa Rhinehart, Devin R de Zwaan, Matthew J Weldy, Mark Cartwright

Trends Ecol Evol· October 2024

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Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279.
Silvana Leit, Jeremy Greenwood, Samantha Carriero, Sayan Mondal, Robert Abel, Mark Cartwright

J Med Chem· August 2023

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Danicopan, an Oral Complement Factor D Inhibitor, Exhibits High and Sustained Exposure in Ocular Tissues in Preclinical Studies.
David D Boyer, Ya-Ping Ko, Steven D Podos, Mark E Cartwright, Xiang Gao

Transl Vis Sci Technol· October 2022

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Enhancers of Host Immune Tolerance to Bacterial Infection Discovered Using Linked Computational and Experimental Approaches.
Megan M Sperry, Richard Novak, Vishal Keshari, Alexandre L M Dinis, Mark J Cartwright

Adv Sci (Weinh)· September 2022

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Modeling pulmonary cystic fibrosis in a human lung airway-on-a-chip.
Roberto Plebani, Ratnakar Potla, Mercy Soong, Haiqing Bai, Zohreh Izadifar, Mark J Cartwright

J Cyst Fibros· July 2022

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Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock.
Michael Super, Edward J Doherty, Mark J Cartwright, Benjamin T Seiler, Fernanda Langellotto

Nat Biomed Eng· January 2022

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A Modular Biomaterial Scaffold-Based Vaccine Elicits Durable Adaptive Immunity to Subunit SARS-CoV-2 Antigens.
Fernanda Langellotto, Maxence O Dellacherie, Chyenne Yeager, Hamza Ijaz, Jingyou Yu, Mark J Cartwright

Adv Healthc Mater· November 2021

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Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection.
Francesca S Gazzaniga, Diogo M Camacho, Meng Wu, Matheus F Silva Palazzo, Alexandre L M Dinis, Mark J Cartwright

Front Cell Infect Microbiol· July 2021

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Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment.
Benjamin T Seiler, Mark Cartwright, Alexandre L M Dinis, Shannon Duffy, Patrick Lombardo, David Cartwright

F1000Res· June 2020

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Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites.
Alessio Tovaglieri, Alexandra Sontheimer-Phelps, Annelies Geirnaert, Rachelle Prantil-Baun, Diogo M Camacho, Mark J Cartwright

Microbiome· March 2019

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Discovery of MK-6169, a Potent Pan-Genotype Hepatitis C Virus NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Substitutions.
Wensheng Yu, Ling Tong, Oleg Selyutin, Lei Chen, Bin Hu, Mark Cartwright

J Med Chem· May 2018

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Analyzing the Potential Root Causes of Variability of Pharmacokinetics in Preclinical Species.
Pierre Daublain, Kung-I Feng, Michael D Altman, Iain Martin, Suman Mukherjee, Mark Cartwright

Mol Pharm· May 2017

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Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms.
Ling Tong, Wensheng Yu, Lei Chen, Oleg Selyutin, Michael P Dwyer, Mark Cartwright

J Med Chem· January 2017

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A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood.
Mark Cartwright, Martin Rottman, Nathan I Shapiro, Benjamin Seiler, Patrick Lombardo, David Cartwright

EBioMedicine· July 2016

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Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor.
Santhosh F Neelamkavil, Sony Agrawal, Thomas Bara, Chad Bennett, Sathesh Bhat, Mark Cartwright

ACS Med Chem Lett· January 2016

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Improved treatment of systemic blood infections using antibiotics with extracorporeal opsonin hemoadsorption.
Tohid F Didar, Mark J Cartwright, Martin Rottman, Amanda R Graveline, Nazita Gamini

Biomaterials· October 2015

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An extracorporeal blood-cleansing device for sepsis therapy.
Joo H Kang, Michael Super, Chong Wing Yung, Ryan M Cooper, Karel Domansky, Mark J Cartwright

Nat Med· October 2014

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Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1).
Yongqi Deng, Zhiwei Yang, Gerald W Shipps, Sie-Mun Lo, Robert West, Mark E Cartwright

Bioorg Med Chem Lett· February 2013

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Progressing preclinical drug candidates: strategies on preclinical safety studies and the quest for adequate exposure.
John Higgins, Mark E Cartwright, Allen C Templeton

Drug Discov Today· August 2012

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Aging, depot origin, and preadipocyte gene expression.
Mark J Cartwright, Karen Schlauch, Marc E Lenburg, Tamara Tchkonia, Tamar Pirtskhalava, Andrew Cartwright

J Gerontol A Biol Sci Med Sci· March 2010

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Exploratory drug safety: a discovery strategy to reduce attrition in development.
Alan S Bass, Mark E Cartwright, Craig Mahon, Richard Morrison, Ronald Snyder

J Pharmacol Toxicol Methods· January 2010

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Phospholipidosis in neurons caused by posaconazole, without evidence for functional neurologic effects.
Mark E Cartwright, Janet Petruska, Joseph Arezzo, Doyle Frank, Mona Litwak

Toxicol Pathol· December 2009

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Increased TNFalpha and CCAAT/enhancer-binding protein homologous protein with aging predispose preadipocytes to resist adipogenesis.
Tamara Tchkonia, Tamar Pirtskhalava, Thomas Thomou, Mark J Cartwright, Barton Wise

Am J Physiol Endocrinol Metab· December 2007

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