Publications by authors named "Mark D Gorrell"

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Development of a Protocol for Long-Term Ex Vivo Normothermic Machine Perfusion of Rodent Livers.
Mark Ly, Daniel Babekuhl, Anita Niu, Paul Yousif, Chuanmin Wang, Mark D Gorrell

Artif Organs· September 2025

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Dipeptidyl peptidase 9 (DPP9) depletion from hepatocytes in experimental primary liver cancer.
JiaLi Carrie Huang, Xinlin Linda Tong, Michelle Sui Wen Xiang, Badwi B Boumelhem, Diarmid P Foulis, Mark D Gorrell

Biochim Biophys Acta Mol Basis Dis· June 2025

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The multifunctional regulatory post-proline protease dipeptidyl peptidase 9 and its inhibitors: new opportunities for therapeutics.
Jasmine Minh Hang Nguyen, Samuel Zolg, Ruth Geiss-Friedlander, Mark Douglas Gorrell

Cell Mol Life Sci· April 2025

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Long-term ex situ normothermic machine perfusion allows regeneration of human livers with severe bile duct injury.
Mark Ly, Ngee-Soon Lau, Claude Dennis, Jinbiao Chen, Charles Risbey, Mark D Gorrell

Am J Transplant· January 2025

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Bile acids mediate fructose-associated liver tumour growth in mice.
Stefan Hargett, Sujoy Lahiri, Greg M Kowalski, Susan Corley, Marin E Nelson, Mark D Gorrell

Biochim Biophys Acta Mol Basis Dis· March 2024

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Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis.
Xin Tracy Liu, Yu Huang, Da Liu, Yingxin Celia Jiang, Min Zhao, Mark Douglas Gorrell

J Transl Med· January 2024

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Application and Diagnostic Performance of Two-Dimensional Shear Wave Elastography and Liver Fibrosis Scores in Adults with Class 3 Obesity.
Ritesh Chimoriya, Vincent Ho, Ziqi Vincent Wang, Ruby Chang, Badwi B Boumelhem, Mark D Gorrell

Nutrients· December 2023

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Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein.
Xin Tracy Liu, Long Hoa Chung, Da Liu, Jinbiao Chen, Yu Huang, Mark D Gorrell

Oncogenesis· November 2022

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Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair.
Oguz Bolgi, Maria Silva-Garcia, Breyan Ross, Esther Pilla, Vijayalakshmi Kari, Mark D Gorrell

EMBO Rep· October 2022

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Targeting CCN2 protects against progressive non-alcoholic steatohepatitis in a preclinical model induced by high-fat feeding and type 2 diabetes.
Jing Ren, Xiaoyu Wang, Sarah N Parry, Christine Yee, Mark D Gorrell

J Cell Commun Signal· September 2022

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DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
Cassandra R Harapas, Kim S Robinson, Kenneth Lay, Jasmine Wong, Ricardo Moreno Traspas, Mark D Gorrell

Sci Immunol· September 2022

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Circulating Dipeptidyl Peptidase Activity Is a Potential Biomarker for Inflammatory Bowel Disease.
Simone E Jaenisch, Catherine A Abbott, Mark D Gorrell, Peter Bampton, Ross N Butler

Clin Transl Gastroenterol· January 2022

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Sitagliptin Is More Effective Than Gliclazide in Preventing  Pro-Fibrotic and Pro-Inflammatory Changes in a Rodent Model of Diet-Induced Non-Alcoholic Fatty Liver Disease.
Jing Ren, Xiaoyu Wang, Christine Yee, Mark D Gorrell, Susan V McLennan

Molecules· January 2022

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Dipeptidyl Peptidase Inhibition Enhances CD8 T Cell Recruitment and Activates Intrahepatic Inflammasome in a Murine Model of Hepatocellular Carcinoma.
James M Henderson, Michelle S W Xiang, Jiali Carrie Huang, Stefanie Wetzel, Linxuan Jiang, Mark D Gorrell

Cancers (Basel)· November 2021

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Differential Effects of 'Vaping' on Lipid and Glucose Profiles and Liver Metabolic Markers in Obese Versus Non-obese Mice.
Hui Chen, Gerard Li, Yik Lung Chan, Hui Emma Zhang, Mark D Gorrell

Front Physiol· November 2021

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An improved production and purification protocol for recombinant soluble human fibroblast activation protein alpha.
Cecy R Xi, Arianna Di Fazio, Naveed Ahmed Nadvi, Michelle Sui Wen Xiang, Hui Emma Zhang, Mark D Gorrell

Protein Expr Purif· May 2021

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DPP9: Comprehensive In Silico Analyses of Loss of Function Gene Variants and Associated Gene Expression Signatures in Human Hepatocellular Carcinoma.
Jiali Carrie Huang, Abdullah Al Emran, Justine Moreno Endaya, Geoffrey W McCaughan, Mark D Gorrell

Cancers (Basel)· April 2021

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Deletion of fibroblast activation protein provides atheroprotection.
Sokrates Stein, Julien Weber, Stefanie Nusser-Stein, Jürgen Pahla, Hui E Zhang, Mark D Gorrell

Cardiovasc Res· March 2021

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DPP4 Inhibitor Sitagliptin Enhances Lymphocyte Recruitment and Prolongs Survival in a Syngeneic Ovarian Cancer Mouse Model.
Amy L Wilson, Laura R Moffitt, Kirsty L Wilson, Maree Bilandzic, Mark D Wright, Mark D Gorrell

Cancers (Basel)· January 2021

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A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2.
Cecy R Xi, Arianna Di Fazio, Naveed Ahmed Nadvi, Karishma Patel, Michelle Sui Wen Xiang, Mark D Gorrell

Molecules· November 2020

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Hypoxia Regulates DPP4 Expression, Proteolytic Inactivation, and Shedding from Ovarian Cancer Cells.
Laura R Moffitt, Maree Bilandzic, Amy L Wilson, Yiqian Chen, Mark D Gorrell

Int J Mol Sci· October 2020

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COVID-19 and comorbidities: A role for dipeptidyl peptidase 4 (DPP4) in disease severity?
Margaret F Bassendine, Simon H Bridge, Geoffrey W McCaughan, Mark D Gorrell

J Diabetes· September 2020

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Animal models for hepatocellular carcinoma.
Hui Emma Zhang, James M Henderson, Mark D Gorrell

Biochim Biophys Acta Mol Basis Dis· May 2019

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Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity.
Margaret G Gall, Hui Emma Zhang, Quintin Lee, Christopher J Jolly, Geoffrey W McCaughan, Mark D Gorrell

Sci Rep· May 2019

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Non-Invasive Fluorescent Monitoring of Ovarian Cancer in an Immunocompetent Mouse Model.
Amy L Wilson, Kirsty L Wilson, Maree Bilandzic, Laura R Moffitt, Ming Makanji, Mark D Gorrell

Cancers (Basel)· December 2018

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