Publications by authors named "Mark D Rackham"

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The medicinal chemistry of mitochondrial dysfunction: a critical overview of efforts to modulate mitochondrial health.
Maximillian Taro William Lee, William Mahy, Mark David Rackham

RSC Med Chem· August 2021

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A caged E3 ligase ligand for PROTAC-mediated protein degradation with light.
Cyrille S Kounde, Maria M Shchepinova, Charlie N Saunders, Marcel Muelbaier, Mark D Rackham

Chem Commun (Camb)· May 2020

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Discovery of high affinity inhibitors of -myristoyltransferase.
Mark D Rackham, Zhiyong Yu, James A Brannigan, William P Heal, Daniel Paape

Medchemcomm· October 2015

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Design and synthesis of high affinity inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferases directed by ligand efficiency dependent lipophilicity (LELP).
Mark D Rackham, James A Brannigan, Kaveri Rangachari, Stephan Meister, Anthony J Wilkinson

J Med Chem· March 2014

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Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach.
Megan H Wright, Barbara Clough, Mark D Rackham, Kaveri Rangachari, James A Brannigan

Nat Chem· February 2014

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N-Myristoyltransferase as a potential drug target in malaria and leishmaniasis.
Edward W Tate, Andrew S Bell, Mark D Rackham, Megan H Wright

Parasitology· January 2014

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Discovery of novel and ligand-efficient inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferase.
Mark D Rackham, James A Brannigan, David K Moss, Zhiyong Yu, Anthony J Wilkinson

J Med Chem· January 2013

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