Publications by authors named "Mark Daris"

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Multi-targeted, NOT gated CAR-T cells as a strategy to protect normal lineages for blood cancer therapy.
Breanna DiAndreth, Pavlo A Nesterenko, Aaron G Winters, Aaron D Flynn, Claudia A Jette, Mark Daris

Front Immunol· May 2025

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Onboard, tethered IL-12 boosts potency of the Tmod NOT gate and preserves selectivity.
Jingli A Zhang, Sara Imboden, Dongwoo Lee, Alexandre Zampieri, Sanam Shafaattalab, Mark E Daris

J Immunother Cancer· May 2025

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Geometric parameters that affect the behavior of logic-gated CAR T cells.
Alexander C Partin, Richele Bruno, Sanam Shafaattalab, Erica Vander Mause, Aaron Winters, Mark Daris

Front Immunol· February 2024

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Chimeric Antigen Receptors Directed at Mutant KRAS Exhibit an Inverse Relationship Between Functional Potency and Neoantigen Selectivity.
Talar Tokatlian, Grace E Asuelime, Martin S Naradikian, Jee-Young Mock, Mark E Daris

Cancer Res Commun· January 2022

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Mesothelin-specific CAR-T cell therapy that incorporates an HLA-gated safety mechanism selectively kills tumor cells.
Talar Tokatlian, Grace E Asuelime, Jee-Young Mock, Breanna DiAndreth, Shruti Sharma, Mark E Daris

J Immunother Cancer· January 2022

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Potent, Selective CARs as Potential T-Cell Therapeutics for HPV-positive Cancers.
Xueyin Wang, Mark L Sandberg, Aaron D Martin, Kathleen R Negri, Grant B Gabrelow, Mark E Daris

J Immunother· October 2021

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Design of TCR Structural Variants That Retain or Invert the Normal Activation Signal.
Jee-Young Mock, Julyun Oh, Jason Yi, Mark E Daris, Agnes Hamburger

Immunohorizons· May 2021

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Re-examination of MAGE-A3 as a T-cell Therapeutic Target.
Aaron D Martin, Xueyin Wang, Mark L Sandberg, Kathleen R Negri, Ming L Wu, Mark E Daris

J Immunother· April 2021

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Engineered IL-21 Cytokine Muteins Fused to Anti-PD-1 Antibodies Can Improve CD8+ T Cell Function and Anti-tumor Immunity.
Shanling Shen, Gail Sckisel, Anupama Sahoo, Almin Lalani, Doug Den Otter, Mark Daris

Front Immunol· March 2021

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HLA-A*02:01-directed chimeric antigen receptor/forkhead box P3-engineered CD4+ T cells adopt a regulatory phenotype and suppress established graft-versus-host disease.
Aaron Martin, Mark Daris, James A Johnston, Jiajia Cui

Cytotherapy· February 2021

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Engineered T cells directed at tumors with defined allelic loss.
Agnes E Hamburger, Breanna DiAndreth, Jiajia Cui, Mark E Daris, Melanie L Munguia

Mol Immunol· December 2020

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Structure-function relationships of chimeric antigen receptors in acute T cell responses to antigen.
Han Xu, Agnes E Hamburger, Jee-Young Mock, Xueyin Wang, Aaron D Martin, Mark E Daris

Mol Immunol· October 2020

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Creation of a High-Yield AAV Vector Production Platform in Suspension Cells Using a Design-of-Experiment Approach.
Huiren Zhao, Ki-Jeong Lee, Mark Daris, Yun Lin, Thomas Wolfe

Mol Ther Methods Clin Dev· September 2020

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Discovery, characterization, and remediation of a C-terminal Fc-extension in proteins expressed in CHO cells.
Christopher S Spahr, Mark E Daris, Kevin C Graham, Brian D Soriano, Jennitte L Stevens

MAbs· June 2019

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Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury.
Xiaodong Li, Mario Grisanti, Wei Fan, Frank J Asuncion, Hong-Lin Tan, Mark Daris, Kristi Daris

J Bone Miner Res· November 2011

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A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Joyce C Y Chan, Derek E Piper, Qiong Cao, Dongming Liu, Chadwick King, Mark Daris

Proc Natl Acad Sci U S A· June 2009

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Gene therapy with human recombinant osteoprotegerin reverses established osteopenia in ovariectomized mice.
Paul J Kostenuik, Brad Bolon, Sean Morony, Mark Daris, Zhaopo Geng

Bone· April 2004

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