Publications by authors named "Mark Duggan"

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Neighborhood Disadvantage and Risk of Hospitalization in a Home-Based Cardiac Rehabilitation Program After Acute Myocardial Infarction: A Retrospective Cohort Study.
Barune Thapa, Kristi Reynolds, Mark Duggan, Matthew T Mefford, Chileshe Nkonde-Price

J Am Heart Assoc· January 2026

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Partner History of Problematic Substance Use and Self-Reported Substance Use During Early Pregnancy: Findings from Kaiser Permanente Northern California, 2021-2022.
Rachel Gallegos, Natalie E Slama, Mark C Duggan, Deborah Ansley, Carley Castellanos

Matern Child Health J· November 2025

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Health-Related Social Needs and Total Healthcare Cost: A Cross-Sectional Study in a Large Integrated Health System.
Ariel R C Silverman, Paul J Chung, Michael K Gould, Quyen Ngo-Metzger, Maile M Tauali'i, Mark C Duggan

J Gen Intern Med· June 2025

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Comparing In-Person, Telephonic, and Video-Based Treatment of Depression in Adult Primary Care During the COVID-19 Pandemic.
Benjamin Metrikin, Rebecca L Hill, Jialuo Liu, John Adams, Mark C Duggan

Perm J· March 2025

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Colorectal Cancer Screening and Social Needs.
Isabelle R Franklin, Rebecca Gambatese, Mark C Duggan, Beverly B Green, Robert S Nocon

J Am Board Fam Med· February 2025

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Evaluation of Socioeconomic and Racial/Ethnic Disparities in All-Cause Mortality in Adolescents and Young Adults With Cancer.
Scott Henderson, Mark Duggan, Chun Chao, Robert Cooper

J Natl Compr Canc Netw· September 2024

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Why Does the Inflation Reduction Act Exclude Expensive Cancer Treatments in Price Negotiations?
Danea M Horn, Mireille Jacobson, Abby E Alpert, Mark G Duggan

JCO Oncol Pract· February 2024

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Technology enabled home-based cardiac rehabilitation among women with cardiovascular disease: A longitudinal cohort study.
Michael Najem, Mark Duggan, Rebecca Gambatese, Rebecca Hill, Su-Jau Yang

Int J Cardiol Cardiovasc Risk Prev· December 2023

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Emergency department visits respond nonlinearly to wildfire smoke.
Sam Heft-Neal, Carlos F Gould, Marissa L Childs, Mathew V Kiang, Kari C Nadeau, Mark Duggan

Proc Natl Acad Sci U S A· September 2023

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Biosimilar Competition and Payments in Medicare: The Case of Trastuzumab.
Danea M Horn, Abby E Alpert, Mark G Duggan, Nicolas A Garcia, Mireille Jacobson

JCO Oncol Pract· April 2023

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A Chemical Strategy toward Novel Brain-Penetrant EZH2 Inhibitors.
Rui Liang, Daisuke Tomita, Yusuke Sasaki, John Ginn, Mayako Michino, Mark Duggan

ACS Med Chem Lett· March 2022

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Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules.
Kamini Singh, Jianan Lin, Nicolas Lecomte, Prathibha Mohan, Askan Gokce, Mark Duggan

Cancer Res· April 2021

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Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations.
Jihong Li, Yoshiyuki Fukase, Yi Shang, Wei Zou, José M Muñoz-Félix, Mark Duggan

ACS Pharmacol Transl Sci· December 2019

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SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M PAMs.
Trevor C Chopko, Changho Han, Alison R Gregro, Darren W Engers, Andrew S Felts, Mark E Duggan

Bioorg Med Chem Lett· August 2019

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Corrigendum to "Challenges in the development of an M PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides" [Bioorg. Med. Chem. Lett. 27(23) (2017) 5179-5184].
James C Tarr, Michael R Wood, Meredith J Noetzel, Bruce J Melancon, Atin Lamsal, Mark E Duggan

Bioorg Med Chem Lett· September 2018

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Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity.
Patrik Johansson, Karin Kaspersson, Ian K Gurrell, Elisabeth Bäck, Susanna Eketjäll, Mark E Duggan

J Med Chem· April 2018

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Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M PAM VU0467154.
Robert W Gould, Michael D Grannan, Barak W Gunter, Jacob Ball, Michael Bubser, Mark E Duggan

Neuropharmacology· January 2018

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Challenges in the development of an M PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides.
James C Tarr, Michael R Wood, Meredith J Noetzel, Bruce J Melancon, Atin Lamsal, Mark E Duggan

Bioorg Med Chem Lett· December 2017

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The small molecule CLP257 does not modify activity of the K-Cl co-transporter KCC2 but does potentiate GABA receptor activity.
Ross A Cardarelli, Karen Jones, Lucie I Pisella, Heike J Wobst, Lisa J McWilliams, Mark E Duggan

Nat Med· December 2017

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Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes.
Jianjia Fan, Shahab Zareyan, Wenchen Zhao, Yoko Shimizu, Tom A Pfeifer, Mark E Duggan

PLoS One· August 2017

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Challenges in the development of an M PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides.
James C Tarr, Michael R Wood, Meredith J Noetzel, Jeanette L Bertron, Rebecca L Weiner, Mark E Duggan

Bioorg Med Chem Lett· July 2017

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Optimization of M positive allosteric modulators (PAMs): The discovery of VU0476406, a non-human primate in vivo tool compound for translational pharmacology.
Bruce J Melancon, Michael R Wood, Meredith J Noetzel, Kellie D Nance, Eileen M Engelberg, Mark E Duggan

Bioorg Med Chem Lett· June 2017

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Discovery of VU0467485/AZ13713945: An M PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia.
Michael R Wood, Meredith J Noetzel, Bruce J Melancon, Michael S Poslusney, Kellie D Nance, Mark E Duggan

ACS Med Chem Lett· February 2017

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Challenges in the development of an M PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs.
Michael R Wood, Meredith J Noetzel, Michael S Poslusney, Bruce J Melancon, James C Tarr, Mark E Duggan

Bioorg Med Chem Lett· January 2017

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Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition.
Michael R Wood, Meredith J Noetzel, James C Tarr, Alice L Rodriguez, Atin Lamsal, Mark E Duggan

Bioorg Med Chem Lett· September 2016

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